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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe’s disease

Authors:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M
Citation:
Biochim Biophys Acta. 2014;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbadis.2014.01.008
Epub:
Yes
Abstract:
The lysosomal hydrolase galactocerebrosidase (GALC) catalyzes the removal of galactose from galactosylceramide and from other...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M. Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe’s disease. Biochim Biophys Acta. 2014;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbadis.2014.01.008.

Expression and Functional Characterization of Smyd1a in Myofibril Organization of Skeletal Muscles

Authors:
Gao J, Li J, Li B-J, Yagil E, Zhang J, Du SJ
Citation:
PLoS ONE. 2014;9(1): e86808. doi:10.1371/journal.pone.0086808
Epub:
Not Epub
Abstract:
Background: Smyd1, the founding member of the Smyd family including Smyd-1, 2, 3, 4 and 5, is a SET and MYND domain containing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao J, Li J, Li B-J, Yagil E, Zhang J, Du SJ. Expression and Functional Characterization of Smyd1a in Myofibril Organization of Skeletal Muscles. PLoS ONE. 2014;9(1): e86808. doi:10.1371/journal.pone.0086808.

Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

Authors:
Agranat-Tamir L, Shomron N, Sperling J, Sperling R
Citation:
Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gkt1413
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are central regulators of gene expression, and a large fraction of them are encoded in introns of RNA...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Agranat-Tamir L, Shomron N, Sperling J, Sperling R. Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome. Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gkt1413 .

Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo

Authors:
Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
Citation:
J Biochem. 2014 Jan 21. [Epub ahead of print]
Epub:
Yes
Abstract:
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are second-generation lysophospholipid mediators that exert...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J. Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. J Biochem. 2014 Jan 21. [Epub ahead of print].

The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor

Authors:
Han H-W, Chou C-M, Chu C-Y, Cheng C-H, Yang C-H, Hung C-C, Hwang P-P, Lee S-J, Liao Y-F, Huang C-J
Citation:
PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345
Epub:
Not Epub
Abstract:
The fish lateral line (LL) is a mechanosensory system closely related to the hearing system of higher vertebrates, and it is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han H-W, Chou C-M, Chu C-Y, Cheng C-H, Yang C-H, Hung C-C, Hwang P-P, Lee S-J, Liao Y-F, Huang C-J. The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor. PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345.

Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis

Authors:
Hu B, Zhang W, Feng X, Ji W, Xie X, Xiao W
Citation:
Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17
Epub:
Not Epub
Abstract:
Studies implicate a potential role for EAF1 in MLL-ELL induced leukemogenesis; however the biological function of EAF1 in this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu B, Zhang W, Feng X, Ji W, Xie X, Xiao W. Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis. Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17.

Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling

Authors:
Rengarajan C, Matzke A, Reiner L, Orian-Rousseau V, Scholpp S
Citation:
PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373
Epub:
Not Epub
Abstract:
Tightly controlled concentration gradients of morphogens provide positional information and thus regulate tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rengarajan C, Matzke A, Reiner L, Orian-Rousseau V, Scholpp S. Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling. PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373.

Autophagy is essential for cardiac morphogenesis during vertebrate development

Authors:
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF
Citation:
Autophagy. 2014 Jan 14;10(4). [Epub ahead of print]
Epub:
Not Epub
Abstract:
Genetic analyses indicate that autophagy, an evolutionarily conserved lysosomal degradation pathway, is essential for...
Organism or Cell Type:
zebrafish
Citation Extract:
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 2014 Jan 14;10(4). [Epub ahead of print].

Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis

Authors:
Žigman M, Laumann-Lipp N, Titus T, Postlethwait J, Moens CB
Citation:
Development. 2014;141:639-649. doi:10.1242/dev.098731
Epub:
Not Epub
Abstract:
Hox genes are classically ascribed to function in patterning the anterior-posterior axis of bilaterian animals; however, their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Žigman M, Laumann-Lipp N, Titus T, Postlethwait J, Moens CB. Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis. Development. 2014;141:639-649. doi:10.1242/dev.098731 .

Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples

Authors:
Gorelick DA, Iwanowicz LR, Hung AL, Blazer VS, Halpern ME
Citation:
Environ Health Perspect. 2014;122(4):356-62 doi:0.1289/ehp.1307329
Epub:
Not Epub
Abstract:
Background: Environmental endocrine disruptors (EED) are exogenous chemicals that mimic endogenous hormones, such as estrogens...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gorelick DA, Iwanowicz LR, Hung AL, Blazer VS, Halpern ME. Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples. Environ Health Perspect. 2014;122(4):356-62 doi:0.1289/ehp.1307329.

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