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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side

Authors:
Duboc V, Röttinger E, Lapraz F, Besnardeau L, Lepage T
Citation:
Dev Cell. 2005 Jul;9(1):147-58
Epub:
Not Epub
Abstract:
The asymmetric positioning of internal organs on the left or right side of the body is highly conserved in vertebrates and...
Delivery Method:
microinjection
Organism or Cell Type:
Sea urchin Paracentrotus lividus
Citation Extract:
Duboc V, Röttinger E, Lapraz F, Besnardeau L, Lepage T. Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side. Dev Cell. 2005 Jul;9(1):147-58.

Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity

Authors:
Ferguson DP, Dangott JJ, Timothy Lightfoot JT
Citation:
BioTechniques. 2014;56(5):251-6
Epub:
Not Epub
Abstract:
Vivo-morpholinos are a promising tool for gene silencing. These oligonucleotide analogs transiently silence genes by blocking...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice C57L/J
Citation Extract:
Ferguson DP, Dangott JJ, Timothy Lightfoot JT. Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity. BioTechniques. 2014;56(5):251-6.

Mutations in EMP2 Cause Childhood-Onset Nephrotic Syndrome

Authors:
Gee HY, Ashraf S, Wan X, Vega-Warner V, Esteve-Rudd J, Lovric S, Fang H, Hurd TW, Sadowski CE, Allen SJ, Otto EA, Korkmaz E, Washburn J, Levy S, Williams DS, Bakkaloglu SA, Zolotnitskaya A, Ozaltin F, Zhou W, Hildebrandt F
Citation:
Am J Hum Genet. 2014 Jun 5;94(6):884-90. doi: 10.1016/j.ajhg.2014.04.010. Epub 2014 May 8
Epub:
Yes
Abstract:
Nephrotic syndrome (NS) is a genetically heterogeneous group of diseases that are divided into steroid-sensitive NS (SSNS) and...
Organism or Cell Type:
zebrafish
Citation Extract:
Gee HY, Ashraf S, Wan X, Vega-Warner V, Esteve-Rudd J, Lovric S, Fang H, Hurd TW, Sadowski CE, Allen SJ, Otto EA, Korkmaz E, Washburn J, Levy S, Williams DS, Bakkaloglu SA, Zolotnitskaya A, Ozaltin F, Zhou W, Hildebrandt F. Mutations in EMP2 Cause Childhood-Onset Nephrotic Syndrome. Am J Hum Genet. 2014 Jun 5;94(6):884-90. doi: 10.1016/j.ajhg.2014.04.010. Epub 2014 May 8.

Activation-induced Tumor Necrosis Factor Receptor-associated Factor 3 (Traf3) Alternative Splicing Controls the Noncanonical Nuclear Factor κB Pathway and Chemokine Expression in Human T Cells

Authors:
Michel M, Wilhelmi I, Schultz A-S, Preussner M, Heyd F
Citation:
J Biol Chem. 2014;289:13651-60. doi:10.1074/jbc.M113.526269
Epub:
Not Epub
Abstract:
The noncanonical nuclear factor κB (ncNFκB) pathway regulates the expression of chemokines required for secondary lymphoid...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: jsl1 t-cells
Citation Extract:
Michel M, Wilhelmi I, Schultz A-S, Preussner M, Heyd F. Activation-induced Tumor Necrosis Factor Receptor-associated Factor 3 (Traf3) Alternative Splicing Controls the Noncanonical Nuclear Factor κB Pathway and Chemokine Expression in Human T Cells. J Biol Chem. 2014;289:13651-60. doi:10.1074/jbc.M113.526269 .

Delayed transition to new cell fates during cellular reprogramming

Authors:
Cheng X, Lyons DC, Socolar JE, McClay DR
Citation:
Dev Biol. 2014 Apr 26. pii: S0012-1606(14)00222-X. doi: 10.1016/j.ydbio.2014.04.015. [Epub ahead of print]
Epub:
Yes
Abstract:
In many embryos specification toward one cell fate can be diverted to a different cell fate through a reprogramming process....
Organism or Cell Type:
sea urchin
Citation Extract:
Cheng X, Lyons DC, Socolar JE, McClay DR. Delayed transition to new cell fates during cellular reprogramming. Dev Biol. 2014 Apr 26. pii: S0012-1606(14)00222-X. doi: 10.1016/j.ydbio.2014.04.015. [Epub ahead of print].

The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear

Authors:
Chang-Chien J, Yen Y-C, Chien K-H, Lia S-Y, Hsu T-C, Yang J-J
Citation:
Hearing Res. 2014;[Epub ahead of print] doi:10.1016/j.heares.2014.04.010
Epub:
Yes
Abstract:
The intercellular gap junction channels formed by connexins (CXs) are important for recycling potassium ions in the inner ear....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang-Chien J, Yen Y-C, Chien K-H, Lia S-Y, Hsu T-C, Yang J-J. The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear. Hearing Res. 2014;[Epub ahead of print] doi:10.1016/j.heares.2014.04.010.

DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG

Authors:
Klose RJ, Sarraf SA, Schmiedeberg L, McDermott SM, Stancheva I, Bird AP
Citation:
Mol Cell. 2005 Sep 2;19(5):667-78
Epub:
Not Epub
Abstract:
DNA methylation is interpreted by a family of methyl-CpG binding domain (MBD) proteins that repress transcription through...
Organism or Cell Type:
cell culture: MRC-5 cells
Citation Extract:
Klose RJ, Sarraf SA, Schmiedeberg L, McDermott SM, Stancheva I, Bird AP. DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. Mol Cell. 2005 Sep 2;19(5):667-78.

Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis

Authors:
Blanco-Sánchez B, Clément A, Fierro J Jr, Washbourne P, Westerfield M
Citation:
Dis Model Mech. 2014 May;7(5):547-59. doi: 10.1242/dmm.014068. Epub 2014 Mar 13
Epub:
Not Epub
Abstract:
Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blanco-Sánchez B, Clément A, Fierro J Jr, Washbourne P, Westerfield M. Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis. Dis Model Mech. 2014 May;7(5):547-59. doi: 10.1242/dmm.014068. Epub 2014 Mar 13.

A noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defects

Authors:
Favaro FP, Alvizi L, Zechi-Ceide RM, Bertola D, Felix TM, de Souza J, Raskin S, Twigg SR, Weiner AM, Armas P, Margarit E, Calcaterra NB, Andersen GR, McGowan SJ, Wilkie AO, Richieri-Costa A, de Almeida ML, Passos-Bueno MR
Citation:
Am J Hum Genet. 2014 Jan 2;94(1):120-8. doi: 10.1016/j.ajhg.2013.11.020. Epub 2013 Dec 19
Epub:
Not Epub
Abstract:
Richieri-Costa-Pereira syndrome is an autosomal-recessive acrofacial dysostosis characterized by mandibular median cleft...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Favaro FP, Alvizi L, Zechi-Ceide RM, Bertola D, Felix TM, de Souza J, Raskin S, Twigg SR, Weiner AM, Armas P, Margarit E, Calcaterra NB, Andersen GR, McGowan SJ, Wilkie AO, Richieri-Costa A, de Almeida ML, Passos-Bueno MR. A noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defects. Am J Hum Genet. 2014 Jan 2;94(1):120-8. doi: 10.1016/j.ajhg.2013.11.020. Epub 2013 Dec 19.

Dynamic Expression of Chymotrypsin-Like Elastase 1 Over the Course of Murine Lung Development

Authors:
Liu S, Young SM, Varisco BM
Citation:
Am J Physiol Lung Cell Mol Physiol. 2014 May 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Postnatal lung development requires coordination of three processes-surface area expansion, microvascular growth, and matrix...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice C57BL/6J
Citation Extract:
Liu S, Young SM, Varisco BM. Dynamic Expression of Chymotrypsin-Like Elastase 1 Over the Course of Murine Lung Development. Am J Physiol Lung Cell Mol Physiol. 2014 May 2. [Epub ahead of print].

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