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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Construction of a Vertebrate Embryo from Two Opposing Morphogen Gradients

Authors:
Xu P-F, Houssin N, Ferri-Lagneau KF, Thisse B, Thisse C
Citation:
Science. 2014:344(6179):87-9. doi:10.1126/science.1248252
Epub:
Not Epub
Abstract:
Development of vertebrate embryos involves tightly regulated molecular and cellular processes that progressively instruct...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu P-F, Houssin N, Ferri-Lagneau KF, Thisse B, Thisse C. Construction of a Vertebrate Embryo from Two Opposing Morphogen Gradients. Science. 2014:344(6179):87-9. doi:10.1126/science.1248252.

Mitotic Position and Morphology of Committed Precursor Cells in the Zebrafish Retina Adapt to Architectural Changes upon Tissue Maturation

Authors:
Weber IP, Ramos AP, Strzyz PJ, Leung LC, Young S, Nordenemail C
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.03.014
Epub:
Yes
Abstract:
The development of complex neuronal tissues like the vertebrate retina requires the tight orchestration of cell proliferation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weber IP, Ramos AP, Strzyz PJ, Leung LC, Young S, Nordenemail C. Mitotic Position and Morphology of Committed Precursor Cells in the Zebrafish Retina Adapt to Architectural Changes upon Tissue Maturation. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.03.014.

A genome-wide association study of the human metabolome in a community-based cohort

Authors:
Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE
Citation:
Cell Metab. 2013 Jul 2;18(1):130-43. doi: 10.1016/j.cmet.2013.06.013
Epub:
Not Epub
Abstract:
Because metabolites are hypothesized to play key roles as markers and effectors of cardiometabolic diseases, recent studies...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 2;18(1):130-43. doi: 10.1016/j.cmet.2013.06.013.

Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes

Authors:
Renzi A, Mancinelli R, Onori P, Franchitto A, Alpini G, Glaser S, Gaudio E
Citation:
Hepatobiliary Surg Nutr. 2014;3(1):4-10. doi:10.3978/j.issn.2304-3881.2014.01.02
Epub:
Not Epub
Abstract:
Background and aims: Reduction of biliary serotonin N-acetyltransferase (AANAT) expression and melatonin administration/...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Renzi A, Mancinelli R, Onori P, Franchitto A, Alpini G, Glaser S, Gaudio E. Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes. Hepatobiliary Surg Nutr. 2014;3(1):4-10. doi:10.3978/j.issn.2304-3881.2014.01.02.

Expression and localization of Rdd proteins in Xenopus embryo

Authors:
Lim JC, Kurihara S, Tamaki R, Mashima Y, Maéno M
Citation:
Anat Cell Biol. 2014;47(1):18-27. doi:10.5115/acb.2014.47.1.18
Epub:
Not Epub
Abstract:
The previous study has shown that repeated D domain-like (Rdd) proteins, a group of novel secretory proteins consisting of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lim JC, Kurihara S, Tamaki R, Mashima Y, Maéno M. Expression and localization of Rdd proteins in Xenopus embryo. Anat Cell Biol. 2014;47(1):18-27. doi:10.5115/acb.2014.47.1.18.

Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer

Authors:
Ding H, Helguera G, Rodríguez JA, Markman J, Luria-Pérez R, Gangalum P, Portilla-Arias J, Inoue S, Daniels-Wells TR, Black K, Holler E, Penichet ML, Ljubimova JY
Citation:
J Control Release. 2013 Nov 10;171(3):322-9. doi: 10.1016/j.jconrel.2013.06.001. Epub 2013 Jun 12
Epub:
Not Epub
Abstract:
Breast cancer remains the second leading cause of cancer death among women in the United States. Breast cancer prognosis is...
Delivery Method:
nanoconjugate
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Ding H, Helguera G, Rodríguez JA, Markman J, Luria-Pérez R, Gangalum P, Portilla-Arias J, Inoue S, Daniels-Wells TR, Black K, Holler E, Penichet ML, Ljubimova JY. Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer. J Control Release. 2013 Nov 10;171(3):322-9. doi: 10.1016/j.jconrel.2013.06.001. Epub 2013 Jun 12.

Investigation of zebrafish homologues to specifically upregulated TUFs in cardiomyocytes derived from murine ES cells

Authors:
Niemann R, Doss X, Winkler J, Chen S, Gajewski M, Hescheler J, Sachinidis A
Citation:
J Stem Cells Regen Med. 2010;6(2):83
Epub:
Not Epub
Abstract:
Heart failure due to loss of functional cardiomyocytes is one of the most frequent cardiovascular diseases. Understanding the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Niemann R, Doss X, Winkler J, Chen S, Gajewski M, Hescheler J, Sachinidis A. Investigation of zebrafish homologues to specifically upregulated TUFs in cardiomyocytes derived from murine ES cells. J Stem Cells Regen Med. 2010;6(2):83.

Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators

Authors:
Liu YP, Tsai I-C, Morleo M, Oh EC, Leitch CC, Massa F, Lee B-H, Parker DS, Finley D, Zaghloul NA, Franco B, Katsanis NK
Citation:
J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71898
Epub:
Not Epub
Abstract:
Cilia are critical mediators of paracrine signaling; however, it is unknown whether proteins that contribute to ciliopathies...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu YP, Tsai I-C, Morleo M, Oh EC, Leitch CC, Massa F, Lee B-H, Parker DS, Finley D, Zaghloul NA, Franco B, Katsanis NK. Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71898.

Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations

Authors:
Russell MR, Raeker MO, Geisler SB, Thomas PE, Simmons TA, Bernat JA, Thorsson T, Innis JW
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu144
Epub:
Yes
Abstract:
Recurrent 2q13 deletion syndrome is associated with incompletely penetrant severe cardiac defects and craniofacial anomalies....
Organism or Cell Type:
zebrafish
Citation Extract:
Russell MR, Raeker MO, Geisler SB, Thomas PE, Simmons TA, Bernat JA, Thorsson T, Innis JW. Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu144.

A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles

Authors:
Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A
Citation:
Development. 2014 Apr;141(7):1526-33. doi: 10.1242/dev.102343. Epub 2014 Mar 5
Epub:
Not Epub
Abstract:
The embryonic skin of Xenopus tadpoles serves as an experimental model system for mucociliary epithelia (MCE) such as the human...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A. A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles. Development. 2014 Apr;141(7):1526-33. doi: 10.1242/dev.102343. Epub 2014 Mar 5.

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