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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression
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Citation:
Biochim Biophys Acta. 2018 Jan 26. pii: S1874-9399(17)30309-7. doi: 10.1016/j.bbagrm.2017.12.009. [Epub ahead of print] Epub:
Yes Abstract:
The histone demethylase Jmjd3 plays a critical role in in cell lineage specification and differentiation at various stages of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, Deng M, Zon LI, Zhou Y, Zhu J, Xu PF, Liu TX. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochim Biophys Acta. 2018 Jan 26. pii: S1874-9399(17)30309-7. doi: 10.1016/j.bbagrm.2017.12.009. [Epub ahead of print]. |
The pivotal role of aristaless in development and evolution of diverse antennal morphologies in moths and butterflies
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Citation:
BMC Evol Biol. 2018 Jan 25;18(1):8. doi: 10.1186/s12862-018-1124-2 Epub:
Not Epub Abstract:
BACKGROUND: Antennae are multi-segmented appendages and main odor-sensing organs in insects. In Lepidoptera (moths and... Delivery Method:
electroporation Organism or Cell Type:
Bombyx mori (silk moth) Citation Extract: Ando T, Fujiwara H, Kojima T. The pivotal role of aristaless in development and evolution of diverse antennal morphologies in moths and butterflies. BMC Evol Biol. 2018 Jan 25;18(1):8. doi: 10.1186/s12862-018-1124-2. |
A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target
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Citation:
Brain 2018;awx364. doi:10.1093/brain/awx364 Epub:
Not Epub Abstract:
Despite the development of newer anti-seizure medications over the past 50 years, 30-40% of patients with epilepsy remain... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma S-C, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim D-Y, Rho JM, Kurrasch DM. A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target. Brain 2018;awx364. doi:10.1093/brain/awx364. |
Nodal induces sequential restriction of germ cell factors during primordial germ cell specification
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Citation:
Development. 2018;145(2):dev155663. doi:10.1242/dev.155663 Epub:
Not Epub Abstract:
Specification of the germ cell lineage is required for sexual reproduction in animals. The mechanism of germ cell specification... Delivery Method:
microinjection Organism or Cell Type:
sea star Citation Extract: Fresques TM, Wessel GM. Nodal induces sequential restriction of germ cell factors during primordial germ cell specification. Development. 2018;145(2):dev155663. doi:10.1242/dev.155663. |
Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings
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Citation:
PLoS Genet. 2018 Jan 22;14(1):e1007138. doi: 10.1371/journal.pgen.1007138. [Epub ahead of print] Epub:
Not Epub Abstract:
Congenital or neonatal cardiomyopathies are commonly associated with a poor prognosis and have multiple etiologies. In two... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Louw JJ, Nunes Bastos R, Chen X, Verdood C, Corveleyn A, Jia Y, Breckpot J, Gewillig M, Peeters H, Santoro MM, Barr F, Devriendt K. Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings. PLoS Genet. 2018 Jan 22;14(1):e1007138. doi: 10.1371/journal.pgen.1007138. [Epub ahead of print]. |
Monitoring dissociation kinetics during electrophoretic focusing enables high-specificity nucleic acid detection
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Citation:
Angew Chem. 2018;[Epub ahead of print] doi:10.1002/ange.201711673 Epub:
Yes Abstract:
A wide range of medical conditions can be diagnosed through sequence-specific analysis of nucleic acids. However, a major... Citation Extract: Zeidman Kalman T, Khalandovsky R, Tenenbaum Gonikman E, Bercovici M. Monitoring dissociation kinetics during electrophoretic focusing enables high-specificity nucleic acid detection. Angew Chem. 2018;[Epub ahead of print] doi:10.1002/ange.201711673. |
Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish
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Citation:
Blood. 2018 Jan 16. pii: blood-2017-07-797795. doi: 10.1182/blood-2017-07-797795. [Epub ahead of print] Epub:
Yes Abstract:
During development, hematopoietic stem cells (HSCs) derive from specialized endothelial cells (ECs), called hemogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gerri C, Marass M, Rossi A, Stainier DYR. Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood. 2018 Jan 16. pii: blood-2017-07-797795. doi: 10.1182/blood-2017-07-797795. [Epub ahead of print]. |
Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish
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Citation:
Am J. Pathol. 2018;[Epub ahead of print] doi:10.1016/j.ajpath.2017.12.005 Epub:
Yes Abstract:
CHARGE syndrome is a congenital disorder affecting multiple organs and mainly caused by mutations in CHD7, a gene encoding a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Z-Z, Wang Z-L, Choi T-I, Huang W-T, Wang H-T, Han Y-Y, Zhu L-Y, Kim H-T, Choi J-H, Lee J-S, Kim H-G, Zhao J, Chen Y, Lu Z, Tian X-L, Pan B-X, Li B-M, Kim C-H. Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. Am J. Pathol. 2018;[Epub ahead of print] doi:10.1016/j.ajpath.2017.12.005. |
Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia
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Citation:
Sci Signal. 2018;11(513):eaan6831. doi:10.1126/scisignal.aan6831 Epub:
Not Epub Abstract:
The transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) family of cytokines critically regulates vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang X, Wooderchak-Donahue WL, McDonald J, Ghatpande P, Baalbaki M, Sandoval M, Hart D, Clay H, Coughlin S, Lagna G, Bayrak-Toydemir P, Hata A. Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia. Sci Signal. 2018;11(513):eaan6831. doi:10.1126/scisignal.aan6831. |
Microinjection of Antisense Morpholinos, CRISPR/Cas9 RNP, and RNA/DNA into Zebrafish Embryos
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Citation:
Methods Mol Biol. 2018;1742:205-211. doi: 10.1007/978-1-4939-7665-2_18 Epub:
Not Epub Abstract:
In this chapter, we describe a stepwise protocol of microinjection. Using this method, antisense morpholinos, CRISPR-Cas9... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xin Y, Duan C. Microinjection of Antisense Morpholinos, CRISPR/Cas9 RNP, and RNA/DNA into Zebrafish Embryos. Methods Mol Biol. 2018;1742:205-211. doi: 10.1007/978-1-4939-7665-2_18. |