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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis

Authors:
Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S
Citation:
Dev Biol. 2017 Dec 8. pii: S0012-1606(17)30430-X. doi: 10.1016/j.ydbio.2017.11.017. [Epub ahead of print]
Epub:
Yes
Abstract:
The transcription factors GATA4, GATA5 and GATA6 are important regulators of heart muscle differentiation (cardiomyogenesis),...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S. Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis. Dev Biol. 2017 Dec 8. pii: S0012-1606(17)30430-X. doi: 10.1016/j.ydbio.2017.11.017. [Epub ahead of print].

Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis

Authors:
Singh BN, Tahara N, Kawakami Y, Das S, Koyano-Nakagawa N, Gong W, Garry MG, Garry DJ
Citation:
PLoS One. 2017 Dec 12;12(12):e0189010. doi: 10.1371/journal.pone.0189010. eCollection 2017
Epub:
Not Epub
Abstract:
Remodeling of the primitive vasculature is necessary for the formation of a complex branched vascular architecture. However,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Singh BN, Tahara N, Kawakami Y, Das S, Koyano-Nakagawa N, Gong W, Garry MG, Garry DJ. Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis. PLoS One. 2017 Dec 12;12(12):e0189010. doi: 10.1371/journal.pone.0189010. eCollection 2017.

Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy

Authors:
Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri M, Takashima S, Kitakaze M, Hayashi K
Citation:
Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y
Epub:
Not Epub
Abstract:
The pathogenesis of heart failure associated with dilated cardiomyopathy (DCM) may result in part from adenosine triphosphate (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri M, Takashima S, Kitakaze M, Hayashi K. Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy. Sci Rep. 2017;7:17417. doi:10.1038/s41598-017-17572-y.

In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw

Authors:
McGurk PD, Swartz ME, Chen JW, Galloway JL, Eberhart JK
Citation:
PLoS Genet. 2017;13(12):e1007112. doi:10.1371/journal.pgen.1007112
Epub:
Not Epub
Abstract:
Integrated development of diverse tissues gives rise to a functional, mobile vertebrate musculoskeletal system. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGurk PD, Swartz ME, Chen JW, Galloway JL, Eberhart JK. In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw. PLoS Genet. 2017;13(12):e1007112. doi:10.1371/journal.pgen.1007112.

A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure

Authors:
Hung CY, Volkmar B, Baker JD, Bauer JW, Gussoni E, Hainzl S, Klausegger A, Lorenzo J, Mihalek I, Rittinger O, Tekin M, Dallman JE, Bodamer OA
Citation:
PLoS ONE. 2017;12(12):e0189324. doi:10.1371/journal.pone.0189324
Epub:
Not Epub
Abstract:
Primordial growth failure has been linked to defects in the biology of cell division and replication. The complex processes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung CY, Volkmar B, Baker JD, Bauer JW, Gussoni E, Hainzl S, Klausegger A, Lorenzo J, Mihalek I, Rittinger O, Tekin M, Dallman JE, Bodamer OA. A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure. PLoS ONE. 2017;12(12):e0189324. doi:10.1371/journal.pone.0189324.

EphA7 regulates claudin6 and pronephros development in Xenopus

Authors:
Sun J, Wang X, Shi Y, Li J, Li C, Shi Z, Chen Y, Mao B
Citation:
Biochem Biophys Res Commun. 2017 Dec 6. pii: S0006-291X(17)32412-9. doi: 10.1016/j.bbrc.2017.12.027. [Epub ahead of print]
Epub:
Yes
Abstract:
Eph/ephrin molecules are widely expressed during embryonic development, and function in a variety of developmental processes....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sun J, Wang X, Shi Y, Li J, Li C, Shi Z, Chen Y, Mao B. EphA7 regulates claudin6 and pronephros development in Xenopus. Biochem Biophys Res Commun. 2017 Dec 6. pii: S0006-291X(17)32412-9. doi: 10.1016/j.bbrc.2017.12.027. [Epub ahead of print].

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase

Authors:
Patrikainen MS, Tolvanen MEE, Aspatwar A, Barker HR, Ortutay C, Jänis J, Laitaoja M, Hytönen VP, Azizi L, Manandhar P, Jáger E, Vullo D, Kukkurainen S, Hilvo M, Supuran CT, Parkkila S
Citation:
PeerJ. 2017;5:e4128 doi:10.7717/peerj.4128
Epub:
Not Epub
Abstract:
Background: Carbonic anhydrases (CAs) are ubiquitous, essential enzymes which catalyze the conversion of carbon dioxide and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patrikainen MS, Tolvanen MEE, Aspatwar A, Barker HR, Ortutay C, Jänis J, Laitaoja M, Hytönen VP, Azizi L, Manandhar P, Jáger E, Vullo D, Kukkurainen S, Hilvo M, Supuran CT, Parkkila S. Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase. PeerJ. 2017;5:e4128 doi:10.7717/peerj.4128.

Nodal patterning without Lefty inhibitory feedback is functional but fragile

Authors:
Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF
Citation:
Elife. 2017 Dec 7;6. pii: e28785. doi: 10.7554/eLife.28785
Epub:
Not Epub
Abstract:
Developmental signaling pathways often activate their own inhibitors. Such inhibitory feedback has been suggested to restrict...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF. Nodal patterning without Lefty inhibitory feedback is functional but fragile. Elife. 2017 Dec 7;6. pii: e28785. doi: 10.7554/eLife.28785.

Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus

Authors:
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M
Citation:
Nat Commun. 2017 Dec 7;8(1):1973. doi: 10.1038/s41467-017-02076-0
Epub:
Not Epub
Abstract:
Wnt proteins direct embryonic patterning, but the regulatory basis of their distribution and signal reception remain unclear....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M. Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus. Nat Commun. 2017 Dec 7;8(1):1973. doi: 10.1038/s41467-017-02076-0.

Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo

Authors:
Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB
Citation:
Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003
Epub:
Not Epub
Abstract:
Interactions between tumor cells and tumor-associated macrophages play critical roles in the initiation of tumor cell motility...
Citation Extract:
Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB. Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo. Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003.

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