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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition

Authors:
Clay MR, Halloran MC
Citation:
Development 2014 141:2506-2515; doi:10.1242/dev.105551
Epub:
Not Epub
Abstract:
The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Clay MR, Halloran MC. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. Development 2014 141:2506-2515; doi:10.1242/dev.105551.

Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+‐CaMKII‐Regulated Induction of HDAC3

Authors:
Sharifi‐Sanjani M, Shoushtari AH, Quiroz M, Baust J, Sestito SF, Mosher M, Ross M, McTiernan CF, St. Croix CM, Bilonick RA, Champion HC, Isenberg JS
Citation:
J Am Heart Assoc. 2014;3:e000670, originally published June 10, 2014, doi:10.1161/JAHA.113.000670
Epub:
Yes
Abstract:
Background: Left ventricular heart failure (LVHF) remains progressive and fatal and is a formidable health problem because ever...
Delivery Method:
cell bathing in culture, injection in vivo
Organism or Cell Type:
cell culture: rat neonatal cardiac myocytes (RNMC), mice C57BL/6
Citation Extract:
Sharifi‐Sanjani M, Shoushtari AH, Quiroz M, Baust J, Sestito SF, Mosher M, Ross M, McTiernan CF, St. Croix CM, Bilonick RA, Champion HC, Isenberg JS. Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+‐CaMKII‐Regulated Induction of HDAC3. J Am Heart Assoc. 2014;3:e000670, originally published June 10, 2014, doi:10.1161/JAHA.113.000670 .

TLR7 is a key regulator of innate immunity against Japanese Encephalitis Virus infection

Authors:
Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A
Citation:
Neurobiol Dis. 2014 Sep;69:235-47. doi: 10.1016/j.nbd.2014.05.036. Epub 2014 Jun 5.
Epub:
Not Epub
Abstract:
Toll-like receptor 7 (TLR7) known to recognize guanidine-rich ssRNA has been shown to mount vital host defense mechanism...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A. TLR7 is a key regulator of innate immunity against Japanese Encephalitis Virus infection. Neurobiol Dis. 2014 Sep;69:235-47. doi: 10.1016/j.nbd.2014.05.036. Epub 2014 Jun 5..

Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton

Authors:
Dworkina S, Simkin J, Darido C, Partridge DD, Georgy SR, Caddy J, Wilanowski T, Lieschke GJ, Doggett K, Heath JK, Jane SM
Citation:
Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.05.005
Epub:
Yes
Abstract:
Craniofacial development is a highly conserved process that requires complex interactions between neural crest cells (NCCs) and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dworkina S, Simkin J, Darido C, Partridge DD, Georgy SR, Caddy J, Wilanowski T, Lieschke GJ, Doggett K, Heath JK, Jane SM. Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton. Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.05.005.

Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis

Authors:
Ramsbottom SA, Maguire RJ, Fellgett SW, Pownall ME
Citation:
Dev Biol. 2014 Jul 15;391(2):207-18. doi: 10.1016/j.ydbio.2014.04.010. Epub 2014 Apr 24
Epub:
Not Epub
Abstract:
Genetic studies have established that heparan sulphate proteoglycans (HSPGs) are required for signalling by key developmental...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Ramsbottom SA, Maguire RJ, Fellgett SW, Pownall ME. Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis. Dev Biol. 2014 Jul 15;391(2):207-18. doi: 10.1016/j.ydbio.2014.04.010. Epub 2014 Apr 24.

Foxi3 is necessary for the induction of the chick otic placode in response to FGF signaling

Authors:
Khatri SB, Edlund RK, Groves AK
Citation:
Dev Biol. 2014 Jul 15;391(2):158-69. doi: 10.1016/j.ydbio.2014.04.014. Epub 2014 Apr 26
Epub:
Not Epub
Abstract:
Vertebrate cranial sensory organs are derived from region at the border of the anterior neural plate called the pre-placodal...
Organism or Cell Type:
chick
Citation Extract:
Khatri SB, Edlund RK, Groves AK. Foxi3 is necessary for the induction of the chick otic placode in response to FGF signaling. Dev Biol. 2014 Jul 15;391(2):158-69. doi: 10.1016/j.ydbio.2014.04.014. Epub 2014 Apr 26.

Symmetry breakage in the frog Xenopus: Role of Rab11 and the ventral-right blastomere

Authors:
Tingler M, Ott T, Tözser J, Kurz S, Getwan M, Tisler M, Schweickert A, Blum M
Citation:
Genesis. 2014 Mar 2. doi: 10.1002/dvg.22766. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Vertebrates display asymmetric arrangements of inner organs such as heart and stomach. The Nodal signaling cascade in the left...
Organism or Cell Type:
Xenopus
Citation Extract:
Tingler M, Ott T, Tözser J, Kurz S, Getwan M, Tisler M, Schweickert A, Blum M. Symmetry breakage in the frog Xenopus: Role of Rab11 and the ventral-right blastomere. Genesis. 2014 Mar 2. doi: 10.1002/dvg.22766. [Epub ahead of print].

Quantitative analysis of orofacial development and median clefts in Xenopus laevis

Authors:
Kennedy AE, Dickinson AJ
Citation:
Anat Rec (Hoboken). 2014 May;297(5):834-55. doi: 10.1002/ar.22864. Epub 2014 Jan 17
Epub:
Not Epub
Abstract:
Xenopus has become a useful tool to study the molecular mechanisms underlying orofacial development. However, few quantitative...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kennedy AE, Dickinson AJ. Quantitative analysis of orofacial development and median clefts in Xenopus laevis. Anat Rec (Hoboken). 2014 May;297(5):834-55. doi: 10.1002/ar.22864. Epub 2014 Jan 17.

Endothelin-1 regulates H(+)-ATPase-dependent transepithelial H+ secretion in zebrafish

Authors:
Guh YJ, Tseng YC, Yang CY, Hwang PP
Citation:
Endocrinology. 2014 May;155(5):1728-37. doi: 10.1210/en.2013-1775. Epub 2014 Jan 1
Epub:
Not Epub
Abstract:
Endothelin-1 (EDN1) is an important regulator of H(+) secretion in the mammalian kidney. EDN1 enhances renal tubule H(+)-ATPase...
Organism or Cell Type:
zebrafish
Citation Extract:
Guh YJ, Tseng YC, Yang CY, Hwang PP. Endothelin-1 regulates H(+)-ATPase-dependent transepithelial H+ secretion in zebrafish. Endocrinology. 2014 May;155(5):1728-37. doi: 10.1210/en.2013-1775. Epub 2014 Jan 1.

Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo

Authors:
Ghiretti AE, Moore AR, Brenner RG, Chen LF, West AE, Lau NC, Van Hooser SD, Paradis S
Citation:
J Neurosci. 2014 Jan 8;34(2):392-407. doi: 10.1523/JNEUROSCI.1328-13.2014
Epub:
Not Epub
Abstract:
A key feature of the CNS is structural plasticity, the ability of neurons to alter their morphology and connectivity in...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ghiretti AE, Moore AR, Brenner RG, Chen LF, West AE, Lau NC, Van Hooser SD, Paradis S. Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo. J Neurosci. 2014 Jan 8;34(2):392-407. doi: 10.1523/JNEUROSCI.1328-13.2014.

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