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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney

Authors:
Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O
Citation:
Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6335-40. doi: 10.1073/pnas.1320577111
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are major posttranscriptional regulators of a wide variety of biological processes. However, redundancy...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O. MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6335-40. doi: 10.1073/pnas.1320577111.

Near-Infrared-Light-Based Nano-Platform Boosts Endosomal Escape and Controls Gene Knockdown in Vivo

Authors:
Jayakumar MK, Bansal A, Huang K, Yao R, Li BN, Zhang Y
Citation:
ACS Nano. 2014 Apr 14. [Epub ahead of print]
Epub:
Yes
Abstract:
Current nanoparticle-based gene delivery techniques face two major limitations, namely, endosomal degradation and poor...
Delivery Method:
nanoparticle
Organism or Cell Type:
mouse
Citation Extract:
Jayakumar MK, Bansal A, Huang K, Yao R, Li BN, Zhang Y. Near-Infrared-Light-Based Nano-Platform Boosts Endosomal Escape and Controls Gene Knockdown in Vivo. ACS Nano. 2014 Apr 14. [Epub ahead of print].

Thymosin Beta4 Regulates Cardiac Valve Formation Via Endothelial-Mesenchymal Transformation in Zebrafish Embryos

Authors:
Shin SH, Lee S, Bae JS, Jee JG, Cha HJ, Lee YM
Citation:
Mol Cells. 2014 Apr 8. doi: 10.14348/molcells.2014.0003. [Epub ahead of print]
Epub:
Yes
Abstract:
Thymosin beta4 (TB4) has multiple functions in cellular response in processes as diverse as embryonic organ development and the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shin SH, Lee S, Bae JS, Jee JG, Cha HJ, Lee YM . Thymosin Beta4 Regulates Cardiac Valve Formation Via Endothelial-Mesenchymal Transformation in Zebrafish Embryos. Mol Cells. 2014 Apr 8. doi: 10.14348/molcells.2014.0003. [Epub ahead of print].

Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice

Authors:
Gao X, Zhao J, Han G, Zhang Y, Dong X, Cao L, Wang Q, Moulton HM, Yin H
Citation:
Mol Ther. 2014 Apr 15. doi: 10.1038/mt.2014.63. [Epub ahead of print]
Epub:
Yes
Abstract:
Antisense oligonucleotide (AO) - mediated splice correction therapy for Duchenne muscular dystrophy (DMD) has shown huge...
Delivery Method:
peptide-linked
Organism or Cell Type:
mdx mice
Citation Extract:
Gao X, Zhao J, Han G, Zhang Y, Dong X, Cao L, Wang Q, Moulton HM, Yin H. Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice. Mol Ther. 2014 Apr 15. doi: 10.1038/mt.2014.63. [Epub ahead of print].

Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR

Authors:
Kilari S, Remadevi I, Zhao B, Pan J, Miao R, Ramchandran R, North PE, You M, Rahimi N, Wilkinson GA
Citation:
J Biol Chem. 2013 Apr 12;288(15):10265-74. doi: 10.1074/jbc.M112.413542. Epub 2013 Feb 7
Epub:
Not Epub
Abstract:
The endothelial cell-specific chemotaxis receptor (ECSCR) is a cell-surface protein selectively expressed by endothelial cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kilari S, Remadevi I, Zhao B, Pan J, Miao R, Ramchandran R, North PE, You M, Rahimi N, Wilkinson GA. Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR. J Biol Chem. 2013 Apr 12;288(15):10265-74. doi: 10.1074/jbc.M112.413542. Epub 2013 Feb 7.

Alk3/Alk3b and Smad5 Mediate BMP Signaling during Lymphatic Development in Zebrafish

Authors:
Kim JD, Kim J
Citation:
Mol Cells. 2014 Mar 31;37(3):270-4. doi: 10.14348/molcells.2014.0005. Epub 2014 Mar 6
Epub:
Not Epub
Abstract:
Lymphatic vessels are essential to regulate interstitial fluid homeostasis and diverse immune responses. A number of crucial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JD, Kim J. Alk3/Alk3b and Smad5 Mediate BMP Signaling during Lymphatic Development in Zebrafish. Mol Cells. 2014 Mar 31;37(3):270-4. doi: 10.14348/molcells.2014.0005. Epub 2014 Mar 6.

PV.1 Suppresses the Expression of FoxD5b during Neural Induction in Xenopus Embryos

Authors:
Yoon J, Kim JH, Kim SC, Park JB, Lee JY, Kim J
Citation:
Mol Cells. 2014 Mar 31;37(3):220-5. doi: 10.14348/molcells.2014.2302. Epub 2014 Mar 6
Epub:
Not Epub
Abstract:
Suppression of bone morphogenetic protein (BMP) signaling induces neural induction in the ectoderm of developing embryos. BMP...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon J, Kim JH, Kim SC, Park JB, Lee JY, Kim J. PV.1 Suppresses the Expression of FoxD5b during Neural Induction in Xenopus Embryos. Mol Cells. 2014 Mar 31;37(3):220-5. doi: 10.14348/molcells.2014.2302. Epub 2014 Mar 6.

The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage

Authors:
Peter IS, Davidson EH
Citation:
Dev Biol. 2010 Apr 15;340(2):188-99. doi: 10.1016/j.ydbio.2009.10.037. Epub 2009 Nov 3
Epub:
Not Epub
Abstract:
As the result of early specification processes, sea urchin embryos eventually form various mesodermal cell lineages and a gut...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Peter IS, Davidson EH. The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage. Dev Biol. 2010 Apr 15;340(2):188-99. doi: 10.1016/j.ydbio.2009.10.037. Epub 2009 Nov 3.

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance

Authors:
Schulz Y, Wehner P, Opitz L, Salinas-Riester G, Bongers EMHF, van Ravenswaaij-Arts CMA, Wincent J, Schoumans J, Kohlhase J, Borchers A, Pauli S
Citation:
Hum Genet. 2014;[Epub ahead of print] doi:10.1007/s00439-014-1444-2
Epub:
Yes
Abstract:
Heterozygous loss of function mutations in CHD7 (chromodomain helicase DNA-binding protein 7) lead to CHARGE syndrome, a...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schulz Y, Wehner P, Opitz L, Salinas-Riester G, Bongers EMHF, van Ravenswaaij-Arts CMA, Wincent J, Schoumans J, Kohlhase J, Borchers A, Pauli S. CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance. Hum Genet. 2014;[Epub ahead of print] doi:10.1007/s00439-014-1444-2.

Spinal Muscular Atrophy Phenotype Is Ameliorated Either By SMN Increase Or Modulation Of Secondary Cell Death Events With RNA Therapy (S56.006)

Authors:
Riboldi G, Nizzardo M, Simone C, Rizzo F, Ruggieri M, Pagliarani S, Ulzi G, Salani S, DalMas A, Bucchia M, Frattini E, Stuppia G, Magri F, Bresolin N, Pagani F, Comi G, Corti S
Citation:
Neurology. 2014;82(10):Supplement S56.006
Epub:
Not Epub
Abstract:
OBJECTIVE: The aim of the study was to develop therapeutic strategies based on RNA modulation for Spinal Muscular Atrophy (SMA...
Organism or Cell Type:
cell culture: SMA motor neurons
Citation Extract:
Riboldi G, Nizzardo M, Simone C, Rizzo F, Ruggieri M, Pagliarani S, Ulzi G, Salani S, DalMas A, Bucchia M, Frattini E, Stuppia G, Magri F, Bresolin N, Pagani F, Comi G, Corti S. Spinal Muscular Atrophy Phenotype Is Ameliorated Either By SMN Increase Or Modulation Of Secondary Cell Death Events With RNA Therapy (S56.006). Neurology. 2014;82(10):Supplement S56.006 .

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