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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Gli1 Activation and Protection Against Hepatic Encephalopathy is Suppressed by Circulating Transforming Growth Factor β1 in Mice

Authors:
McMillin M, Galindo C, Pae HY, Frampton G, Di Patre PL, Quinn M, Whittington E, DeMorrow S
Citation:
J Hepatol. 2014;[Epub ahead of print] doi:10.1016/j.jhep.2014.07.015
Epub:
Not Epub
Abstract:
Background & Aims: Hepatic encephalopathy (HE) is a neurologic disorder that develops during liver failure. Few studies...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
McMillin M, Galindo C, Pae HY, Frampton G, Di Patre PL, Quinn M, Whittington E, DeMorrow S. Gli1 Activation and Protection Against Hepatic Encephalopathy is Suppressed by Circulating Transforming Growth Factor β1 in Mice. J Hepatol. 2014;[Epub ahead of print] doi:10.1016/j.jhep.2014.07.015.

WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors

Authors:
Motamedi FJ, Badro DA, Clarkson M, Rita Lecca M, Bradford ST, Buske FA, Saar K, Hübner N, Brändli AW, Schedl A
Citation:
Nat Commun. 2014 Jul 17;5:4444. doi: 10.1038/ncomms5444
Epub:
Not Epub
Abstract:
Kidney organogenesis requires the tight control of proliferation, differentiation and apoptosis of renal progenitor cells. How...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
organ culture: mouse kidney
Citation Extract:
Motamedi FJ, Badro DA, Clarkson M, Rita Lecca M, Bradford ST, Buske FA, Saar K, Hübner N, Brändli AW, Schedl A. WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors. Nat Commun. 2014 Jul 17;5:4444. doi: 10.1038/ncomms5444.

APC Is an RNA-Binding Protein, and Its Interactome Provides a Link to Neural Development and Microtubule Assembly

Authors:
Preitner N, Quan J, Nowakowski DW, Hancock ML, Shi J, Tcherkezian J, Young-Pearse TL, Flanagan JG
Citation:
Cell. 2014 Jul 17;158(2):368-82. doi: 10.1016/j.cell.2014.05.042
Epub:
Not Epub
Abstract:
Adenomatous polyposis coli (APC) is a microtubule plus-end scaffolding protein important in biology and disease. APC is...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Rat brain in utero
Citation Extract:
Preitner N, Quan J, Nowakowski DW, Hancock ML, Shi J, Tcherkezian J, Young-Pearse TL, Flanagan JG. APC Is an RNA-Binding Protein, and Its Interactome Provides a Link to Neural Development and Microtubule Assembly. Cell. 2014 Jul 17;158(2):368-82. doi: 10.1016/j.cell.2014.05.042.

The Extreme Anterior Domain Is an Essential Craniofacial Organizer Acting through Kinin-Kallikrein Signaling

Authors:
Jacox L, Sindelka R, Chen J, Rothman A, Dickinson A, Sive H
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.06.026
Epub:
Yes
Abstract:
The extreme anterior domain (EAD) is a conserved embryonic region that includes the presumptive mouth. We show that the Kinin-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Jacox L, Sindelka R, Chen J, Rothman A, Dickinson A, Sive H. The Extreme Anterior Domain Is an Essential Craniofacial Organizer Acting through Kinin-Kallikrein Signaling. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.06.026.

IGF binding protein 3 exerts its ligand-independent action by antagonizing BMP in zebrafish embryos

Authors:
Zhong Y, Lu L, Zhou J, Li Y, Liu Y, Clemmons DR, Duan C
Citation:
J Cell Sci. 2011 Jun 1;124(Pt 11):1925-35. doi: 10.1242/jcs.082644. Epub 2011 May 10
Epub:
Not Epub
Abstract:
IGFBP3 is a multi-functional protein that has IGF-dependent and IGF-independent actions in cultured cells. Here we show that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Y, Lu L, Zhou J, Li Y, Liu Y, Clemmons DR, Duan C. IGF binding protein 3 exerts its ligand-independent action by antagonizing BMP in zebrafish embryos. J Cell Sci. 2011 Jun 1;124(Pt 11):1925-35. doi: 10.1242/jcs.082644. Epub 2011 May 10.

The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish

Authors:
Paridaen JT, Janson E, Utami KH, Pereboom TC, Essers PB, van Rooijen C, Zivkovic D, MacInnes AW
Citation:
Dev Biol. 2011 Jul 15;355(2):286-301. doi: 10.1016/j.ydbio.2011.04.028. Epub 2011 Apr 30
Epub:
Not Epub
Abstract:
Nucleostemin (NS), a member of a family of nucleolar GTP-binding proteins, is highly expressed in proliferating cells such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paridaen JT, Janson E, Utami KH, Pereboom TC, Essers PB, van Rooijen C, Zivkovic D, MacInnes AW. The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish. Dev Biol. 2011 Jul 15;355(2):286-301. doi: 10.1016/j.ydbio.2011.04.028. Epub 2011 Apr 30.

The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos

Authors:
Hashimoto H, Enomoto T, Kumano G, Nishida H
Citation:
Development. 2011 Jun;138(12):2591-600. doi: 10.1242/dev.053082. Erratum in: Development. 2011 Jun;138(12). doi: 10.1242/dev.070383. Enomoto, Atsushi [corrected to Enomoto, Takashi]. Development. 2011 Jul;138(14):3091
Epub:
Not Epub
Abstract:
In embryos of the ascidian Halocynthia roretzi, the competence of isolated presumptive notochord blastomeres to respond to...
Delivery Method:
microinjection
Organism or Cell Type:
Halocynthia roretzi
Citation Extract:
Hashimoto H, Enomoto T, Kumano G, Nishida H. The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos. Development. 2011 Jun;138(12):2591-600. doi: 10.1242/dev.053082. Erratum in: Development. 2011 Jun;138(12). doi: 10.1242/dev.070383. Enomoto, Atsushi [corrected to Enomoto, Takashi]. Development. 2011 Jul;138(14):3091.

Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

Authors:
Kumai Y, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1517-28. doi: 10.1152/ajpregu.00282.2011. Epub 2011 Aug 10
Epub:
Not Epub
Abstract:
The involvement of a Na+/H+ exchanger (NHE) in mediating Na+ uptake by freshwater fish is currently debated. Although supported...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Perry SF. Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1517-28. doi: 10.1152/ajpregu.00282.2011. Epub 2011 Aug 10.

The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis

Authors:
Rodríguez P, Higueras MA, González-Rajal A, Alfranca A, Fierro-Fernández M, García-Fernández RA, Ruiz-Hidalgo MJ, Monsalve M, Rodríguez-Pascual F, Redondo JM, de la Pompa JL, Laborda J, Lamas S
Citation:
Cardiovasc Res. 2012 Feb 1;93(2):232-41. doi: 10.1093/cvr/cvr296. Epub 2011 Nov 8
Epub:
Not Epub
Abstract:
AIMS: The epidermal growth factor-like protein Delta-like 1 (DLK1) regulates multiple differentiation processes. It resembles...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez P, Higueras MA, González-Rajal A, Alfranca A, Fierro-Fernández M, García-Fernández RA, Ruiz-Hidalgo MJ, Monsalve M, Rodríguez-Pascual F, Redondo JM, de la Pompa JL, Laborda J, Lamas S. The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovasc Res. 2012 Feb 1;93(2):232-41. doi: 10.1093/cvr/cvr296. Epub 2011 Nov 8.

A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization

Authors:
Pereboom TC, van Weele LJ, Bondt A, MacInnes AW
Citation:
Blood. 2011 Nov 17;118(20):5458-65. doi: 10.1182/blood-2011-04-351460. Epub 2011 Sep 14
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is a bone marrow failure disorder characterized by shortened telomeres, defective stem cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pereboom TC, van Weele LJ, Bondt A, MacInnes AW. A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization. Blood. 2011 Nov 17;118(20):5458-65. doi: 10.1182/blood-2011-04-351460. Epub 2011 Sep 14.

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