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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress-Induced Inflammation

Authors:
Candel S, de Oliveira S, López-Muñoz A, García-Moreno D, Espín-Palazón R, Tyrkalska SD, Cayuela ML, Renshaw RA, Corbalán-Vélez R, Vidal-Abarca I, Tsai H-J, Meseguer J, Sepulcre MP, Mulero V
Citation:
PLoS Biol. 2014;12(5):e1001855. doi:10.1371/journal.pbio.1001855
Epub:
Not Epub
Abstract:
TNFα overexpression has been associated with several chronic inflammatory diseases, including psoriasis, lichen planus,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Candel S, de Oliveira S, López-Muñoz A, García-Moreno D, Espín-Palazón R, Tyrkalska SD, Cayuela ML, Renshaw RA, Corbalán-Vélez R, Vidal-Abarca I, Tsai H-J, Meseguer J, Sepulcre MP, Mulero V. Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress-Induced Inflammation. PLoS Biol. 2014;12(5):e1001855. doi:10.1371/journal.pbio.1001855.

Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration

Authors:
Tuttle AM, Hoffman TL, Schilling TF
Citation:
PLoS Biol. 2014;12(5):e1001852. doi:10.1371/journal.pbio.1001852
Epub:
Not Epub
Abstract:
Cell migration requires dynamic regulation of cell-cell signaling and cell adhesion. Both of these processes involve...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tuttle AM, Hoffman TL, Schilling TF. Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration. PLoS Biol. 2014;12(5):e1001852. doi:10.1371/journal.pbio.1001852.

Bucky ball organizes germ plasm assembly in zebrafish

Authors:
Bontems F, Stein A, Marlow F, Lyautey J, Gupta T, Mullins MC, Dosch R
Citation:
Curr Biol. 2009 Mar 10;19(5):414-22. doi: 10.1016/j.cub.2009.01.038. Epub 2009 Feb 26
Epub:
Not Epub
Abstract:
In many animals, gamete formation during embryogenesis is specified by maternal cytoplasmic determinants termed germ plasm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bontems F, Stein A, Marlow F, Lyautey J, Gupta T, Mullins MC, Dosch R. Bucky ball organizes germ plasm assembly in zebrafish. Curr Biol. 2009 Mar 10;19(5):414-22. doi: 10.1016/j.cub.2009.01.038. Epub 2009 Feb 26.

Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus

Authors:
Hett A, West S
Citation:
PLoS ONE. 2014;9(5):e96174. doi:10.1371/journal.pone.0096174
Epub:
Not Epub
Abstract:
Most human pre-mRNAs contain introns that are removed by splicing. Such a complex process needs strict control and regulation...
Delivery Method:
electroporation
Organism or Cell Type:
Cell culture:HeLa
Citation Extract:
Hett A, West S. Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus. PLoS ONE. 2014;9(5):e96174. doi:10.1371/journal.pone.0096174.

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

Authors:
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA
Citation:
Nucleic Acids Res. 2014 May 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Myotonic dystrophy type 1 (DM1) is a dominantly inherited neuromuscular disorder resulting from expression of RNA containing an...
Delivery Method:
injection (mouse), electroporation (C2C12 cells)
Organism or Cell Type:
mouse, cell culture:C2C12 myogenic cells
Citation Extract:
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA. Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects. Nucleic Acids Res. 2014 May 5. [Epub ahead of print].

Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish

Authors:
Chen LT, Liang WX, Chen S, Li RK, Tan JL, Xu PF, Luo LF, Wang L, Yu SH, Meng G, Li KK, Liu TX, Chen Z, Chen SJ
Citation:
Nat Commun. 2014 May 2;5:3811. doi: 10.1038/ncomms4811
Epub:
Not Epub
Abstract:
We previously reported a fusion protein NUP98-IQCG in an acute leukaemia, which functions as an aberrant regulator of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen LT, Liang WX, Chen S, Li RK, Tan JL, Xu PF, Luo LF, Wang L, Yu SH, Meng G, Li KK, Liu TX, Chen Z, Chen SJ. Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish. Nat Commun. 2014 May 2;5:3811. doi: 10.1038/ncomms4811.

The development of zebrafish tendon and ligament progenitors

Authors:
Chen JW, Galloway JL
Citation:
Development. 2014;141:2035-45. doi:10.1242/dev.104067
Epub:
Not Epub
Abstract:
Despite the importance of tendons and ligaments for transmitting movement and providing stability to the musculoskeletal system...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen JW, Galloway JL. The development of zebrafish tendon and ligament progenitors. Development. 2014;141:2035-45. doi:10.1242/dev.104067.

Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress

Authors:
Amir-Zilberstein L, Blechman J, Sztainberg Y, Norton WH, Reuveny A, Borodovsky N, Tahor M, Bonkowsky JL, Bally-Cuif L, Chen A, Levkowitz G
Citation:
Neuron. 2012 Jan 26;73(2):279-91. doi: 10.1016/j.neuron.2011.11.019
Epub:
Not Epub
Abstract:
Regulation of corticotropin-releasing hormone (CRH) activity is critical for the animal's adaptation to stressful...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amir-Zilberstein L, Blechman J, Sztainberg Y, Norton WH, Reuveny A, Borodovsky N, Tahor M, Bonkowsky JL, Bally-Cuif L, Chen A, Levkowitz G. Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress. Neuron. 2012 Jan 26;73(2):279-91. doi: 10.1016/j.neuron.2011.11.019.

Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis

Authors:
Barrios A, Poole RJ, Durbin L, Brennan C, Holder N, Wilson SW
Citation:
Curr Biol. 2003 Sep 16;13(18):1571-82
Epub:
Not Epub
Abstract:
BACKGROUND: During somitogenesis, segmental patterns of gene activity provide the instructions by which mesenchymal cells...
Delivery Method:
microinjection
Citation Extract:
Barrios A, Poole RJ, Durbin L, Brennan C, Holder N, Wilson SW. Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Curr Biol. 2003 Sep 16;13(18):1571-82.

Manipulation of BK channel expression is sufficient to alter auditory hair cell thresholds in larval zebrafish

Authors:
Rohmann KN, Tripp JA, Genova RM, Bass AH
Citation:
J Exp Biol. 2014;[Epub ahead of print] doi:10.1242/jeb.103093
Epub:
Yes
Abstract:
Non-mammalian vertebrates rely on electrical resonance for frequency tuning in auditory hair cells. A key component of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rohmann KN, Tripp JA, Genova RM, Bass AH. Manipulation of BK channel expression is sufficient to alter auditory hair cell thresholds in larval zebrafish. J Exp Biol. 2014;[Epub ahead of print] doi:10.1242/jeb.103093.

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