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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia

Authors:
Bhatia S, Bengani H, Fish M, Brown A, Divizia MT, de Marco R, Damante G, Grainger R, van Heyningen V, Kleinjan DA
Citation:
Am J Hum Genet. 2013 Dec 5;93(6):1126-34. doi: 10.1016/j.ajhg.2013.10.028. Epub 2013 Nov 27. Review
Epub:
Not Epub
Abstract:
The strictly regulated expression of most pleiotropic developmental control genes is critically dependent on the activity of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhatia S, Bengani H, Fish M, Brown A, Divizia MT, de Marco R, Damante G, Grainger R, van Heyningen V, Kleinjan DA. Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia. Am J Hum Genet. 2013 Dec 5;93(6):1126-34. doi: 10.1016/j.ajhg.2013.10.028. Epub 2013 Nov 27. Review.

Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment

Authors:
Ljubimova JY, Portilla-Arias J, Patil R, Ding H, Inoue S, Markman JL, Rekechenetskiy A, Konda B, Gangalum PR, Chesnokova A, Ljubimov AV, Black KL, Holler E
Citation:
J Drug Target. 2013 Dec;21(10):956-67. doi: 10.3109/1061186X.2013.837470. Epub 2013 Sep 16
Epub:
Not Epub
Abstract:
Engineered nanoparticles are widely used for delivery of drugs but frequently lack proof of safety for cancer patient's...
Delivery Method:
injection
Organism or Cell Type:
mice
Citation Extract:
Ljubimova JY, Portilla-Arias J, Patil R, Ding H, Inoue S, Markman JL, Rekechenetskiy A, Konda B, Gangalum PR, Chesnokova A, Ljubimov AV, Black KL, Holler E. Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment. J Drug Target. 2013 Dec;21(10):956-67. doi: 10.3109/1061186X.2013.837470. Epub 2013 Sep 16.

Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate

Authors:
Tereshina MB, Ermakova GV, Ivanova AS, Zaraisky AG
Citation:
Biol Open. 2014 Mar 15;3(3):192-203. doi: 10.1242/bio.20147401
Epub:
Not Epub
Abstract:
We previously found that the small GTPase Ras-dva1 is essential for the telencephalic development in Xenopus laevis because Ras...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tereshina MB, Ermakova GV, Ivanova AS, Zaraisky AG. Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate. Biol Open. 2014 Mar 15;3(3):192-203. doi: 10.1242/bio.20147401.

Zebrafish churchill regulates developmental gene expression and cell migration

Authors:
Taibi A, Mandavawala KP, Noel J, Okoye EV, Milano CR, Martin BL, Sirotkin HI
Citation:
Dev Dyn. 2013 Jun;242(6):614-21. doi: 10.1002/dvdy.23958. Epub 2013 Mar 29
Epub:
Not Epub
Abstract:
BACKGROUND: Regulation of developmental signaling pathways is essential for embryogenesis. The small putative zinc finger...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taibi A, Mandavawala KP, Noel J, Okoye EV, Milano CR, Martin BL, Sirotkin HI. Zebrafish churchill regulates developmental gene expression and cell migration. Dev Dyn. 2013 Jun;242(6):614-21. doi: 10.1002/dvdy.23958. Epub 2013 Mar 29.

Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development

Authors:
José-Edwards DS, Oda-Ishii I, Nibu Y, Di Gregorio A
Citation:
Development. 2013 Jun;140(11):2422-33. doi: 10.1242/dev.094227
Epub:
Not Epub
Abstract:
T-box genes are potent regulators of mesoderm development in many metazoans. In chordate embryos, the T-box transcription...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
José-Edwards DS, Oda-Ishii I, Nibu Y, Di Gregorio A. Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development. Development. 2013 Jun;140(11):2422-33. doi: 10.1242/dev.094227.

Tcf21 regulates the specification and maturation of proepicardial cells

Authors:
Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL
Citation:
Development. 2013 Jun;140(11):2409-21. doi: 10.1242/dev.093385. Epub 2013 May 1
Epub:
Not Epub
Abstract:
The epicardium is a mesothelial cell layer essential for vertebrate heart development and pertinent for cardiac repair post-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL. Tcf21 regulates the specification and maturation of proepicardial cells. Development. 2013 Jun;140(11):2409-21. doi: 10.1242/dev.093385. Epub 2013 May 1.

Xenopus Dead end mRNA is a localized maternal determinant that serves a conserved function in germ cell development

Authors:
Horvay K, Claussen M, Katzer M, Landgrebe J, Pieler T
Citation:
Dev Biol. 2006 Mar 1;291(1):1-11. Epub 2006 Jan 30
Epub:
Not Epub
Abstract:
Germ plasm formation is considered to define the first step in germ cell development. Xenopus Dead end represents a germ plasm...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Horvay K, Claussen M, Katzer M, Landgrebe J, Pieler T. Xenopus Dead end mRNA is a localized maternal determinant that serves a conserved function in germ cell development. Dev Biol. 2006 Mar 1;291(1):1-11. Epub 2006 Jan 30.

Strategies to discover the structural components of cyst and oocyst walls

Authors:
Samuelson J, Bushkin GG, Chatterjee A, Robbins PW
Citation:
Eukaryot Cell. 2013 Dec;12(12):1578-87. doi: 10.1128/EC.00213-13. Epub 2013 Oct 4. Review
Epub:
Not Epub
Abstract:
Cysts of Giardia lamblia and Entamoeba histolytica and oocysts of Toxoplasma gondii and Cryptosporidium parvum are the...
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Samuelson J, Bushkin GG, Chatterjee A, Robbins PW. Strategies to discover the structural components of cyst and oocyst walls. Eukaryot Cell. 2013 Dec;12(12):1578-87. doi: 10.1128/EC.00213-13. Epub 2013 Oct 4. Review.

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

Authors:
Simpson CL, Lemmens R, Miskiewicz K, Broom WJ, Hansen VK, van Vught PW, Landers JE, Sapp P, Van Den Bosch L, Knight J, Neale BM, Turner MR, Veldink JH, Ophoff RA, Tripathi VB, Beleza A, Shah MN, Proitsi P, Van Hoecke A, Carmeliet P, Horvitz HR, Leigh PN, Shaw CE, van den Berg LH, Sham PC, Powell JF, Verstreken P, Brown RH Jr, Robberecht W, Al-Chalabi A
Citation:
Hum Mol Genet. 2009 Feb 1;18(3):472-81. doi: 10.1093/hmg/ddn375. Epub 2008 Nov 7
Epub:
Not Epub
Abstract:
Amyotrophic lateral sclerosis (ALS) is a spontaneous, relentlessly progressive motor neuron disease, usually resulting in death...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Simpson CL, Lemmens R, Miskiewicz K, Broom WJ, Hansen VK, van Vught PW, Landers JE, Sapp P, Van Den Bosch L, Knight J, Neale BM, Turner MR, Veldink JH, Ophoff RA, Tripathi VB, Beleza A, Shah MN, Proitsi P, Van Hoecke A, Carmeliet P, Horvitz HR, Leigh PN, Shaw CE, van den Berg LH, Sham PC, Powell JF, Verstreken P, Brown RH Jr, Robberecht W, Al-Chalabi A. Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration. Hum Mol Genet. 2009 Feb 1;18(3):472-81. doi: 10.1093/hmg/ddn375. Epub 2008 Nov 7.

In vivo microinjection of antisense morpholino oligos to predict the teratogenic potential of new drugs: An initial validation work on VEGF

Authors:
Manera D, Longo M, Zanoncelli S, Meroni P, Gunnarsson K
Citation:
Toxicol Lett (shannon). 144(supp.1):S108-S109 doi:10.1016/S0378-4274(03)90398-5
Epub:
Not Epub
Citation Extract:
Manera D, Longo M, Zanoncelli S, Meroni P, Gunnarsson K. In vivo microinjection of antisense morpholino oligos to predict the teratogenic potential of new drugs: An initial validation work on VEGF. Toxicol Lett (shannon). 144(supp.1):S108-S109 doi:10.1016/S0378-4274(03)90398-5.

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