You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

Authors:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA
Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print]
Epub:
Yes
Abstract:
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA. Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Dis Model Mech. 2013 Nov 7. [Epub ahead of print].

PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos

Authors:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J
Citation:
BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print]
Epub:
Yes
Abstract:
During Xenopus early development, FGF signaling is involved in mesoderm formation and neurogenesis by modulating various...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J. PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos. BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print].

Differential Skeletal Muscle Proteome of High and Low Active mice

Authors:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT
Citation:
J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Physical inactivity contributes to cardiovascular disease, type II diabetes, obesity and some types of cancer. While the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT. Differential Skeletal Muscle Proteome of High and Low Active mice. J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print].

Expression and function of transcription factor cMyb during cranial neural crest development

Authors:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME
Citation:
Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005
Epub:
Yes
Abstract:
The transcription factor cMyb has well known functions in vertebrate hematopoiesis, but little was known about its distribution...
Organism or Cell Type:
chick
Citation Extract:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005.

The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development

Authors:
Ouchi Y, Yamamoto J, Iwamoto T
Citation:
PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086
Epub:
Not Epub
Abstract:
The Caenorhabditis elegans heterochronic gene pathway, which consists of a set of regulatory genes, plays an important...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouchi Y, Yamamoto J, Iwamoto T. The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development. PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086.

Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis

Authors:
Toruno C, Carbonneau S, Stewart RA, Jette C
Citation:
PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151
Epub:
Not Epub
Abstract:
Ionizing radiation (IR)-induced DNA double-strand breaks trigger an extensive cellular signaling response that involves the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toruno C, Carbonneau S, Stewart RA, Jette C. Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis. PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151.

Antisense suppression of donor splice site mutations in the dystrophin gene transcript

Authors:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD
Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13
Epub:
Not Epub
Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-linked
Organism or Cell Type:
Primary DMD human cells underwent forced myogenesis
Citation Extract:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13.

Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis

Authors:
Dash SN, Lehtonen E, Wasik AA, Schepis A, Paavola J, Panula P, Nelson WJ, Lehtonen S
Citation:
J Cell Sci. 2014;[Epub ahead of print] doi:10.1242/jcs.138495
Epub:
Yes
Abstract:
The conserved septin family of filamentous small GTPases plays important roles in mitosis, cell migration, and cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash SN, Lehtonen E, Wasik AA, Schepis A, Paavola J, Panula P, Nelson WJ, Lehtonen S. Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis. J Cell Sci. 2014;[Epub ahead of print] doi:10.1242/jcs.138495.

A network of epigenetic regulators guides developmental haematopoiesis in vivo

Authors:
Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI
Citation:
Nat Cell Biol. 2013 Dec;15(12):1516-25. doi: 10.1038/ncb2870. Epub 2013 Nov 17
Epub:
Not Epub
Abstract:
The initiation of cellular programs is orchestrated by key transcription factors and chromatin regulators that activate or...
Organism or Cell Type:
zebrafish
Citation Extract:
Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI . A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nat Cell Biol. 2013 Dec;15(12):1516-25. doi: 10.1038/ncb2870. Epub 2013 Nov 17.

Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies

Authors:
Osborn DPS, Roccasecca RM, McMurray F, Hernandez-Hernandez V, Mukherjee S, Barroso I, Stemple D, Cox R, Beales PL, Christou-Salvina S
Citation:
PLoS ONE 2014;9(2):e87662. doi:10.1371/journal.pone.0087662
Epub:
Not Epub
Abstract:
Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Roccasecca RM, McMurray F, Hernandez-Hernandez V, Mukherjee S, Barroso I, Stemple D, Cox R, Beales PL, Christou-Salvina S. Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies. PLoS ONE 2014;9(2):e87662. doi:10.1371/journal.pone.0087662.

Pages