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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish

Authors:
Zhang S, Xu M, Huang J, Tang L, Zhang Y, Wu J, Lin S, Wang H
Citation:
Dis Model Mech. 2014 Mar 20. [Epub ahead of print]
Epub:
Yes
Abstract:
Using a zebrafish model for hepatoerythropoietic porphyria (HEP), we found a new mechanism underlying heme regulation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang S, Xu M, Huang J, Tang L, Zhang Y, Wu J, Lin S, Wang H. Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish. Dis Model Mech. 2014 Mar 20. [Epub ahead of print].

Knock-Down DHDDS Expression Induces Photoreceptor Degeneration in Zebrafish

Authors:
Wen R, Dallman JE, Li Y, Züchner SL, Vance JM, Peričak-Vance MA, Lam BL
Citation:
Adv Exp Med Biol. 2014;801:543-50. doi: 10.1007/978-1-4614-3209-8_69
Epub:
Not Epub
Abstract:
A mutation in the dehydrodolichol diphosphate synthase (DHDDS) was recently identified as the cause of a subtype of recessive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wen R, Dallman JE, Li Y, Züchner SL, Vance JM, Peričak-Vance MA, Lam BL. Knock-Down DHDDS Expression Induces Photoreceptor Degeneration in Zebrafish. Adv Exp Med Biol. 2014;801:543-50. doi: 10.1007/978-1-4614-3209-8_69.

In vitro Correction of a Novel Splicing Alteration in the BTK Gene by Using Antisense Morpholino Oligonucleotides

Authors:
Rattanachartnarong N, Tongkobpetch S, Chatchatee P, Daengsuwan T, Ittiwut C, Suphapeetiporn K, Shotelersuk V
Citation:
Arch Immunol Ther Exp (Warsz). 2014 Mar 23. [Epub ahead of print]
Epub:
Yes
Abstract:
A novel sequence variant, c.240+109C>A, in the Bruton's tyrosine kinase (BTK) gene was identified in a patient with X-...
Organism or Cell Type:
Cell culture: human peripheral blood mononuclear cells
Citation Extract:
Rattanachartnarong N, Tongkobpetch S, Chatchatee P, Daengsuwan T, Ittiwut C, Suphapeetiporn K, Shotelersuk V. In vitro Correction of a Novel Splicing Alteration in the BTK Gene by Using Antisense Morpholino Oligonucleotides. Arch Immunol Ther Exp (Warsz). 2014 Mar 23. [Epub ahead of print].

Arginine Decarboxylase and Agmatinase: An Alternative Pathway for De Novo Biosynthesis of Polyamines for Development of Mammalian Conceptuses

Authors:
Wang X, Ying W, Dunlap KA, Lin G, Satterfield MC, Burghardt RC, Wu G, Bazer FW
Citation:
Biol Reprod. 2014 Mar 19. [Epub ahead of print]
Epub:
Yes
Abstract:
Ornithine decarboxylase (ODC1) is considered the rate-controlling enzyme for the classical de novo biosynthesis of polyamines (...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Ovis aries
Citation Extract:
Wang X, Ying W, Dunlap KA, Lin G, Satterfield MC, Burghardt RC, Wu G, Bazer FW. Arginine Decarboxylase and Agmatinase: An Alternative Pathway for De Novo Biosynthesis of Polyamines for Development of Mammalian Conceptuses. Biol Reprod. 2014 Mar 19. [Epub ahead of print].

Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis

Authors:
Butterfield RJ, Stevenson TJ, Xing L, Newcomb TM, Nelson B, Zeng W, Li X, Lu HM, Lu H, Farwell Gonzalez KD, Wei JP, Chao EC, Prior TW, Snyder PJ, Bonkowsky JL, Swoboda KJ
Citation:
Neurology. 2014 Mar 19. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: We describe a novel congenital motor neuron disease with early demise due to respiratory insufficiency with clinical...
Organism or Cell Type:
zebrafish
Citation Extract:
Butterfield RJ, Stevenson TJ, Xing L, Newcomb TM, Nelson B, Zeng W, Li X, Lu HM, Lu H, Farwell Gonzalez KD, Wei JP, Chao EC, Prior TW, Snyder PJ, Bonkowsky JL, Swoboda KJ. Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. Neurology. 2014 Mar 19. [Epub ahead of print].

A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis

Authors:
Dubaissi E, Rousseau K, Lea R, Soto X, Nardeosingh S, Schweickert A, Amaya E, Thornton DJ, Papalopulu N
Citation:
Development. 2014 Mar 5. [Epub ahead of print]
Epub:
Yes
Abstract:
The larval epidermis of Xenopus is a bilayered epithelium, which is an excellent model system for the study of the development...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Dubaissi E, Rousseau K, Lea R, Soto X, Nardeosingh S, Schweickert A, Amaya E, Thornton DJ, Papalopulu N. A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis. Development. 2014 Mar 5. [Epub ahead of print].

Tbx1 regulates the development of zebrafish neural crest cells by retinoic acid signaling

Authors:
Wang W, Zhang LF, Gui YH, Hu JY, Song HY
Citation:
Chin Med J (Engl). 2013 Dec;126(23):4583-4
Epub:
Not Epub
Abstract:
The TBX1 gene is considered to be the most important gene in the aetiology of DiGeorge syndrome (DGS). DGS is a human disorder...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang W, Zhang LF, Gui YH, Hu JY, Song HY. Tbx1 regulates the development of zebrafish neural crest cells by retinoic acid signaling. Chin Med J (Engl). 2013 Dec;126(23):4583-4.

Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers

Authors:
Edlund RK, Ohyama T, Kantarci H, Riley BB, Groves AK
Citation:
Dev Biol. 2014;[Epub ahead of print] doi:10.1016/j.ydbio.2014.03.004
Epub:
Yes
Abstract:
The bones of the vertebrate face develop from transient embryonic branchial arches that are populated by cranial neural crest...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Edlund RK, Ohyama T, Kantarci H, Riley BB, Groves AK. Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014;[Epub ahead of print] doi:10.1016/j.ydbio.2014.03.004.

Ascl1 as a Novel Player in the Ptf1a Transcriptional Network for GABAergic Cell Specification in the Retina

Authors:
Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M
Citation:
PLoS ONE. 2014;9(3):e92113. doi:10.1371/journal.pone.0092113
Epub:
Not Epub
Abstract:
In contrast with the wealth of data involving bHLH and homeodomain transcription factors in retinal cell type determination,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M. Ascl1 as a Novel Player in the Ptf1a Transcriptional Network for GABAergic Cell Specification in the Retina. PLoS ONE. 2014;9(3):e92113. doi:10.1371/journal.pone.0092113.

Pou5f1/Oct4 Promotes Cell Survival via Direct Activation of mych Expression during Zebrafish Gastrulation

Authors:
Kotkamp K, Kur E, Wendik B, Polok BK, Ben-Dor S, Onichtchouk D, Driever W
Citation:
PLoS ONE. 2014;9(3):e92356. doi:10.1371/journal.pone.0092356
Epub:
Not Epub
Abstract:
Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kotkamp K, Kur E, Wendik B, Polok BK, Ben-Dor S, Onichtchouk D, Driever W. Pou5f1/Oct4 Promotes Cell Survival via Direct Activation of mych Expression during Zebrafish Gastrulation. PLoS ONE. 2014;9(3):e92356. doi:10.1371/journal.pone.0092356.

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