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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates

Authors:
Bessa J, Luengo M, Rivero-Gil S, Ariza-Cosano A, Maia AH, Ruiz-Ruano FJ, Caballero P, Naranjo S, Carvajal JJ, Gómez-Skarmeta JL
Citation:
Genome Res. 2014 Mar;24(3):487-95. doi: 10.1101/gr.165654.113. Epub 2013 Nov 25
Epub:
Not Epub
Abstract:
In multicellular organisms, cis-regulation controls gene expression in space and time. Despite the essential implication of cis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bessa J, Luengo M, Rivero-Gil S, Ariza-Cosano A, Maia AH, Ruiz-Ruano FJ, Caballero P, Naranjo S, Carvajal JJ, Gómez-Skarmeta JL. A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates. Genome Res. 2014 Mar;24(3):487-95. doi: 10.1101/gr.165654.113. Epub 2013 Nov 25.

Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata

Authors:
Lee J, Lee BK, Gross JM
Citation:
Hum Mol Genet. 2013 Sep 1;22(17):3568-82. doi: 10.1093/hmg/ddt211. Epub 2013 May 12
Epub:
Not Epub
Abstract:
Mutations in BCOR (Bcl6 corepressor) are found in patients with oculo-facio-cardio-dental (OFCD) syndrome, a congenital...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Lee BK, Gross JM. Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata. Hum Mol Genet. 2013 Sep 1;22(17):3568-82. doi: 10.1093/hmg/ddt211. Epub 2013 May 12.

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites

Authors:
Kim Y-J, Bahn M, Kim YH, Shin J-Y, Cheong S-W, Ju B-G, Kim W-S, Yeo C-Y
Citation:
Dev Biol. 2014 Nov 4. pii: S0012-1606(14)00560-0. doi: 10.1016/j.ydbio.2014.10.019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Members of the fibroblast growth factor (FGF) family play important roles during various developmental processes including eye...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim Y-J, Bahn M, Kim YH, Shin J-Y, Cheong S-W, Ju B-G, Kim W-S, Yeo C-Y. Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites. Dev Biol. 2014 Nov 4. pii: S0012-1606(14)00560-0. doi: 10.1016/j.ydbio.2014.10.019. [Epub ahead of print].

The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis

Authors:
Kim M, Kim M, Lee MS, Kim CH, Lim DS
Citation:
Nat Commun. 2014 Nov 4;5:5370. doi: 10.1038/ncomms6370
Epub:
Not Epub
Abstract:
Primary cilia are microtubule-based organelles that protrude from polarized epithelial cells. Although many structural and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim M, Kim M, Lee MS, Kim CH, Lim DS. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014 Nov 4;5:5370. doi: 10.1038/ncomms6370.

Itch Is Required for Lateral Line Development in Zebrafish

Authors:
Angers A, Drapeau P
Citation:
PLoS One. 2014 Nov 4;9(11):e111799. doi: 10.1371/journal.pone.0111799. eCollection 2014
Epub:
Not Epub
Abstract:
The zebrafish posterior lateral line is formed during early development by the deposition of neuromasts from a migrating...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Angers A, Drapeau P. Itch Is Required for Lateral Line Development in Zebrafish. PLoS One. 2014 Nov 4;9(11):e111799. doi: 10.1371/journal.pone.0111799. eCollection 2014.

The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes

Authors:
Dupré A, Buffin E, Roustan C, Nairn AC, Jessus C, Haccard O
Citation:
J Cell Sci. 2013 Sep 1;126(Pt 17):3916-26. doi: 10.1242/jcs.126599. Epub 2013 Jun 18
Epub:
Not Epub
Abstract:
Entry into mitosis or meiosis relies on the coordinated action of kinases and phosphatases that ultimately leads to the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dupré A, Buffin E, Roustan C, Nairn AC, Jessus C, Haccard O. The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes. J Cell Sci. 2013 Sep 1;126(Pt 17):3916-26. doi: 10.1242/jcs.126599. Epub 2013 Jun 18.

TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model

Authors:
Ge L, Zhang RP, Wan F, Guo DY, Wang P, Xiang LX, Shao JZ
Citation:
Mol Cell Biol. 2014 Mar;34(6):989-1002. doi: 10.1128/MCB.01061-13. Epub 2014 Jan 6
Epub:
Not Epub
Abstract:
Although epigenetic modulation is critical for a variety of cellular activities, its role in erythropoiesis remains poorly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ge L, Zhang RP, Wan F, Guo DY, Wang P, Xiang LX, Shao JZ. TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model. Mol Cell Biol. 2014 Mar;34(6):989-1002. doi: 10.1128/MCB.01061-13. Epub 2014 Jan 6.

Caveolin isoform switching as a molecular, structural, and metabolic regulator of microglia

Authors:
Niesman IR, Zemke N, Fridolfsson HN, Haushalter KJ, Levy K, Grove A, Schnoor R, Finley JC, Patel PM, Roth DM, Head BP, Patel HH
Citation:
Mol Cell Neurosci. 2013 Sep;56:283-97. doi: 10.1016/j.mcn.2013.07.002. Epub 2013 Jul 10
Epub:
Not Epub
Abstract:
Microglia are ramified cells that serve as central nervous system (CNS) guardians, capable of proliferation, migration, and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary mouse derived microglia
Citation Extract:
Niesman IR, Zemke N, Fridolfsson HN, Haushalter KJ, Levy K, Grove A, Schnoor R, Finley JC, Patel PM, Roth DM, Head BP, Patel HH. Caveolin isoform switching as a molecular, structural, and metabolic regulator of microglia. Mol Cell Neurosci. 2013 Sep;56:283-97. doi: 10.1016/j.mcn.2013.07.002. Epub 2013 Jul 10.

Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle

Authors:
Moylan JS, Smith JD, Wolf Horrell EM, McLean JB, Deevska GM, Bonnell MR, Nikolova-Karakashian MN, Reid MB
Citation:
Redox Biol. 2014 Jul 30;2:910-20. doi: 10.1016/j.redox.2014.07.006. eCollection 2014
Epub:
Not Epub
Abstract:
AIMS: Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse myotubes
Citation Extract:
Moylan JS, Smith JD, Wolf Horrell EM, McLean JB, Deevska GM, Bonnell MR, Nikolova-Karakashian MN, Reid MB. Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle. Redox Biol. 2014 Jul 30;2:910-20. doi: 10.1016/j.redox.2014.07.006. eCollection 2014.

Cadm4 restricts the production of cardiac outflow tract progenitor cells

Authors:
Zeng XX, Yelon D
Citation:
Cell Rep. 2014 May 22;7(4):951-60. doi: 10.1016/j.celrep.2014.04.013. Epub 2014 May 9
Epub:
Not Epub
Abstract:
Heart assembly requires input from two populations of progenitor cells, the first and second heart fields (FHF and SHF), that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zeng XX, Yelon D. Cadm4 restricts the production of cardiac outflow tract progenitor cells. Cell Rep. 2014 May 22;7(4):951-60. doi: 10.1016/j.celrep.2014.04.013. Epub 2014 May 9.

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