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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages

Authors:
van Boxtel AL, Economou AD, Heliot C, Hill CS
Citation:
Dev Cell. 2017 Dec 20. pii: S1534-5807(17)30982-6. doi: 10.1016/j.devcel.2017.11.021. [Epub ahead of print]
Epub:
Yes
Abstract:
Specification of the three germ layers by graded Nodal signaling has long been seen as a paradigm for patterning through a...
Link:
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30982-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Boxtel AL, Economou AD, Heliot C, Hill CS. Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages. Dev Cell. 2017 Dec 20. pii: S1534-5807(17)30982-6. doi: 10.1016/j.devcel.2017.11.021. [Epub ahead of print].

Role of the Visual Experience-Dependent Nascent Proteome in Neuronal Plasticity

Authors:
Liu H-H, McClatchy DB, Schiapparelli L, Shen W, Yates JR III, Cline HT
Citation:
bioRxiv. 2017. doi:10.1101/240119
Epub:
Yes
Abstract:
Experience-dependent synaptic plasticity refines brain circuits during development. To identify novel protein synthesis-...
Link:
https://www.biorxiv.org/content/early/2017/12/27/240119
Delivery Method:
intracerebroventricular injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu H-H, McClatchy DB, Schiapparelli L, Shen W, Yates JR III, Cline HT. Role of the Visual Experience-Dependent Nascent Proteome in Neuronal Plasticity. bioRxiv. 2017. doi:10.1101/240119.

Long-Term Pulmonary Function in Duchenne Muscular Dystrophy: Comparison of Eteplirsen-Treated Patients to Natural History

Authors:
Kinane TB, Mayer OH, Duda PW, Lowes LP, Moody SL, Mendell JR
Citation:
J Neuromusc Dis. 2017;[Epub ahead of print] doi:10.3233/JND-170272
Epub:
Not Epub
Abstract:
Background: Duchenne muscular dystrophy (DMD) is a rare, degenerative, X-linked genetic disease that results in progressive...
Link:
https://content.iospress.com/articles/journal-of-neuromuscular-diseases/jnd170272
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Kinane TB, Mayer OH, Duda PW, Lowes LP, Moody SL, Mendell JR. Long-Term Pulmonary Function in Duchenne Muscular Dystrophy: Comparison of Eteplirsen-Treated Patients to Natural History. J Neuromusc Dis. 2017;[Epub ahead of print] doi:10.3233/JND-170272.

Rnf152 Is Essential for NeuroD Expression and Delta-Notch Signaling in the Zebrafish Embryos

Authors:
Kumar A, Huh TL, Choe J, Rhee M
Citation:
Mol Cells. 2017 Dec 22. doi: 10.14348/molcells.2017.0216. [Epub ahead of print]
Epub:
Yes
Abstract:
We report the biological functions of a zebrafish homologue of RING-finger protein 152 (rnf152) during embryogenesis. rnf152...
Link:
http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2017.0216&
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumar A, Huh TL, Choe J, Rhee M. Rnf152 Is Essential for NeuroD Expression and Delta-Notch Signaling in the Zebrafish Embryos. Mol Cells. 2017 Dec 22. doi: 10.14348/molcells.2017.0216. [Epub ahead of print].

Whole-exome sequencing reveals POC5 as a novel gene associated with autosomal recessive retinitis pigmentosa

Authors:
Weisz Hubshman M, Broekman S, van Wijk E, Cremers F, Abu-Diab A, Samer K, Tzur S, Lagovsky I, Smirin-Yosef P, Sharon D, Haer-Wigman L, Banin E, Basel-Vanagaite L, de Vrieze E
Citation:
Hum Mol Genet. 2017 Dec 19. doi: 10.1093/hmg/ddx428. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinitis pigmentosa (RP), the most common form of inherited retinal degeneration, is associated with different groups of genes...
Link:
https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddx428/4760480
Organism or Cell Type:
zebrafish
Citation Extract:
Weisz Hubshman M, Broekman S, van Wijk E, Cremers F, Abu-Diab A, Samer K, Tzur S, Lagovsky I, Smirin-Yosef P, Sharon D, Haer-Wigman L, Banin E, Basel-Vanagaite L, de Vrieze E. Whole-exome sequencing reveals POC5 as a novel gene associated with autosomal recessive retinitis pigmentosa. Hum Mol Genet. 2017 Dec 19. doi: 10.1093/hmg/ddx428. [Epub ahead of print].

G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish

Authors:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P
Citation:
Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print]
Epub:
Yes
Abstract:
Haemostasis is a defence mechanism that has evolved to protect organisms from losing their circulating fluid. We have...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/bjh.15046/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P. G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish. Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print].

RNA helicase Mov10 is essential for gastrulation and CNS development

Authors:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S
Citation:
Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Mov10 is an RNA helicase that modulates access of Argonaute 2 to microRNA recognition elements in mRNAs. We...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24615/full
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S. RNA helicase Mov10 is essential for gastrulation and CNS development. Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print].

Epigenetic Regulators Modulate Muscle Damage in Duchenne Muscular Dystrophy Model

Authors:
Bajanca F, Vandel L
Citation:
PLOS Currents Muscular Dystrophy. 2017. Edition 1. doi:10.1371/currents.md.f1e2379fa632f8135577333dd92ca83b
Epub:
Not Epub
Abstract:
Histone acetyl transferases (HATs) and histone deacetylases (HDAC) control transcription during myogenesis. HDACs promote...
Link:
http://currents.plos.org/md/article/epigenetic-regulators-modulate-muscle-damage-in-duchenne-muscular-dystrophy-model/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bajanca F, Vandel L. Epigenetic Regulators Modulate Muscle Damage in Duchenne Muscular Dystrophy Model. PLOS Currents Muscular Dystrophy. 2017. Edition 1. doi:10.1371/currents.md.f1e2379fa632f8135577333dd92ca83b.

Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos

Authors:
Dasgupta S, Vliet SM, Kupsco A, Leet JK, Altomare D, Volz DC
Citation:
PeerJ. 2017 Dec 14;5:e4156. doi: 10.7717/peerj.4156. eCollection 2017
Epub:
Not Epub
Abstract:
Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume organophosphate flame retardant widely used within...
Link:
https://peerj.com/articles/4156/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dasgupta S, Vliet SM, Kupsco A, Leet JK, Altomare D, Volz DC. Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos. PeerJ. 2017 Dec 14;5:e4156. doi: 10.7717/peerj.4156. eCollection 2017.

Vivo-morpholino oligomers strongly inhibit dengue virus replication and production

Authors:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT
Citation:
Arch Virol. 2018 Apr;163(4):867-876. doi: 10.1007/s00705-017-3666-9. Epub 2017 Dec 19. PMID: 29260328
Epub:
Yes
Abstract:
Dengue virus (DENV) infection is a worldwide public health problem, which can cause severe dengue hemorrhagic fever (DHF) and...
Link:
https://link.springer.com/article/10.1007/s00705-017-3666-9
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Vero, A549, U937, primary human monocytes
Citation Extract:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT. Vivo-morpholino oligomers strongly inhibit dengue virus replication and production. Arch Virol. 2018 Apr;163(4):867-876. doi: 10.1007/s00705-017-3666-9. Epub 2017 Dec 19. PMID: 29260328.

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