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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafish
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Citation:
Mol Metab. 2017 Nov 22. pii: S2212-8778(17)30877-3. doi: 10.1016/j.molmet.2017.11.006. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: Adult human kidneys produce erythropoietin (EPO), which regulates red blood cell formation; however, whether EPO... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: She J, Yuan Z, Wu Y, Chen J, Kroll J. Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafish. Mol Metab. 2017 Nov 22. pii: S2212-8778(17)30877-3. doi: 10.1016/j.molmet.2017.11.006. [Epub ahead of print]. |
Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep
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Citation:
Amino Acids. 2017 Dec 2. doi: 10.1007/s00726-017-2515-1. [Epub ahead of print] Epub:
Yes Abstract:
This study investigated the effect of agmatine (Agm) in proliferation of ovine trophecdoderm cells (oTr1) as well as the... Organism or Cell Type:
Ovis aries (sheep) Citation Extract: Lenis YY, Elmetwally MA, Tang W, Satterfield C, Dunlap K, Wu G, Bazer FW. Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep. Amino Acids. 2017 Dec 2. doi: 10.1007/s00726-017-2515-1. [Epub ahead of print]. |
Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis
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Citation:
Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9 Epub:
Not Epub Abstract:
Thyroid hormones (THs) are essential for embryonic brain development but the genetic mechanisms involved in the action of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Silva N, Louro B, Trindade M, Power DM, Campinho MA. Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis. Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9. |
Inhibition of Delta-induced Notch signaling using fucose analogs
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Citation:
Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print] Epub:
Yes Abstract:
Notch is a cell-surface receptor that controls cell-fate decisions and is regulated by O-glycans attached to epidermal growth... Organism or Cell Type:
zebrafish Citation Extract: Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS. Inhibition of Delta-induced Notch signaling using fucose analogs. Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print]. |
Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm
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Citation:
Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3 Epub:
Not Epub Abstract:
Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vierstraete J, Willaert A, Vermassen P, Coucke PJ, Vral A, Claes KBM. Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm. Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3. |
Role of WNT10A in failure of tooth development in humans and zebrafish
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Citation:
Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14 Epub:
Not Epub Abstract:
BACKGROUND: Oligodontia is a severe form of tooth agenesis characterized by the absence of six or more permanent teeth.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A. Role of WNT10A in failure of tooth development in humans and zebrafish. Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14. |
Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development
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Citation:
J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print] Epub:
Yes Abstract:
TBX5 plays a critical role in heart and forelimb development. Mutations in TBX5 cause Holt-Oram syndrome, an autosomal dominant... Organism or Cell Type:
zebrafish Citation Extract: Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD. Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development. J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print]. |
Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function
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Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565 Epub:
Yes Abstract:
Multiciliated cells (MCCs) drive fluid flow in diverse tubular organs and are essential for the development and homeostasis of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Fan Tu, Jakub Sedzinski, Yun Ma, Edward M. Marcotte, John B. Wallingford. Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565. |
Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes
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Citation:
Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y Epub:
Not Epub Abstract:
Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D’Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, Martí E, D’Aniello S, Spagnuolo A, Ristoratore F, Arnone MI, Garcia-Fernàndez J, Irimia M. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y. |
The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells
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Citation:
Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28 Epub:
Not Epub Abstract:
The oncogene ETS-related gene (ERG) encodes a transcription factor with roles in the regulation of haematopoiesis, angiogenesis... Delivery Method:
Vivo-Morpholino + Endo-Porter Organism or Cell Type:
cell culture: VCaP (ATCC CRL-2876) Citation Extract: Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR. The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells. Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28. |