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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions
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Citation:
Dev Biol. 2014 Jul 8. pii: S0012-1606(14)00322-4. doi: 10.1016/j.ydbio.2014.06.026. [Epub ahead of print] Epub:
Not Epub Abstract:
The Wilms tumor suppressor gene Wt1 encodes a zinc finger transcription factor that is essential for development of multiple... Organism or Cell Type:
zebrafish Citation Extract: Schnerwitzki D, Perner B, Hoppe B, Pietsch S, Mehringer R, Hänel F, Englert C. Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions. Dev Biol. 2014 Jul 8. pii: S0012-1606(14)00322-4. doi: 10.1016/j.ydbio.2014.06.026. [Epub ahead of print]. |
Fam40b is required for lineage commitment of murine embryonic stem cells
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Citation:
Cell Death Dis. 2014 Jul 10;5:e1320. doi: 10.1038/cddis.2014.273 Epub:
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FAM40B (STRIP2) is a member of the striatin-interacting phosphatase and kinase (STRIPAK) complex that is involved in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wagh V, Doss MX, Sabour D, Niemann R, Meganathan K, Jagtap S, Gaspar JA, Ardestani MA, Papadopoulos S, Gajewski M, Winkler J, Hescheler J, Sachinidis A. Fam40b is required for lineage commitment of murine embryonic stem cells. Cell Death Dis. 2014 Jul 10;5:e1320. doi: 10.1038/cddis.2014.273. |
Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development
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Citation:
Molec Cell. 2014;[Epub ahead of print] doi:10.1016/j.molcel.2014.06.006 Epub:
Yes Abstract:
Histone H3K4 demethylase LSD1 plays an important role in stem cell biology, especially in the maintenance of the silencing of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Han X, Gui B, Xiong C, Zhao L, Liang J, Sun L, Yang X, Yu W, Si W, Yan R, Yi X, Zhang D, Li W, Li L, Yang J, Wang Y, Sun YE, Zhang D, Meng A, Shang Y. Destabilizing LSD1 by Jade-2 Promotes Neurogenesis: An Antibraking System in Neural Development. Molec Cell. 2014;[Epub ahead of print] doi:10.1016/j.molcel.2014.06.006. |
Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification
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Citation:
Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322 Epub:
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Head specification by the head-selector gene, orthodenticle (otx), is highly conserved among bilaterian lineages. However, the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification. Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322. |
Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy
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Citation:
Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012 Epub:
Not Epub Abstract:
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roosing S, Lamers IJC, de Vrieze E, van den Born LI, Lambertus S, Arts HH, POC1B Study Group, Peters TA, Hoyng CB, Kremer H, Hetterschijt L, Letteboer SJF, van Wijk E, Roepman R, den Hollander AI, Cremers FPM. Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy. Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012. |
A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis
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Citation:
PLoS Genet. 2014;10(7):e1004450. doi:10.1371/journal.pgen.1004450 Epub:
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The formation of mature cells by blood stem cells is very well understood at the cellular level and we know many of the key... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bielczyk-Maczyńska E, Serbanovic-Canic J, Ferreira L, Soranzo N, Stemple DL, Ouwehand WH, Cvejic A. A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis. PLoS Genet. 2014;10(7):e1004450. doi:10.1371/journal.pgen.1004450. |
Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis
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Citation:
PLoS Genet. 2014;10(7):e1004491. doi:10.1371/journal.pgen.1004491 Epub:
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Ocular coloboma is a sight-threatening malformation caused by failure of the choroid fissure to close during morphogenesis of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pillai-Kastoori L, Wen W, Wilson SG, Strachan E, Lo-Castro A, Fichera M, Musumeci SA, Lehmann OJ, Morris AC. Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis. PLoS Genet. 2014;10(7):e1004491. doi:10.1371/journal.pgen.1004491. |
Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish
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Citation:
Blood. 2014 Sep 4;124(10):1578-85. doi: 10.1182/blood-2013-11-541391. Epub 2014 Jul 8 Epub:
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Nuclear receptor co-repressors (Ncor) are important for developmental and homeostatic processes in vertebrates, which exert... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wei Y, Ma D, Gao Y, Zhang C, Wang L, Liu F. Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish. Blood. 2014 Sep 4;124(10):1578-85. doi: 10.1182/blood-2013-11-541391. Epub 2014 Jul 8. |
WNK1/HSN2 isoform and the regulation of KCC2 activity
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Citation:
Rare Dis. 2013 Sep 19;1:e26537. doi: 10.4161/rdis.26537. eCollection 2013 Epub:
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Hereditary sensory and autonomic neuropathy type 2 is a rare autosomal recessive pathology presenting with early onset... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bercier V. WNK1/HSN2 isoform and the regulation of KCC2 activity. Rare Dis. 2013 Sep 19;1:e26537. doi: 10.4161/rdis.26537. eCollection 2013. |
aldh7a1 Regulates Eye and Limb Development in Zebrafish
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Citation:
PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014 Epub:
Not Epub Abstract:
Uveal coloboma is a potentially blinding congenital ocular malformation caused by failure of the optic fissure to close during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP. aldh7a1 Regulates Eye and Limb Development in Zebrafish. PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014. |