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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Functional analysis of the cfdp1 gene in zebrafish provides evidence for its crucial role in craniofacial development and osteogenesis

Authors:
Celauro E, Carra S, Rodriguez A, Cotelli F, Dimitri P
Citation:
Exp Cell Res. 2017 Oct 26. pii: S0014-4827(17)30570-0. doi: 10.1016/j.yexcr.2017.10.022. [Epub ahead of print]
Epub:
Yes
Abstract:
The CFDP1 proteins have been linked to craniofacial development and osteogenesis in vertebrates, though specific human...
Link:
http://www.sciencedirect.com/science/article/pii/S0014482717305700
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Celauro E, Carra S, Rodriguez A, Cotelli F, Dimitri P. Functional analysis of the cfdp1 gene in zebrafish provides evidence for its crucial role in craniofacial development and osteogenesis. Exp Cell Res. 2017 Oct 26. pii: S0014-4827(17)30570-0. doi: 10.1016/j.yexcr.2017.10.022. [Epub ahead of print].

Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

Authors:
Brennan JJ, Messerschmidt JL, Williams LM, Matthews BJ, Reynoso M, Gilmore TD
Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1711530114
Epub:
Yes
Abstract:
In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream...
Link:
http://www.pnas.org/content/early/2017/11/03/1711530114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Brennan JJ, Messerschmidt JL, Williams LM, Matthews BJ, Reynoso M, Gilmore TD. Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1711530114 .

Spindle asymmetry drives non-Mendelian chromosome segregation

Authors:
Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA
Citation:
Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092
Epub:
Not Epub
Abstract:
Genetic elements compete for transmission through meiosis, when haploid gametes are created from a diploid parent. Selfish...
Link:
http://science.sciencemag.org/content/358/6363/668
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA. Spindle asymmetry drives non-Mendelian chromosome segregation. Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092.

Frizzled-7 is required for Xenopus heart development

Authors:
Abu-Elmagd M, Mulvaney J, Wheeler GN
Citation:
Biol Open. 2017 Nov 3. pii: bio.026963. doi: 10.1242/bio.026963. [Epub ahead of print]
Epub:
Yes
Abstract:
Wnt signalling regulates cardiogenesis during specification of heart tissue and the morphogenetic movements necessary to form...
Link:
http://bio.biologists.org/content/early/2017/11/02/bio.026963.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abu-Elmagd M, Mulvaney J, Wheeler GN. Frizzled-7 is required for Xenopus heart development. Biol Open. 2017 Nov 3. pii: bio.026963. doi: 10.1242/bio.026963. [Epub ahead of print].

Profilin 1 plays feedback role in actin-mediated polar body extrusion in mouse oocytes

Authors:
Liu J, Wang QC, Duan X, Cui XS, Kim NH, Zhang Y, Sun SC
Citation:
Reprod Fertil Dev. 2017 Nov 3. doi: 10.1071/RD17354. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocytes undergo several crucial processes during meiosis maturation, including spindle formation and migration and...
Link:
http://www.publish.csiro.au/RD/RD17354
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Liu J, Wang QC, Duan X, Cui XS, Kim NH, Zhang Y, Sun SC. Profilin 1 plays feedback role in actin-mediated polar body extrusion in mouse oocytes. Reprod Fertil Dev. 2017 Nov 3. doi: 10.1071/RD17354. [Epub ahead of print].

Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease

Authors:
Hu Z-y, Chen B, Zhang J-p, Ma Y-y
Citation:
J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795
Epub:
Not Epub
Abstract:
Parkinson's disease (PD) is one of the most epidemic neurodegenerative diseases and is characterized by movement disorders...
Link:
http://www.jbc.org/content/292/44/18062.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu Z-y, Chen B, Zhang J-p, Ma Y-y. Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease. J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795.

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

Authors:
Sanna-Cherchi S, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M, Otto EA, Sampson G, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Liu Q, Na Y-J, Goj V, Ardissino G, Gigante M, Gesualdo L, Janezcko M, Zaniew M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JAE, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Kiryluk A-M, Mane S, Goldstein DB, Lifton RP, Katsanis N, Davis EE, Gharavi AG
Citation:
Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018
Epub:
Not Epub
Abstract:
Renal agenesis and hypodysplasia (RHD) are major causes of pediatric chronic kidney disease and are highly genetically...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(17)30387-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sanna-Cherchi S, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M, Otto EA, Sampson G, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Liu Q, Na Y-J, Goj V, Ardissino G, Gigante M, Gesualdo L, Janezcko M, Zaniew M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JAE, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Kiryluk A-M, Mane S, Goldstein DB, Lifton RP, Katsanis N, Davis EE, Gharavi AG. Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations. Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018.

Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development

Authors:
St Clair RM, Emerson SE, D'Elia KP, Weir ME, Schmoker AM, Ebert AM, Ballif BA
Citation:
FEBS J. 2017 Nov 1. doi: 10.1111/febs.14313. [Epub ahead of print]
Epub:
Yes
Abstract:
Plexins (Plxns) are semaphorin (Sema) receptors that play important signaling roles, particularly in the developing nervous...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/febs.14313/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
St Clair RM, Emerson SE, D'Elia KP, Weir ME, Schmoker AM, Ebert AM, Ballif BA. Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development. FEBS J. 2017 Nov 1. doi: 10.1111/febs.14313. [Epub ahead of print].

Znf703, a novel target of Pax3 and Zic1, regulates hindbrain and neural crest development in Xenopus

Authors:
Hong CS, Saint-Jeannet JP
Citation:
Genesis. 2017 Oct 31. doi: 10.1002/dvg.23082. [Epub ahead of print]
Epub:
Yes
Abstract:
The transcription factors Pax3 and Zic1 are critical to specify the neural plate border and to promote neural crest formation....
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvg.23082/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hong CS, Saint-Jeannet JP. Znf703, a novel target of Pax3 and Zic1, regulates hindbrain and neural crest development in Xenopus. Genesis. 2017 Oct 31. doi: 10.1002/dvg.23082. [Epub ahead of print].

Cohesin mediates Esco2-dependent transcriptional regulation in zebrafish regenerating fin model of Roberts syndrome

Authors:
Banerji R, Skibbens RV, Iovine MK
Citation:
Biol Open. 2017 Oct 30. pii: bio.026013. doi: 10.1242/bio.026013. [Epub ahead of print]
Epub:
Yes
Abstract:
Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial...
Link:
http://bio.biologists.org/content/early/2017/10/27/bio.026013.long
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Banerji R, Skibbens RV, Iovine MK. Cohesin mediates Esco2-dependent transcriptional regulation in zebrafish regenerating fin model of Roberts syndrome. Biol Open. 2017 Oct 30. pii: bio.026013. doi: 10.1242/bio.026013. [Epub ahead of print].

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