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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Zebrafish tissue injury causes up-regulation of interleukin-1 and caspase dependent amplification of the inflammatory response

Authors:
Ogryzko NV, Hoggett EE, Solaymani-Kohal S, Tazzyman S, Chico TJ, Renshaw SA, Wilson HL
Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print]
Epub:
Yes
Abstract:
Interleukin-1, the 'gate-keeper' of inflammation, is the apical cytokine in a signalling cascade that drives the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ogryzko NV, Hoggett EE, Solaymani-Kohal S, Tazzyman S, Chico TJ, Renshaw SA, Wilson HL. Zebrafish tissue injury causes up-regulation of interleukin-1 and caspase dependent amplification of the inflammatory response. Dis Model Mech. 2013 Nov 7. [Epub ahead of print].

Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis

Authors:
Manavski Y, Carmona G, Bennewitz K, Tang Z, Zhang F, Sakurai A, Zeiher AM, Gutkind JS, Li X, Kroll J, Dimmeler S, Chavakis E
Citation:
Basic Res Cardiol. 2014 Mar;109(2):404. doi: 10.1007/s00395-014-0404-2. Epub 2014 Feb 13.
Epub:
Not Epub
Abstract:
β1-Integrins are essential for angiogenesis. The mechanisms regulating integrin function in endothelial cells (EC) and their...
Organism or Cell Type:
zebrafish
Citation Extract:
Manavski Y, Carmona G, Bennewitz K, Tang Z, Zhang F, Sakurai A, Zeiher AM, Gutkind JS, Li X, Kroll J, Dimmeler S, Chavakis E. Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis. Basic Res Cardiol. 2014 Mar;109(2):404. doi: 10.1007/s00395-014-0404-2. Epub 2014 Feb 13..

Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway

Authors:
Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.028
Epub:
Yes
Abstract:
The mechanisms dictating whether a cell proliferates or differentiates have undergone intense scrutiny, but they remain poorly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF. Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.028.

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

Authors:
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF
Citation:
Science. 2014 Jan 9. [Epub ahead of print] doi:0.1126/science.1248636
Epub:
Yes
Abstract:
It has been assumed that most, if not all, signals regulating early development have been identified. Contrary to this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF. Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors. Science. 2014 Jan 9. [Epub ahead of print] doi:0.1126/science.1248636 .

The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome

Authors:
Chamling X, Seo S, Searby CC, Kim G, Slusarski DC, Sheffield VC
Citation:
PLoS Genet. 2014;10(2):e1004083. doi:10.1371/journal.pgen.1004083
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a well-known ciliopathy with mutations reported in 18 different genes. Most of the protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chamling X, Seo S, Searby CC, Kim G, Slusarski DC, Sheffield VC. The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome. PLoS Genet. 2014;10(2):e1004083. doi:10.1371/journal.pgen.1004083.

VEGFD regulates blood vascular development by modulating SOX18 activity

Authors:
Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M
Citation:
Blood. 2013;123(7):1102-12. doi:10.1182/blood-2013-04-495432
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor-D (VEGFD) is a potent pro-lymphangiogenic molecule during tumor growth and is considered a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M. VEGFD regulates blood vascular development by modulating SOX18 activity. Blood. 2013;123(7):1102-12. doi:10.1182/blood-2013-04-495432.

Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus

Authors:
Shen W, Liu H-H, Schiapparelli L, McClatchy D, He H-Y, Yates JR, Cline HT
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.024
Epub:
Yes
Abstract:
Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to...
Delivery Method:
injected then electroporated
Organism or Cell Type:
Xenopus laevis tadpoles
Citation Extract:
Shen W, Liu H-H, Schiapparelli L, McClatchy D, He H-Y, Yates JR, Cline HT. Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.024 .

The Role of inab in Axon Morphology of an Identified Zebrafish Motoneuron

Authors:
Van Ryswyk L, Simonson L, Eisen JS
Citation:
PLoS ONE. 2014;9(2):e88631. doi:10.1371/journal.pone.0088631
Epub:
Not Epub
Abstract:
The ability of an animal to move and to interact with its environment requires that motoneurons correctly innervate specific...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Ryswyk L, Simonson L, Eisen JS. The Role of inab in Axon Morphology of an Identified Zebrafish Motoneuron. PLoS ONE. 2014;9(2):e88631. doi:10.1371/journal.pone.0088631.

Differential regulation of myosin heavy chains defines new muscle domains in the zebrafish

Authors:
Nord H, Burguiere A-C, Muck J, Nord C, Ahlgren U, von Hofsten J
Citation:
Mol Biol Cell. 2014;[Epub ahead of print] doi:10.1091/mbc.E13-08-0486
Epub:
Not Epub
Abstract:
Numerous muscle lineages are formed during myogenesis, both within the slow- and the fast specific cell groups. In this study,...
Organism or Cell Type:
zebrafish
Citation Extract:
Nord H, Burguiere A-C, Muck J, Nord C, Ahlgren U, von Hofsten J. Differential regulation of myosin heavy chains defines new muscle domains in the zebrafish. Mol Biol Cell. 2014;[Epub ahead of print] doi:10.1091/mbc.E13-08-0486.

Jak/Stat Signaling Stimulates Zebrafish Optic Nerve Regeneration and Overcomes the Inhibitory Actions of Socs3 and Sfpq

Authors:
Elsaeidi F, Bemben MA, Zhao X-F, Goldman D
Citation:
J Neurosci. 2014;34(7):2632-2644. doi:10.1523/JNEUROSCI.3898-13.2014
Epub:
Not Epub
Abstract:
The regenerative failure of mammalian optic axons is partly mediated by Socs3-dependent inhibition of Jak/Stat signaling (Smith...
Delivery Method:
microinjection, Gelfoam at lesion
Organism or Cell Type:
zebrafish
Citation Extract:
Elsaeidi F, Bemben MA, Zhao X-F, Goldman D. Jak/Stat Signaling Stimulates Zebrafish Optic Nerve Regeneration and Overcomes the Inhibitory Actions of Socs3 and Sfpq. J Neurosci. 2014;34(7):2632-2644. doi:10.1523/JNEUROSCI.3898-13.2014.

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