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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome
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Citation:
Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: To elucidate the genetic cause of a rare recessive ataxia presented by 2 siblings from a consanguineous Turkish... Organism or Cell Type:
zebrafish Citation Extract: Burns R, Majczenko K, Xu J, Peng W, Yapici Z, Dowling JJ, Li JZ, Burmeister M. Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome. Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print]. |
A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus
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Citation:
Science. 2014;346(6209):641-6. doi:10.1126/science.1258705 Epub:
Not Epub Abstract:
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus. Science. 2014;346(6209):641-6. doi:10.1126/science.1258705. |
A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies
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Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555 Epub:
Yes Abstract:
Jeune asphyxiating thoracic dystrophy (JATD) is a skeletal dysplasia characterized by a small thoracic cage and a range of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shaheen R, Schmidts M, Faqeih E, Hashem A, Lausch E, Holder I, Superti-Furga A, UK10 K consortium, Mitchison HM, Almoisheer A, Alamro R, Alshiddi T, Alzahrani F, Beales PL, Alkuraya FS. A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555 . |
Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain
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Citation:
PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014 Epub:
Not Epub Abstract:
Fibroblast growth factor (Fgf) signaling plays crucial roles in various developmental processes including those in the brain.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N. Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain. PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014. |
Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice
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Citation:
Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014 Epub:
Not Epub Abstract:
Although an increasing number of antibody conjugates are being used in the clinic, there remain many unmet needs in antibody... Delivery Method:
pretargeting Organism or Cell Type:
mice Citation Extract: Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G. Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice. Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014. |
Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish
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Citation:
J Virol. 2015 Jan;89(1):763-75. doi: 10.1128/JVI.01955-14. Epub 2014 Oct 29. PMID: 25355883; PMCID: PMC4301147 Epub:
Yes Abstract:
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus, Iridoviridae family,... Delivery Method:
injection Organism or Cell Type:
zebrafish Citation Extract: Yuan JM, He BL, Yang LY, Guo CJ, Weng SP, Li SC, He JG. Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish. J Virol. 2015 Jan;89(1):763-75. doi: 10.1128/JVI.01955-14. Epub 2014 Oct 29. PMID: 25355883; PMCID: PMC4301147. |
Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease
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Citation:
Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57 Epub:
Not Epub Abstract:
Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA; EC 3.2.1.20) and the... Delivery Method:
injection & electroporation or peptide-linked Organism or Cell Type:
mice Citation Extract: Clayton NP, Nelson CA, Weeden T, Taylor KM, Moreland RJ, Scheule RK, Phillips L, Leger AJ, Cheng SH, Wentworth BM. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease. Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57. |
FIH-1, a Novel Interactor of Mindbomb, Functions as an Essential Anti-Angiogenic Factor during Zebrafish Vascular Development
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Citation:
PLoS ONE. 2014;9(10):e109517. doi:10.1371/journal.pone.0109517 Epub:
Not Epub Abstract:
Objective: It has been shown that Mindbomb (Mib), an E3 Ubiquitin ligase, is an essential modulator of Notch signaling during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: So J-H, Kim J-D, Yoo K-W, Kim H-T, Jung S-H, Choi J-H, Lee M-S, Jin S-W. FIH-1, a Novel Interactor of Mindbomb, Functions as an Essential Anti-Angiogenic Factor during Zebrafish Vascular Development. PLoS ONE. 2014;9(10):e109517. doi:10.1371/journal.pone.0109517. |
FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis
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Citation:
Nat Commun. 2014 Oct 24;5:5240. doi: 10.1038/ncomms6240 Epub:
Not Epub Abstract:
Spindle orientation is critical for proper morphogenesis of organs and tissues as well as for the maintenance of tissue... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Petridou NI, Skourides PA. FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. Nat Commun. 2014 Oct 24;5:5240. doi: 10.1038/ncomms6240. |
Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy
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Citation:
Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3122. [Epub ahead of print] Epub:
Yes Abstract:
Centrioles are essential for ciliogenesis. However, mutations in centriole biogenesis genes have been reported in primary... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Daire VC, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3122. [Epub ahead of print]. |