You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Polarized Wnt Signaling Regulates Ectodermal Cell Fate in Xenopus

Authors:
Huang Y-L, Niehrs C
Citation:
Dev Cell. 2014;29(2):250-7. doi:10.1016/j.devcel.2014.03.015
Epub:
Not Epub
Abstract:
How cells convert polarity cues into cell fate specification is incompletely understood. Here, we show that Wnt/β-catenin and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y-L, Niehrs C. Polarized Wnt Signaling Regulates Ectodermal Cell Fate in Xenopus. Dev Cell. 2014;29(2):250-7. doi:10.1016/j.devcel.2014.03.015.

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation

Authors:
Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S
Citation:
Cells. 2014;3(2):363-385. doi:10.3390/cells3020363
Epub:
Not Epub
Abstract:
Rab GTPases are implicated in endosome-to-plasma membrane recycling, but how such membrane traffic regulators control vascular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S. Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation. Cells. 2014;3(2):363-385. doi:10.3390/cells3020363.

Specific NuRD components are required for fin regeneration in zebrafish

Authors:
Pfefferli C, Müller F, Jaźwińska A, Wicky C
Citation:
BMC Biology. 2014;(12):30 doi:10.1186/1741-7007-12-30
Epub:
Yes
Abstract:
Background: Epimorphic regeneration of a missing appendage in fish and urodele amphibians involves the creation of a blastema,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Pfefferli C, Müller F, Jaźwińska A, Wicky C. Specific NuRD components are required for fin regeneration in zebrafish. BMC Biology. 2014;(12):30 doi:10.1186/1741-7007-12-30.

Morpholino Antisense Oligonucleotides Targeting Intronic Repressor Element1 Improve Phenotype in SMA Mouse Models

Authors:
Osman EY, Miller MR, Robbins KL, Lombardi AM, Atkinson AK, Brehm AJ, Lorson CL
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu198
Epub:
Yes
Abstract:
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by the loss of Survival Motor Neuron-1 (SMN1). In all SMA...
Delivery Method:
ICV injection
Organism or Cell Type:
mouse SMNΔ7
Citation Extract:
Osman EY, Miller MR, Robbins KL, Lombardi AM, Atkinson AK, Brehm AJ, Lorson CL. Morpholino Antisense Oligonucleotides Targeting Intronic Repressor Element1 Improve Phenotype in SMA Mouse Models. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu198.

The Wnt/JNK signaling target gene alcam is required for embryonic kidney development

Authors:
Cizelsky W, Tata A, Kühl M, Kühl SJ
Citation:
Development. 2014 Apr 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Proper development of nephrons is essential for kidney function. β-Catenin-independent Wnt signaling through Fzd8, Inversin,...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cizelsky W, Tata A, Kühl M, Kühl SJ. The Wnt/JNK signaling target gene alcam is required for embryonic kidney development. Development. 2014 Apr 24. [Epub ahead of print].

Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo

Authors:
Araya C, Tawk M, Girdler GC, Costa M, Carmona-Fontaine C, Clarke JD
Citation:
Neural Dev. 2014 Apr 23;9(1):9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Morphogenesis of the zebrafish neural tube requires the coordinated movement of many cells in both time and space....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Araya C, Tawk M, Girdler GC, Costa M, Carmona-Fontaine C, Clarke JD. Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Dev. 2014 Apr 23;9(1):9. [Epub ahead of print].

Spectrum of Fates: a new approach to the study of the developing zebrafish retina

Authors:
Almeida AD, Boije H, Chow RW, He J, Tham J, Suzuki SC, Harris WA
Citation:
Development. 2014 May;141(9):1971-80. doi: 10.1242/dev.104760. Epub 2014 Apr 9
Epub:
Not Epub
Abstract:
The ability to image cells live and in situ as they proliferate and differentiate has proved to be an invaluable asset to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Almeida AD, Boije H, Chow RW, He J, Tham J, Suzuki SC, Harris WA. Spectrum of Fates: a new approach to the study of the developing zebrafish retina. Development. 2014 May;141(9):1971-80. doi: 10.1242/dev.104760. Epub 2014 Apr 9.

Formation and cultivation of medaka primordial germ cells

Authors:
Li Z, Li M, Hong N, Yi M, Hong Y
Citation:
Cell Tiss Res. 2014:{Epub ahead pf print} doi:10.1007/s00441-014-1867-z
Epub:
Yes
Abstract:
Primordial germ cell (PGC) formation is pivotal for fertility. Mammalian PGCs are epigenetically induced without the need for...
Delivery Method:
microinjection
Organism or Cell Type:
Medaka (Oryzias latipes)
Citation Extract:
Li Z, Li M, Hong N, Yi M, Hong Y. Formation and cultivation of medaka primordial germ cells. Cell Tiss Res. 2014:{Epub ahead pf print} doi:10.1007/s00441-014-1867-z.

Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy

Authors:
Gupta VA, Ravenscroft G, Shaheen R, Todd EJ, Swanson LC, Shiina M, Ogata K, Hsu C, Clarke NF, Darras BT, Farrar MA, Hashem A, Manton ND, Muntoni F, North KN, Sandaradura SA, Nishino I, Hayashi YK, Sewry CA, Thompson EM, Yau KS, Brownstein CA, Yu TW, Allcock RJ, Davis MR, Wallgren-Pettersson C, Matsumoto N, Alkuraya FS, Laing NG, Beggs AH
Citation:
Am J Hum Genet. 2013 Dec 5;93(6):1108-17. doi: 10.1016/j.ajhg.2013.10.020. Epub 2013 Nov 21
Epub:
Not Epub
Abstract:
Nemaline myopathy (NM) is a rare congenital muscle disorder primarily affecting skeletal muscles that results in neonatal death...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta VA, Ravenscroft G, Shaheen R, Todd EJ, Swanson LC, Shiina M, Ogata K, Hsu C, Clarke NF, Darras BT, Farrar MA, Hashem A, Manton ND, Muntoni F, North KN, Sandaradura SA, Nishino I, Hayashi YK, Sewry CA, Thompson EM, Yau KS, Brownstein CA, Yu TW, Allcock RJ, Davis MR, Wallgren-Pettersson C, Matsumoto N, Alkuraya FS, Laing NG, Beggs AH. Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy. Am J Hum Genet. 2013 Dec 5;93(6):1108-17. doi: 10.1016/j.ajhg.2013.10.020. Epub 2013 Nov 21.

CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration

Authors:
Schaffer AE, Eggens VRC, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu X-D, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG
Citation:
Cell. 2014;157(3):651-63. doi:10.1016/j.cell.2014.03.049
Epub:
Not Epub
Abstract:
Neurodegenerative diseases can occur so early as to affect neurodevelopment. From a cohort of more than 2,000 consanguineous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schaffer AE, Eggens VRC, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu X-D, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG. CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration. Cell. 2014;157(3):651-63. doi:10.1016/j.cell.2014.03.049.

Pages