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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Promoter directionality is controlled by U1 snRNP and polyadenylation signals

Authors:
Almada AE, Wu X, Kriz AJ, Burge CB, Sharp PA
Citation:
Nature. 2013 Jul 18;499(7458):360-3. doi: 10.1038/nature12349. Epub 2013 Jun 23
Epub:
Not Epub
Abstract:
Transcription of the mammalian genome is pervasive, but productive transcription outside of protein-coding genes is limited by...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: mouse embryonic stem cells (mESC)
Citation Extract:
Almada AE, Wu X, Kriz AJ, Burge CB, Sharp PA. Promoter directionality is controlled by U1 snRNP and polyadenylation signals. Nature. 2013 Jul 18;499(7458):360-3. doi: 10.1038/nature12349. Epub 2013 Jun 23.

Thyroid hormone and retinoic acid interact to regulate zebrafish craniofacial neural crest development

Authors:
Bohnsack BL, Kahana A
Citation:
Dev Biol. 2013 Jan 15;373(2):300-9. doi: 10.1016/j.ydbio.2012.11.005. Epub 2012 Nov 17
Epub:
Not Epub
Abstract:
Craniofacial and ocular morphogenesis require proper regulation of cranial neural crest migration, proliferation, survival and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bohnsack BL, Kahana A. Thyroid hormone and retinoic acid interact to regulate zebrafish craniofacial neural crest development. Dev Biol. 2013 Jan 15;373(2):300-9. doi: 10.1016/j.ydbio.2012.11.005. Epub 2012 Nov 17.

Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion

Authors:
Minchin JE, Williams VC, Hinits Y, Low S, Tandon P, Fan CM, Rawls JF, Hughes SM
Citation:
Development. 2013 Jul;140(14):2972-84. doi: 10.1242/dev.090050. Epub 2013 Jun 12. Erratum in: Development. 2013 Oct;140(20):4296
Epub:
Not Epub
Abstract:
Striated muscles that enable mouth opening and swallowing during feeding are essential for efficient energy acquisition, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minchin JE, Williams VC, Hinits Y, Low S, Tandon P, Fan CM, Rawls JF, Hughes SM. Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development. 2013 Jul;140(14):2972-84. doi: 10.1242/dev.090050. Epub 2013 Jun 12. Erratum in: Development. 2013 Oct;140(20):4296.

Extraembryonic Signals under the Control of MGA, Max, and Smad4 Are Required for Dorsoventral Patterning

Authors:
Sun Y, Tseng W-C, Fan X, Ball R, Dougan ST
Citation:
Dev Cell. 2014;28(3):322-334
Epub:
Not Epub
Abstract:
In vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducible pattern of cell types upon the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Tseng W-C, Fan X, Ball R, Dougan ST. Extraembryonic Signals under the Control of MGA, Max, and Smad4 Are Required for Dorsoventral Patterning. Dev Cell. 2014;28(3):322-334.

Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation

Authors:
Aboualaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I, Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM
Citation:
Circulation. 2014;129:660-672
Epub:
Not Epub
Abstract:
BACKGROUND: Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aboualaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I, Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM. Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation. Circulation. 2014;129:660-672 .

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia

Authors:
Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T
Citation:
Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011
Epub:
Not Epub
Abstract:
Most patients with acute lymphoblastic leukemia (ALL) fail current treatments highlighting the need for better therapies....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T. Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011.

Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept

Authors:
Arnold WD, Porensky PN, McGovern VL, Iyer CC, Duque S, Li X, Meyer K, Schmelzer L, Kaspar BK, Kolb SJ, Kissel JT, Burghes AH
Citation:
Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44
Epub:
Not Epub
Abstract:
Objective: Preclinical therapies that restore survival motor neuron (SMN) protein levels can dramatically extend survival in...
Delivery Method:
intracerebroventricular injection
Organism or Cell Type:
mouse
Citation Extract:
Arnold WD, Porensky PN, McGovern VL, Iyer CC, Duque S, Li X, Meyer K, Schmelzer L, Kaspar BK, Kolb SJ, Kissel JT, Burghes AH. Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept. Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44.

A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish

Authors:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML
Citation:
Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is an inherited disorder with mutations affecting telomerase or telomeric proteins. DC patients...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML. A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228.

PCP and septins compartmentalize cortical actomyosin to direct collective cell movement

Authors:
Shindo A, Wallingford JB
Citation:
Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126
Epub:
Not Epub
Abstract:
Despite our understanding of actomyosin function in individual migrating cells, we know little about the mechanisms by which...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shindo A, Wallingford JB. PCP and septins compartmentalize cortical actomyosin to direct collective cell movement. Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126.

An essential role for LPA signalling in telencephalon development

Authors:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L
Citation:
Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901
Epub:
Not Epub
Abstract:
Lysophosphatidic acid (LPA) has wide-ranging effects on many different cell types, acting through G-protein-coupled receptors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L. An essential role for LPA signalling in telencephalon development. Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901.

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