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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Transcription of the SCL/TAL1 interrupting locus (Stil) is required for cell proliferation in adult zebrafish retinas

Authors:
Sun L, Li P, Carr AL, Gorsuch R, Yarka C, Li J, Bartlett M, Pfister D, Hyde DR, Li L
Citation:
J Biol Chem. 2014 Jan 27. [Epub ahead of print]
Epub:
Yes
Abstract:
The human oncogene SCL/TAL1 interrupting locus (Stil) is highly conserved in vertebrate species. Previously, we identified a...
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Li P, Carr AL, Gorsuch R, Yarka C, Li J, Bartlett M, Pfister D, Hyde DR, Li L. Transcription of the SCL/TAL1 interrupting locus (Stil) is required for cell proliferation in adult zebrafish retinas. J Biol Chem. 2014 Jan 27. [Epub ahead of print].

Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes

Authors:
Rosenberg MI, Brent AE, Payre F, Desplan C
Citation:
eLife. 2014;3:e01440 doi:10.7554/eLife.01440
Epub:
Not Epub
Abstract:
Embryonic anterior-posterior patterning is well understood in Drosophila, which uses ‘long germ’ embryogenesis, in which all...
Delivery Method:
microinjection
Organism or Cell Type:
Nasonia vitripennis (wasp)
Citation Extract:
Rosenberg MI, Brent AE, Payre F, Desplan C. Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes. eLife. 2014;3:e01440 doi:10.7554/eLife.01440.

Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome

Authors:
Gong Q, Stump MR, Zhou Z
Citation:
Gene. 2014 Feb 13. pii: S0378-1119(14)00182-6. doi: 10.1016/j.gene.2014.02.012. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The degradation of human ether-a-go-go-related gene (hERG, KCNH2) transcripts containing premature termination codon (PTC)...
Citation Extract:
Gong Q, Stump MR, Zhou Z. Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome. Gene. 2014 Feb 13. pii: S0378-1119(14)00182-6. doi: 10.1016/j.gene.2014.02.012. [Epub ahead of print].

FoxD3 regulates cranial neural crest EMT via downregulation of Tetraspanin18 independent of its functions during neural crest formation

Authors:
Fairchild CL, Conway JP, Schiffmacher AT, Taneyhill LA, Gammill LS
Citation:
Mech Dev. 2014 Feb 27. pii: S0925-4773(14)00011-2. doi: 10.1016/j.mod.2014.02.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The scaffolding protein tetraspanin18 (Tspan18) maintains epithelial cadherin-6B (Cad6B) to antagonize chick cranial neural...
Organism or Cell Type:
chick
Citation Extract:
Fairchild CL, Conway JP, Schiffmacher AT, Taneyhill LA, Gammill LS. FoxD3 regulates cranial neural crest EMT via downregulation of Tetraspanin18 independent of its functions during neural crest formation. Mech Dev. 2014 Feb 27. pii: S0925-4773(14)00011-2. doi: 10.1016/j.mod.2014.02.004. [Epub ahead of print].

A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype

Authors:
Magini P, Pippucci T, Tsai IC, Coppola S, Stellacci E, Bartoletti-Stella A, Turchetti D, Graziano C, Cenacchi G, Neri I, Cordelli DM, Marchiani V, Bergamaschi R, Gasparre G, Neri G, Mazzanti L, Patrizi A, Franzoni E, Romeo G, Bordo D, Tartaglia M, Katsanis N, Seri M
Citation:
Hum Mol Genet. 2014 Feb 26. [Epub ahead of print]
Epub:
Yes
Abstract:
Loss-of-function mutations in PAK3 contribute to non-syndromic X-linked intellectual disability (NS-XLID) by affecting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Magini P, Pippucci T, Tsai IC, Coppola S, Stellacci E, Bartoletti-Stella A, Turchetti D, Graziano C, Cenacchi G, Neri I, Cordelli DM, Marchiani V, Bergamaschi R, Gasparre G, Neri G, Mazzanti L, Patrizi A, Franzoni E, Romeo G, Bordo D, Tartaglia M, Katsanis N, Seri M. A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype. Hum Mol Genet. 2014 Feb 26. [Epub ahead of print].

An α-Smooth Muscle Actin (acta2/αsma) Zebrafish Transgenic Line Marking Vascular Mural Cells and Visceral Smooth Muscle Cells

Authors:
Whitesell TR, Kennedy RM, Carter AD, Rollins E-L, Georgijevic S, Santoro MM, Childs SJ
Citation:
PLoS ONE. 2014;9(3):e90590. doi:10.1371/journal.pone.0090590
Epub:
Not Epub
Abstract:
Mural cells of the vascular system include vascular smooth muscle cells (SMCs) and pericytes whose role is to stabilize and/or...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Whitesell TR, Kennedy RM, Carter AD, Rollins E-L, Georgijevic S, Santoro MM, Childs SJ. An α-Smooth Muscle Actin (acta2/αsma) Zebrafish Transgenic Line Marking Vascular Mural Cells and Visceral Smooth Muscle Cells. PLoS ONE. 2014;9(3):e90590. doi:10.1371/journal.pone.0090590.

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

Authors:
Ishikawa H, Ide T Yagi, T, Jiang X, Hirono M, Sasaki H, Yanagisawa H, Wemmer KA, Stainier DY, Qin H, Kamiya R, Marshall WF
Citation:
eLife 2014;3:e01566. doi:10.7554/eLife.01566
Epub:
Not Epub
Abstract:
Cilia/flagella are assembled and maintained by the process of intraflagellar transport (IFT), a highly conserved mechanism...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ishikawa H, Ide T Yagi, T, Jiang X, Hirono M, Sasaki H, Yanagisawa H, Wemmer KA, Stainier DY, Qin H, Kamiya R, Marshall WF. TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella. eLife 2014;3:e01566. doi:10.7554/eLife.01566 .

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Authors:
Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DL, Hammerschmidt M, Joshi A, Hohenstein P, Morris GE, Parson SH, Skehel PA, Becker T, Robinson IM, Becker CG, Wirth B, Gillingwater TH
Citation:
J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71318
Epub:
Yes
Abstract:
The autosomal recessive neurodegenerative disease spinal muscular atrophy (SMA) results from low levels of survival motor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DL, Hammerschmidt M, Joshi A, Hohenstein P, Morris GE, Parson SH, Skehel PA, Becker T, Robinson IM, Becker CG, Wirth B, Gillingwater TH. Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71318 .

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

Authors:
Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM
Citation:
Development. 2014 Feb 12. [Epub ahead of print]
Epub:
Yes
Abstract:
The VEGFC/VEGFR3 signaling pathway is essential for lymphangiogenesis (the formation of lymphatic vessels from pre-existing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM. Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development. 2014 Feb 12. [Epub ahead of print].

Dynamics of Sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring Sulfatase 1

Authors:
Al Oustah A, Danesin C, Khouri-Farah N, Farreny M-A, Escalas N, Cochard P, Glise B, Soula C
Citation:
Development. 2014;141:1392-1403. doi:10.1242/dev.101717
Epub:
Not Epub
Abstract:
In the ventral spinal cord, generation of neuronal and glial cell subtypes is controlled by Sonic hedgehog (Shh). This...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Al Oustah A, Danesin C, Khouri-Farah N, Farreny M-A, Escalas N, Cochard P, Glise B, Soula C. Dynamics of Sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring Sulfatase 1. Development. 2014;141:1392-1403. doi:10.1242/dev.101717 .

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