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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson's' Disease (I5-2.003)

Authors:
Bandmann O, Keatinge M, DaCosta M, Mortiboys H, Flinn L
Citation:
Neurology. 2014;82(10):Supplement I5-2.003
Epub:
Not Epub
Abstract:
OBJECTIVE: To identify novel mechanisms which lead to dopaminergic cell death in early onset PD (EOPD) and determine whether...
Link:
http://www.neurology.org/content/82/10_Supplement/I5-2.003.short
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bandmann O, Keatinge M, DaCosta M, Mortiboys H, Flinn L. TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson's' Disease (I5-2.003). Neurology. 2014;82(10):Supplement I5-2.003.

Isradipine Rescues Alpha-synuclein Toxicity in a ZebrafishModel of Parkinson’s Disease by Upregulating Autophagy (1II-2.004)

Authors:
Stahl M, Prabhudesai S, Lulla A, Bronstein J
Citation:
Neurology. 2014. 82(10):Supplement 1II-2.004
Epub:
Not Epub
Abstract:
OBJECTIVE: To investigate the effect of isradipine, an L-type calcium channel blocker of the dihydropyridine class, on a...
Link:
http://www.neurology.org/content/82/10_Supplement/1II-2.004.short
Organism or Cell Type:
zebrafish
Citation Extract:
Stahl M, Prabhudesai S, Lulla A, Bronstein J. Isradipine Rescues Alpha-synuclein Toxicity in a ZebrafishModel of Parkinson’s Disease by Upregulating Autophagy (1II-2.004). Neurology. 2014. 82(10):Supplement 1II-2.004.

Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish

Authors:
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, Meng K, Xiong J-W
Citation:
J Cell Sci. 2014 Jun 15;127(Pt 12):2761-70. doi: 10.1242/jcs.145367. Epub 2014 Apr 11
Epub:
Yes
Abstract:
Protein tyrosine phosphatases (PTPs) such as SHP-1, SHP-2 and CD45 are involved in hematopoiesis, but the function of many PTPs...
Link:
http://jcs.biologists.org/content/early/2014/04/09/jcs.145367.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, Meng K, Xiong J-W. Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. J Cell Sci. 2014 Jun 15;127(Pt 12):2761-70. doi: 10.1242/jcs.145367. Epub 2014 Apr 11.

Antisense-Mediated Therapeutic Pseudoexon Skipping In Tmem165-Cdg

Authors:
Yuste-Checa P, Medrano C, Gámez A, Desviat L, Matthijs G, Ugarte M, Pérez-Cerdá C, Pérez B
Citation:
Clin Genet. 2014 Apr 10. doi: 10.1111/cge.12402. [Epub ahead of print]
Epub:
Yes
Abstract:
Deficiencies in glycosyltransferases, glycosidases or nucleotide-sugar transporters involved in protein glycosylation lead to...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/cge.12402/abstract
Organism or Cell Type:
cell culture: patient-derived fibroblasts
Citation Extract:
Yuste-Checa P, Medrano C, Gámez A, Desviat L, Matthijs G, Ugarte M, Pérez-Cerdá C, Pérez B. Antisense-Mediated Therapeutic Pseudoexon Skipping In Tmem165-Cdg. Clin Genet. 2014 Apr 10. doi: 10.1111/cge.12402. [Epub ahead of print].

Sp8 regulates inner ear development

Authors:
Chung HA, Medina-Ruiz S, Harland RM
Citation:
PNAS. 2014;[Epub ahead of print] doi:10.1073/pnas.1319301111
Epub:
Not Epub
Abstract:
Deficits in hearing or balance are common and result from both developmental and environmental causes. Model organisms have...
Link:
http://www.pnas.org/content/early/2014/04/09/1319301111.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Chung HA, Medina-Ruiz S, Harland RM. Sp8 regulates inner ear development. PNAS. 2014;[Epub ahead of print] doi:10.1073/pnas.1319301111 .

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

Authors:
Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND
Citation:
Development. 2013 Apr;140(7):1497-506. doi:10.1242/dev.084152. Epub 2013 Mar 5
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor C (Vegfc) is a secreted protein that guides lymphatic development in vertebrate embryos....
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596992/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND. A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development. 2013 Apr;140(7):1497-506. doi:10.1242/dev.084152. Epub 2013 Mar 5.

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut

Authors:
Dush MK, Nascone-Yoder NM
Citation:
Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5
Epub:
Not Epub
Abstract:
Tissue elongation is a fundamental morphogenetic process that generates the proper anatomical topology of the body plan and...
Link:
http://dev.biologists.org/content/140/7/1457.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dush MK, Nascone-Yoder NM. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5.

Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival

Authors:
Wu B, Piloto S, Zeng W, Hoverter NP, Schilling TF, Waterman ML
Citation:
EMBO Rep. 2013;14(4):347-55. doi:10.1038/embor.2013.19. Epub 2013 Mar 1
Epub:
Not Epub
Abstract:
T-cell factor/lymphoid enhancer factor (TCF/LEF) proteins regulate transcription by recruiting β-catenin and its associated co-...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615654/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu B, Piloto S, Zeng W, Hoverter NP, Schilling TF, Waterman ML. Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival. EMBO Rep. 2013;14(4):347-55. doi:10.1038/embor.2013.19. Epub 2013 Mar 1.

Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm

Authors:
Rydeen AB, Waxman JS
Citation:
Development. 2014;141:1638-1648. doi:10.1242/dev.105874
Epub:
Not Epub
Abstract:
Normal heart development requires appropriate levels of retinoic acid (RA) signaling. RA levels in embryos are dampened by...
Link:
http://dev.biologists.org/content/141/8/1638
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rydeen AB, Waxman JS. Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm. Development. 2014;141:1638-1648. doi:10.1242/dev.105874.

Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus

Authors:
Young JJ, Kjolby RAS, Kong NR, Monica SD, Harland RM
Citation:
Development. 2014;141:1683-1693. doi:10.1242/dev.099374
Epub:
Not Epub
Abstract:
Amphibian neural development occurs as a two-step process: (1) induction specifies a neural fate in undifferentiated ectoderm;...
Link:
http://dev.biologists.org/content/141/8/1683.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Young JJ, Kjolby RAS, Kong NR, Monica SD, Harland RM. Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus. Development. 2014;141:1683-1693. doi:10.1242/dev.099374.

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