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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Blockade of CD47 mediated CTSS-PAR2 signaling provides a therapeutic target for hepatocellular carcinoma

Authors:
Lee TKW, Cheung VCH, Lu P, Lau EYT, Ma S, Tang KH, Tong M, Lo J, Ng IOL
Citation:
Hepatology. 2014;[Epub ahead of print] doi:10.1002/hep.27070
Epub:
Not Epub
Abstract:
The identification of therapeutic targets against tumor-initiating cells (T-ICs) is a priority in the development of new...
Delivery Method:
intratumoral injection
Organism or Cell Type:
Human xenograft in mice
Citation Extract:
Lee TKW, Cheung VCH, Lu P, Lau EYT, Ma S, Tang KH, Tong M, Lo J, Ng IOL. Blockade of CD47 mediated CTSS-PAR2 signaling provides a therapeutic target for hepatocellular carcinoma. Hepatology. 2014;[Epub ahead of print] doi:10.1002/hep.27070.

Hapln1a Is Required for Connexin43-Dependent Growth and Patterning in the Regenerating Fin Skeleton

Authors:
Govindan J, Iovine MK
Citation:
PLoS ONE. 2014;9(2):e88574. doi:10.1371/journal.pone.0088574
Epub:
Not Epub
Abstract:
Cell-cell communication, facilitating the exchange of small metabolites, ions and second messengers, takes place via aqueous...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Govindan J, Iovine MK. Hapln1a Is Required for Connexin43-Dependent Growth and Patterning in the Regenerating Fin Skeleton. PLoS ONE. 2014;9(2):e88574. doi:10.1371/journal.pone.0088574.

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry

Authors:
Hjeij R, Lindstrand A, Francis R, Zariwala MA, Liu X, Li Y, Damerla R, Dougherty GW, Abouhamed M, Olbrich H, Loges NT, Pennekamp P, Davis EE, Carvalho CM, Pehlivan D, Werner C, Raidt J, Köhler G, Häffner K, Reyes-Mugica M, Lupski JR, Leigh MW, Rosenfeld M, Morgan LC, Knowles MR, Lo CW, Katsanis N, Omran H
Citation:
Am J Hum Genet. 2013 Aug 8;93(2):357-67. doi: 10.1016/j.ajhg.2013.06.009. Epub 2013 Jul 11
Epub:
Not Epub
Abstract:
The motive forces for ciliary movement are generated by large multiprotein complexes referred to as outer dynein arms (ODAs),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hjeij R, Lindstrand A, Francis R, Zariwala MA, Liu X, Li Y, Damerla R, Dougherty GW, Abouhamed M, Olbrich H, Loges NT, Pennekamp P, Davis EE, Carvalho CM, Pehlivan D, Werner C, Raidt J, Köhler G, Häffner K, Reyes-Mugica M, Lupski JR, Leigh MW, Rosenfeld M, Morgan LC, Knowles MR, Lo CW, Katsanis N, Omran H. ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. Am J Hum Genet. 2013 Aug 8;93(2):357-67. doi: 10.1016/j.ajhg.2013.06.009. Epub 2013 Jul 11.

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis

Authors:
White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I
Citation:
Cell Metab. 2013 Feb 5;17(2):261-70. doi: 10.1016/j.cmet.2013.01.005
Epub:
Not Epub
Abstract:
Adult humans have about 25 trillion red blood cells (RBCs) and each second we recycle about five million RBCs by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I. HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. Cell Metab. 2013 Feb 5;17(2):261-70. doi: 10.1016/j.cmet.2013.01.005.

Clock controls angiogenesis

Authors:
Jensen LD, Cao Y
Citation:
Cell Cycle. 2013 Feb 1;12(3):405-8. doi: 10.4161/cc.23596. Epub 2013 Jan 16
Epub:
Not Epub
Abstract:
Circadian rhythms control multiple physiological and pathological processes, including embryonic development in mammals and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jensen LD, Cao Y. Clock controls angiogenesis. Cell Cycle. 2013 Feb 1;12(3):405-8. doi: 10.4161/cc.23596. Epub 2013 Jan 16.

Gene regulatory control in the sea urchin aboral ectoderm: spatial initiation, signaling inputs, and cell fate lockdown

Authors:
Ben-Tabou de-Leon S, Su YH, Lin KT, Li E, Davidson EH
Citation:
Dev Biol. 2013 Feb 1;374(1):245-54. doi: 10.1016/j.ydbio.2012.11.013. Epub 2012 Dec 2
Epub:
Not Epub
Abstract:
The regulation of oral-aboral ectoderm specification in the sea urchin embryo has been extensively studied in recent years. The...
Delivery Method:
microinjection
Organism or Cell Type:
Sea urchin Strongylocentrotus purpuratus
Citation Extract:
Ben-Tabou de-Leon S, Su YH, Lin KT, Li E, Davidson EH. Gene regulatory control in the sea urchin aboral ectoderm: spatial initiation, signaling inputs, and cell fate lockdown. Dev Biol. 2013 Feb 1;374(1):245-54. doi: 10.1016/j.ydbio.2012.11.013. Epub 2012 Dec 2.

Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos

Authors:
van Veenendaal NR, Ulmer B, Boskovski MT, Fang X, Khokha MK, Wendler CC, Blum M, Rivkees SA
Citation:
FASEB J. 2013 Feb;27(2):684-91. doi: 10.1096/fj.12-218073. Epub 2012 Nov 12
Epub:
Not Epub
Abstract:
Antithyroid medications are the preferred therapy for the treatment of Graves' disease during pregnancy. Propylthiouracil...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
van Veenendaal NR, Ulmer B, Boskovski MT, Fang X, Khokha MK, Wendler CC, Blum M, Rivkees SA. Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos. FASEB J. 2013 Feb;27(2):684-91. doi: 10.1096/fj.12-218073. Epub 2012 Nov 12.

A critical role for STIM1 in filopodial calcium entry and axon guidance

Authors:
Shim S, Zheng JQ, Ming GL
Citation:
Mol Brain. 2013 Dec 1;6:51. doi: 10.1186/1756-6606-6-51
Epub:
Not Epub
Abstract:
BACKGROUND: Stromal interaction molecule 1 (STIM1), a Ca2+ sensor in the endoplasmic reticulum, regulates store-operated Ca2+...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Shim S, Zheng JQ, Ming GL. A critical role for STIM1 in filopodial calcium entry and axon guidance. Mol Brain. 2013 Dec 1;6:51. doi: 10.1186/1756-6606-6-51.

Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth

Authors:
Lowery LA, Stout A, Faris AE, Ding L, Baird MA, Davidson MW, Danuser G, Van Vactor D
Citation:
Neural Dev. 2013 Dec 1;8:22. doi: 10.1186/1749-8104-8-22
Epub:
Not Epub
Abstract:
BACKGROUND:Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lowery LA, Stout A, Faris AE, Ding L, Baird MA, Davidson MW, Danuser G, Van Vactor D. Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth. Neural Dev. 2013 Dec 1;8:22. doi: 10.1186/1749-8104-8-22.

Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility

Authors:
Zhao L, Yuan S, Cao Y, Kallakuri S, Li Y, Kishimoto N, DiBella L, Sun Z
Citation:
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12697-702. doi: 10.1073/pnas.1300968110. Epub 2013 Jul 15
Epub:
Not Epub
Abstract:
Primary ciliary dyskinesia (PCD) is an autosomal recessive disease caused by defective cilia motility. The identified PCD genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao L, Yuan S, Cao Y, Kallakuri S, Li Y, Kishimoto N, DiBella L, Sun Z. Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12697-702. doi: 10.1073/pnas.1300968110. Epub 2013 Jul 15.

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