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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene

Authors:
Greer KL, Lochmüller H, Flanigan K, Fletcher S, Wilton SD
Citation:
Molec Ther Nucleic Acids. 2014;3,e155. doi:10.1038/mtna.2014.8
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy is a severe muscle-wasting disease caused by mutations in the dystrophin gene that ablate...
Link:
http://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(16)30295-5
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: primary fibroblasts induced myogenic
Citation Extract:
Greer KL, Lochmüller H, Flanigan K, Fletcher S, Wilton SD. Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene. Molec Ther Nucleic Acids. 2014;3,e155. doi:10.1038/mtna.2014.8.

Distinct Notch signaling outputs pattern the developing arterial system

Authors:
Quillien A, Moore JC, Shin M, Siekmann AF, Smith T, Pan L, Moens CB, Parsons MJ, Lawson ND
Citation:
Development. 2014 Mar 5. [Epub ahead of print]
Epub:
Yes
Abstract:
Differentiation of arteries and veins is essential for the development of a functional circulatory system. In vertebrate...
Link:
http://dev.biologists.org/content/141/7/1544.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quillien A, Moore JC, Shin M, Siekmann AF, Smith T, Pan L, Moens CB, Parsons MJ, Lawson ND. Distinct Notch signaling outputs pattern the developing arterial system. Development. 2014 Mar 5. [Epub ahead of print].

Sub-circuits of a gene regulatory network control a developmental epithelial-mesenchymal transition

Authors:
Saunders LR, McClay DR
Citation:
Development. 2014 Mar 5. [Epub ahead of print]
Epub:
Yes
Abstract:
Epithelial-mesenchymal transition (EMT) is a fundamental cell state change that transforms epithelial to mesenchymal cells...
Link:
http://dev.biologists.org/content/141/7/1503.abstract
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin Lytechinus variegatus
Citation Extract:
Saunders LR, McClay DR. Sub-circuits of a gene regulatory network control a developmental epithelial-mesenchymal transition. Development. 2014 Mar 5. [Epub ahead of print].

Pitx2c ensures habenular asymmetry by restricting parapineal cell number

Authors:
Garric L, Ronsin B, Roussigné M, Booton S, Gamse JT, Dufourcq P, Blader P
Citation:
Development. 2014 Mar 5. [Epub ahead of print]
Epub:
Yes
Abstract:
Left-right (L/R) asymmetries in the brain are thought to underlie lateralised cognitive functions. Understanding how...
Link:
http://dev.biologists.org/content/141/7/1572.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garric L, Ronsin B, Roussigné M, Booton S, Gamse JT, Dufourcq P, Blader P. Pitx2c ensures habenular asymmetry by restricting parapineal cell number. Development. 2014 Mar 5. [Epub ahead of print].

Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity

Authors:
Nabti I, Marangos P, Bormann J, Kudo NR, Carroll J
Citation:
JCB. 2014;204(6):891-900. doi:10.1083/jcb.201305049
Epub:
Not Epub
Abstract:
Female meiosis is driven by the activities of two major kinases, cyclin-dependent kinase 1 (Cdk1) and mitogen-activated protein...
Link:
http://jcb.rupress.org/content/204/6/891.abstract
Citation Extract:
Nabti I, Marangos P, Bormann J, Kudo NR, Carroll J. Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity. JCB. 2014;204(6):891-900. doi:10.1083/jcb.201305049.

Role of the Amino Terminus in Voltage Gating and Junctional Rectification of Shaking B Innexins

Authors:
Marks WD, Skerrett IM
Citation:
J Neurophysiol. 2013 Dec 31. [Epub ahead of print]
Epub:
Yes
Abstract:
Rectifying electrical synapses are rare gap junctions that favor transmission of signals in one direction. Such synapses have...
Link:
http://jn.physiology.org/content/111/6/1383
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Marks WD, Skerrett IM. Role of the Amino Terminus in Voltage Gating and Junctional Rectification of Shaking B Innexins. J Neurophysiol. 2013 Dec 31. [Epub ahead of print].

Coexpression of auxiliary Kvβ2 subunits with Kv1.1 channels is required for developmental acquisition of unique firing properties of zebrafish Mauthner cells

Authors:
Watanabe T, Shimazaki T, Mishiro A, Suzuki T, Hirata H, Tanimoto M, Oda Y
Citation:
J Neurophysiol. 2013 Dec 11. [Epub ahead of print]
Epub:
Yes
Abstract:
Each neuron possesses a unique firing property, which is largely attributed to heterogeneity in the composition of voltage-...
Link:
http://jn.physiology.org/content/111/6/1153
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Watanabe T, Shimazaki T, Mishiro A, Suzuki T, Hirata H, Tanimoto M, Oda Y. Coexpression of auxiliary Kvβ2 subunits with Kv1.1 channels is required for developmental acquisition of unique firing properties of zebrafish Mauthner cells. J Neurophysiol. 2013 Dec 11. [Epub ahead of print].

The nuclear pore complex function of Sec13 is required for cell survival during retinal development

Authors:
Niu X, Hong J, Zheng X, Melville DB, Knapik EW, Meng A, Peng J
Citation:
J Biol Chem. 2014 Mar 13. [Epub ahead of print]
Epub:
Yes
Abstract:
Sec13 is a dual function protein, being a core component of both the COPII coat, which mediates protein trafficking from the...
Link:
http://www.jbc.org/content/early/2014/03/11/jbc.M114.547190.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Niu X, Hong J, Zheng X, Melville DB, Knapik EW, Meng A, Peng J. The nuclear pore complex function of Sec13 is required for cell survival during retinal development. J Biol Chem. 2014 Mar 13. [Epub ahead of print].

Modulation of the Secretory Pathway Rescues Zebrafish Polycystic Kidney Disease Pathology

Authors:
Le Corre S, Eyre D, Drummond IA
Citation:
J Am Soc Nephrol. 2014 Mar 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in polycystin 1 and polycystin 2 are responsible for autosomal dominant polycystic kidney disease, the most common...
Link:
http://jasn.asnjournals.org/content/early/2014/03/11/ASN.2013101060.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le Corre S, Eyre D, Drummond IA. Modulation of the Secretory Pathway Rescues Zebrafish Polycystic Kidney Disease Pathology. J Am Soc Nephrol. 2014 Mar 13. [Epub ahead of print].

Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Δ7 Mouse Model Phenotype

Authors:
Nizzardo N, Simone C, Salani S, Ruepp M-D, Rizzo F, Ruggieri M, Zanetta C, Brajkovic S, Moulton HM, Müehlemann O, Bresolin N, Comi GP, Corti S
Citation:
Clin Therap. 2014. 36(3):340-56. doi:10.1016/j.clinthera.2014.02.004
Epub:
Not Epub
Abstract:
Background: Spinal muscular atrophy (SMA) is a fatal motor neuron disease of childhood that is caused by mutations in the SMN1...
Link:
http://www.sciencedirect.com/science/article/pii/S0149291814000733
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse SMA model
Citation Extract:
Nizzardo N, Simone C, Salani S, Ruepp M-D, Rizzo F, Ruggieri M, Zanetta C, Brajkovic S, Moulton HM, Müehlemann O, Bresolin N, Comi GP, Corti S. Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Δ7 Mouse Model Phenotype. Clin Therap. 2014. 36(3):340-56. doi:10.1016/j.clinthera.2014.02.004.

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