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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Reverse engineering validation using a benchmark synthetic gene circuit in human cells
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Citation:
ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28 Epub:
Not Epub Abstract:
Multicomponent biological networks are often understood incompletely, in large part due to the lack of reliable and robust... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Kang T, White JT, Xie Z, Benenson Y, Sontag E, Bleris L. Reverse engineering validation using a benchmark synthetic gene circuit in human cells. ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28. |
Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation
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Citation:
Hum Mol Genet. 2013 May 15;22(10):1924-39. doi: 10.1093/hmg/ddt031. Epub 2013 Feb 5 Epub:
Not Epub Abstract:
Mutations in PKD1 (85%) or PKD2 (15%) account for almost all cases of autosomal dominant polycystic kidney disease (ADPKD). The... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Streets AJ, Wessely O, Peters DJ, Ong AC. Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. Hum Mol Genet. 2013 May 15;22(10):1924-39. doi: 10.1093/hmg/ddt031. Epub 2013 Feb 5. |
The Giardia cell cycle progresses independently of the anaphase-promoting complex
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Citation:
J Cell Sci. 2013 May 15;126(Pt 10):2246-55. doi: 10.1242/jcs.121632. Epub 2013 Mar 22 Epub:
Not Epub Abstract:
Most cell cycle regulation research has been conducted in model organisms representing a very small part of the eukaryotic... Delivery Method:
electroporation Organism or Cell Type:
Giardia intestinalis Citation Extract: Gourguechon S, Holt LJ, Cande WZ. The Giardia cell cycle progresses independently of the anaphase-promoting complex. J Cell Sci. 2013 May 15;126(Pt 10):2246-55. doi: 10.1242/jcs.121632. Epub 2013 Mar 22. |
Crosstalk between planar cell polarity signaling and miR-8 control of NHERF1-mediated actin reorganization
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Citation:
Cell Cycle. 2010 Jan 15;9(2):235-7. Epub 2010 Jan 26 Epub:
Not Epub Abstract:
The response to osmotic stress in developing zebrafish embryos requires proper apical patterning and trafficking of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Flynt AS, Patton JG. Crosstalk between planar cell polarity signaling and miR-8 control of NHERF1-mediated actin reorganization. Cell Cycle. 2010 Jan 15;9(2):235-7. Epub 2010 Jan 26. |
Basal body proteins regulate Notch signaling through endosomal trafficking
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Citation:
J Cell Sci. 2014 Jun 1;127(Pt 11):2407-19. doi: 10.1242/jcs.130344. Epub 2014 Mar 28 Epub:
Not Epub Abstract:
Proteins associated with primary cilia and basal bodies mediate numerous signaling pathways, but little is known about their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Leitch CC, Lodh S, Prieto-Echagüe V, Badano JL, Zaghloul NA. Basal body proteins regulate Notch signaling through endosomal trafficking. J Cell Sci. 2014 Jun 1;127(Pt 11):2407-19. doi: 10.1242/jcs.130344. Epub 2014 Mar 28. |
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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Citation:
J Vis Exp. 2014;(88):e50668. doi:10.3791/50668 Epub:
Not Epub Abstract:
Tumors with similar grade and morphology often respond differently to the same treatment because of variations in molecular... Link:
Delivery Method:
nanoparticle Organism or Cell Type:
mice Citation Extract: Ljubimova JY, Ding H, Portilla-Arias J, Patil R, Gangalum PR, Chesnokova A, Inoue S, Rekechenetskiy A, Nassoura T, Black KL, Holler E. Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?. J Vis Exp. 2014;(88):e50668. doi:10.3791/50668. |
Possible Role of p38 MAPK-MNK1-EMI2 Cascade in Metaphase-II Arrest of Mouse Oocytes
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Citation:
Biol Reprod. 2014;[Epub ahead of print] doi:10.1095/biolreprod.113.116962 Epub:
Not Epub Abstract:
The Mos-MAPK signaling pathway involving the Mos-MEK1/2-ERK1/2-RSK1/2/3 or MSK1-EMI2 cascade is directly linked to metaphase-II... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Miyagaki Y, Kanemori Y, Tanaka F, Baba T. Possible Role of p38 MAPK-MNK1-EMI2 Cascade in Metaphase-II Arrest of Mouse Oocytes. Biol Reprod. 2014;[Epub ahead of print] doi:10.1095/biolreprod.113.116962 . |
The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLP-MYD88 to Authophagic Defense
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Citation:
Cell Host Microbe. 2014;(15)6:753-67. doi:10.1016/j.chom.2014.05.005 Epub:
Not Epub Abstract:
Autophagy is an important defense mechanism against mycobacteria, the causative agents of tuberculosis. The molecular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van der Vaart M, Korbee CJ, Lamers GEM, Tengeler AC, Hosseini R, Haks MC, Ottenhoff THM, Spaink HP, Meijeremail AH. The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLP-MYD88 to Authophagic Defense. Cell Host Microbe. 2014;(15)6:753-67. doi:10.1016/j.chom.2014.05.005. |
Reverse Genetic Morpholino Approach Using Cardiac Ventricular Injection to Transfect Multiple Difficult-to-target Tissues in the Zebrafish Larva
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Citation:
J Vis Exp. 2014;88:e51595 doi:10.3791/51595 Epub:
Not Epub Abstract:
The zebrafish is an important model to understand the cell and molecular biology of organ and appendage regeneration. However,... Delivery Method:
injection Organism or Cell Type:
zebrafish Citation Extract: Konantz J, Antos CL. Reverse Genetic Morpholino Approach Using Cardiac Ventricular Injection to Transfect Multiple Difficult-to-target Tissues in the Zebrafish Larva. J Vis Exp. 2014;88:e51595 doi:10.3791/51595. |
R-Spondin 3 Regulates Dorsoventral and Anteroposterior Patterning by Antagonizing Wnt/β-Catenin Signaling in Zebrafish Embryos
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Citation:
PLoS One. 2014 Jun 11;9(6):e99514. doi: 10.1371/journal.pone.0099514. eCollection 2014 Epub:
Not Epub Abstract:
The Wnt/β-catenin or canonical Wnt signaling pathway plays fundamental roles in early development and in maintaining adult... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rong X, Chen C, Zhou P, Zhou Y, Li Y, Lu L, Liu Y, Zhou J, Duan C. R-Spondin 3 Regulates Dorsoventral and Anteroposterior Patterning by Antagonizing Wnt/β-Catenin Signaling in Zebrafish Embryos. PLoS One. 2014 Jun 11;9(6):e99514. doi: 10.1371/journal.pone.0099514. eCollection 2014. |