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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis

Authors:
Blanco-Sánchez B, Clément A, Fierro J Jr, Washbourne P, Westerfield M
Citation:
Dis Model Mech. 2014 May;7(5):547-59. doi: 10.1242/dmm.014068. Epub 2014 Mar 13
Epub:
Not Epub
Abstract:
Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blanco-Sánchez B, Clément A, Fierro J Jr, Washbourne P, Westerfield M. Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis. Dis Model Mech. 2014 May;7(5):547-59. doi: 10.1242/dmm.014068. Epub 2014 Mar 13.

A noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defects

Authors:
Favaro FP, Alvizi L, Zechi-Ceide RM, Bertola D, Felix TM, de Souza J, Raskin S, Twigg SR, Weiner AM, Armas P, Margarit E, Calcaterra NB, Andersen GR, McGowan SJ, Wilkie AO, Richieri-Costa A, de Almeida ML, Passos-Bueno MR
Citation:
Am J Hum Genet. 2014 Jan 2;94(1):120-8. doi: 10.1016/j.ajhg.2013.11.020. Epub 2013 Dec 19
Epub:
Not Epub
Abstract:
Richieri-Costa-Pereira syndrome is an autosomal-recessive acrofacial dysostosis characterized by mandibular median cleft...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Favaro FP, Alvizi L, Zechi-Ceide RM, Bertola D, Felix TM, de Souza J, Raskin S, Twigg SR, Weiner AM, Armas P, Margarit E, Calcaterra NB, Andersen GR, McGowan SJ, Wilkie AO, Richieri-Costa A, de Almeida ML, Passos-Bueno MR. A noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defects. Am J Hum Genet. 2014 Jan 2;94(1):120-8. doi: 10.1016/j.ajhg.2013.11.020. Epub 2013 Dec 19.

Dynamic Expression of Chymotrypsin-Like Elastase 1 Over the Course of Murine Lung Development

Authors:
Liu S, Young SM, Varisco BM
Citation:
Am J Physiol Lung Cell Mol Physiol. 2014 May 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Postnatal lung development requires coordination of three processes-surface area expansion, microvascular growth, and matrix...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice C57BL/6J
Citation Extract:
Liu S, Young SM, Varisco BM. Dynamic Expression of Chymotrypsin-Like Elastase 1 Over the Course of Murine Lung Development. Am J Physiol Lung Cell Mol Physiol. 2014 May 2. [Epub ahead of print].

Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress-Induced Inflammation

Authors:
Candel S, de Oliveira S, López-Muñoz A, García-Moreno D, Espín-Palazón R, Tyrkalska SD, Cayuela ML, Renshaw RA, Corbalán-Vélez R, Vidal-Abarca I, Tsai H-J, Meseguer J, Sepulcre MP, Mulero V
Citation:
PLoS Biol. 2014;12(5):e1001855. doi:10.1371/journal.pbio.1001855
Epub:
Not Epub
Abstract:
TNFα overexpression has been associated with several chronic inflammatory diseases, including psoriasis, lichen planus,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Candel S, de Oliveira S, López-Muñoz A, García-Moreno D, Espín-Palazón R, Tyrkalska SD, Cayuela ML, Renshaw RA, Corbalán-Vélez R, Vidal-Abarca I, Tsai H-J, Meseguer J, Sepulcre MP, Mulero V. Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress-Induced Inflammation. PLoS Biol. 2014;12(5):e1001855. doi:10.1371/journal.pbio.1001855.

Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration

Authors:
Tuttle AM, Hoffman TL, Schilling TF
Citation:
PLoS Biol. 2014;12(5):e1001852. doi:10.1371/journal.pbio.1001852
Epub:
Not Epub
Abstract:
Cell migration requires dynamic regulation of cell-cell signaling and cell adhesion. Both of these processes involve...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tuttle AM, Hoffman TL, Schilling TF. Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration. PLoS Biol. 2014;12(5):e1001852. doi:10.1371/journal.pbio.1001852.

Bucky ball organizes germ plasm assembly in zebrafish

Authors:
Bontems F, Stein A, Marlow F, Lyautey J, Gupta T, Mullins MC, Dosch R
Citation:
Curr Biol. 2009 Mar 10;19(5):414-22. doi: 10.1016/j.cub.2009.01.038. Epub 2009 Feb 26
Epub:
Not Epub
Abstract:
In many animals, gamete formation during embryogenesis is specified by maternal cytoplasmic determinants termed germ plasm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bontems F, Stein A, Marlow F, Lyautey J, Gupta T, Mullins MC, Dosch R. Bucky ball organizes germ plasm assembly in zebrafish. Curr Biol. 2009 Mar 10;19(5):414-22. doi: 10.1016/j.cub.2009.01.038. Epub 2009 Feb 26.

Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus

Authors:
Hett A, West S
Citation:
PLoS ONE. 2014;9(5):e96174. doi:10.1371/journal.pone.0096174
Epub:
Not Epub
Abstract:
Most human pre-mRNAs contain introns that are removed by splicing. Such a complex process needs strict control and regulation...
Delivery Method:
electroporation
Organism or Cell Type:
Cell culture:HeLa
Citation Extract:
Hett A, West S. Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus. PLoS ONE. 2014;9(5):e96174. doi:10.1371/journal.pone.0096174.

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

Authors:
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA
Citation:
Nucleic Acids Res. 2014 May 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Myotonic dystrophy type 1 (DM1) is a dominantly inherited neuromuscular disorder resulting from expression of RNA containing an...
Delivery Method:
injection (mouse), electroporation (C2C12 cells)
Organism or Cell Type:
mouse, cell culture:C2C12 myogenic cells
Citation Extract:
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA. Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects. Nucleic Acids Res. 2014 May 5. [Epub ahead of print].

Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish

Authors:
Chen LT, Liang WX, Chen S, Li RK, Tan JL, Xu PF, Luo LF, Wang L, Yu SH, Meng G, Li KK, Liu TX, Chen Z, Chen SJ
Citation:
Nat Commun. 2014 May 2;5:3811. doi: 10.1038/ncomms4811
Epub:
Not Epub
Abstract:
We previously reported a fusion protein NUP98-IQCG in an acute leukaemia, which functions as an aberrant regulator of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen LT, Liang WX, Chen S, Li RK, Tan JL, Xu PF, Luo LF, Wang L, Yu SH, Meng G, Li KK, Liu TX, Chen Z, Chen SJ. Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish. Nat Commun. 2014 May 2;5:3811. doi: 10.1038/ncomms4811.

The development of zebrafish tendon and ligament progenitors

Authors:
Chen JW, Galloway JL
Citation:
Development. 2014;141:2035-45. doi:10.1242/dev.104067
Epub:
Not Epub
Abstract:
Despite the importance of tendons and ligaments for transmitting movement and providing stability to the musculoskeletal system...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen JW, Galloway JL. The development of zebrafish tendon and ligament progenitors. Development. 2014;141:2035-45. doi:10.1242/dev.104067.

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