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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response

Authors:
Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S
Citation:
Biochem Biophys Res Commun. 2018 Jan 10. pii: S0006-291X(18)30066-4. doi: 10.1016/j.bbrc.2018.01.060. [Epub ahead of print]
Epub:
Yes
Abstract:
Sarcomeric protein turnover needs to be tightly balanced to assure proper assembly and renewal of sarcomeric units within...
Citation Extract:
Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S. Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response. Biochem Biophys Res Commun. 2018 Jan 10. pii: S0006-291X(18)30066-4. doi: 10.1016/j.bbrc.2018.01.060. [Epub ahead of print].

Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish

Authors:
Menezes FP, Machado Torresini F, Nery LR, da Silva RS
Citation:
Mol Neurobiol. 2018 Jan 11. doi: 10.1007/s12035-017-0850-6. [Epub ahead of print]
Epub:
Yes
Abstract:
Adenosinergic signaling has important effects on brain function, anatomy, and physiology in both late and early stages of...
Organism or Cell Type:
zebrafish
Citation Extract:
Menezes FP, Machado Torresini F, Nery LR, da Silva RS. Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish. Mol Neurobiol. 2018 Jan 11. doi: 10.1007/s12035-017-0850-6. [Epub ahead of print].

Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics

Authors:
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ
Citation:
Methods Mol Biol. 2018;1736:147-156. doi: 10.1007/978-1-4939-7638-6_14
Epub:
Not Epub
Abstract:
Investigating bacterial dynamics within the infected host has proved very useful for understanding mechanisms of pathogenesis....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics. Methods Mol Biol. 2018;1736:147-156. doi: 10.1007/978-1-4939-7638-6_14.

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Authors:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y
Citation:
Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y. Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis. Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8.

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Authors:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y
Citation:
Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y. Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis. Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8.

The function of tcf3 in medaka embryos: efficient knockdown with pePNAs

Authors:
Doenz G, Dorn S, Aghaallaei N, Bajoghli B, Riegel E, Aigner M, Bock H, Werner B, Lindhorst T, Czerny T
Citation:
BMC Biotechnol. 2018 Jan 9;18(1):1. doi: 10.1186/s12896-017-0411-0
Epub:
Not Epub
Abstract:
BACKGROUND: The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Doenz G, Dorn S, Aghaallaei N, Bajoghli B, Riegel E, Aigner M, Bock H, Werner B, Lindhorst T, Czerny T. The function of tcf3 in medaka embryos: efficient knockdown with pePNAs. BMC Biotechnol. 2018 Jan 9;18(1):1. doi: 10.1186/s12896-017-0411-0.

Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina

Authors:
Icha J, Kunath C, Rocha-Martins M, Norden C
Citation:
J Cell Biol. 2016 Oct 24;215(2):259-275
Epub:
Not Epub
Abstract:
The arrangement of neurons into distinct layers is critical for neuronal connectivity and function. During development, most...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Icha J, Kunath C, Rocha-Martins M, Norden C. Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina. J Cell Biol. 2016 Oct 24;215(2):259-275.

Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms

Authors:
Khor JM, Ettensohn CA
Citation:
Elife. 2017 Nov 20;6. pii: e32728. doi: 10.7554/eLife.32728
Epub:
Not Epub
Abstract:
Alx1 is a pivotal transcription factor in a gene regulatory network that controls skeletogenesis throughout the echinoderm...
Delivery Method:
microinjection
Organism or Cell Type:
Lytechnius variegatus (sea urchin)
Citation Extract:
Khor JM, Ettensohn CA. Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms. Elife. 2017 Nov 20;6. pii: e32728. doi: 10.7554/eLife.32728.

In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly

Authors:
Berger J, Berger S, Li M, Jacoby AS, Arner A, Bavi N, Stewart AG, Currie PD
Citation:
Cell Rep. 2018;22(2):313-22. doi:10.1016/j.celrep.2017.12.069
Epub:
Not Epub
Abstract:
The TCP-1 ring complex (TRiC) is a multi-subunit group II chaperonin that assists nascent or misfolded proteins to attain their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berger J, Berger S, Li M, Jacoby AS, Arner A, Bavi N, Stewart AG, Currie PD. In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly. Cell Rep. 2018;22(2):313-22. doi:10.1016/j.celrep.2017.12.069.

Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia

Authors:
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR
Citation:
J Cell Biol. 2018 Jan 4. pii: jcb.201709118. doi: 10.1083/jcb.201709118. [Epub ahead of print]
Epub:
Yes
Abstract:
Mechanisms that sense and regulate epithelial morphogenesis, integrity, and homeostasis are incompletely understood. Protease-...
Organism or Cell Type:
zebrafish
Citation Extract:
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR. Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia. J Cell Biol. 2018 Jan 4. pii: jcb.201709118. doi: 10.1083/jcb.201709118. [Epub ahead of print].

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