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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Cardiac BAF complex promotes cardiac progenitors in the zebrafish embryo

Authors:
Scott IC, Lou X
Citation:
Dev Biol. 2010;344(1):413 doi:10.1016/j.ydbio.2010.05.026
Epub:
Not Epub
Abstract:
Little is known about the earliest events that regulate the behaviour of cardiac progenitor cells fated to form the heart. BAF...
Link:
http://www.sciencedirect.com/science/article/pii/S001216061000312X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Scott IC, Lou X. Cardiac BAF complex promotes cardiac progenitors in the zebrafish embryo. Dev Biol. 2010;344(1):413 doi:10.1016/j.ydbio.2010.05.026.

Arhgap36-dependent activation of Gli transcription factors

Authors:
Rack PG, Ni J, Payumo AY, Nguyen V, Crapster JA, Hovestadt V, Kool M, Jones DT, Mich JK, Firestone AJ, Pfister SM, Cho YJ, Chen JK
Citation:
Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11061-6. doi: 10.1073/pnas.1322362111. Epub 2014 Jul 14
Epub:
Not Epub
Abstract:
Hedgehog (Hh) pathway activation and Gli-dependent transcription play critical roles in embryonic patterning, tissue...
Link:
http://www.pnas.org/content/111/30/11061.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rack PG, Ni J, Payumo AY, Nguyen V, Crapster JA, Hovestadt V, Kool M, Jones DT, Mich JK, Firestone AJ, Pfister SM, Cho YJ, Chen JK. Arhgap36-dependent activation of Gli transcription factors. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11061-6. doi: 10.1073/pnas.1322362111. Epub 2014 Jul 14.

Hira-Mediated H3.3 Incorporation Is Required for DNA Replication and Ribosomal RNA Transcription in the Mouse Zygote

Authors:
Lin C-J, Koh FM, Wong P, Conti M, Ramalho-Santos M
Citation:
Dev Cell. 2014;[Epub ahead of print] doi:10.1016/j.devcel.2014.06.022
Epub:
Yes
Abstract:
Extensive chromatin reprogramming occurs at fertilization and is thought to be under the control of maternal factors, but the...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900411-0
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Lin C-J, Koh FM, Wong P, Conti M, Ramalho-Santos M. Hira-Mediated H3.3 Incorporation Is Required for DNA Replication and Ribosomal RNA Transcription in the Mouse Zygote. Dev Cell. 2014;[Epub ahead of print] doi:10.1016/j.devcel.2014.06.022.

RIG-I knockdown impedes neurogenesis in a murine model of Japanese encephalitis

Authors:
Mukherjee S, Ghosh S, Nazmi A, Basu A
Citation:
Cell Biol Int. 2014 Jul 31. doi: 10.1002/cbin.10354. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid inducible gene I (RIG-I) is a well established pattern recognition receptor (PRR) in neurons for Japanese...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/cbin.10354/abstract
Delivery Method:
intracerebral injection in mice
Organism or Cell Type:
Balb/c mice and cell culture: murine neurospheres
Citation Extract:
Mukherjee S, Ghosh S, Nazmi A, Basu A. RIG-I knockdown impedes neurogenesis in a murine model of Japanese encephalitis. Cell Biol Int. 2014 Jul 31. doi: 10.1002/cbin.10354. [Epub ahead of print].

Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway

Authors:
Saita S, Shirane M, Ishitani T, Shimizu N, Nakayama KI
Citation:
J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.558635
Epub:
Yes
Abstract:
Sonic hedgehog (Shh) is a secreted morphogen that controls the patterning and growth of various tissues in the developing...
Link:
http://www.jbc.org/content/early/2014/07/30/jbc.M114.558635.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saita S, Shirane M, Ishitani T, Shimizu N, Nakayama KI. Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway. J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.558635.

myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis

Authors:
Goljanek-Whysall K, Mok GF, Alrefaei AF, Kennerley N, Wheeler GN, Münsterberg A
Citation:
Development. 2014;[Epub ahead of print] doi:10.1242/dev.108787
Epub:
Yes
Abstract:
Myogenesis involves the stable commitment of progenitor cells followed by the execution of myogenic differentiation, processes...
Link:
http://dev.biologists.org/content/early/2014/07/30/dev.108787.abstract
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Goljanek-Whysall K, Mok GF, Alrefaei AF, Kennerley N, Wheeler GN, Münsterberg A. myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis. Development. 2014;[Epub ahead of print] doi:10.1242/dev.108787.

Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies

Authors:
Sud R, Geller ET, Schellenberg GD
Citation:
Mol Ther Nucleic Acids. 2014 Oct 21;3:e204. doi: 10.1038/mtna.2014.55
Epub:
Not Epub
Abstract:
In Alzheimer's disease, progressive supranuclear palsy, and a number of other neurodegenerative diseases, the microtubule...
Link:
http://www.nature.com/mtna/journal/v3/n7/full/mtna201430a.html
Delivery Method:
electroporation in cultures, Vivo-Morpholinos in mice
Organism or Cell Type:
mice, cell culture: human neuroblastoma SH-SY5Y & IMR32
Citation Extract:
Sud R, Geller ET, Schellenberg GD. Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies. Mol Ther Nucleic Acids. 2014 Oct 21;3:e204. doi: 10.1038/mtna.2014.55.

Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1

Authors:
Werner ME, Mitchell JW, Putzbach W, Bacon E, Kim SK, Mitchell BJ
Citation:
J Cell Biol. 2014 Jul 28. pii: jcb.201312045. [Epub ahead of print]
Epub:
Yes
Abstract:
The directed movement of cells is critical for numerous developmental and disease processes. A developmentally reiterated form...
Link:
http://jcb.rupress.org/content/early/2014/07/22/jcb.201312045
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Werner ME, Mitchell JW, Putzbach W, Bacon E, Kim SK, Mitchell BJ. Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1. J Cell Biol. 2014 Jul 28. pii: jcb.201312045. [Epub ahead of print].

Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing

Authors:
Yamazoe S, McQuade LE, Chen JK
Citation:
ACS Chem Biol. 2014 Jul 28. [Epub ahead of print]
Epub:
Yes
Abstract:
Phosphorodiamidate morpholino oligonucleotides are widely used to interrogate gene function in whole organisms, and light-...
Link:
http://pubs.acs.org/doi/abs/10.1021/cb500429u
Organism or Cell Type:
zebrafish
Citation Extract:
Yamazoe S, McQuade LE, Chen JK. Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing. ACS Chem Biol. 2014 Jul 28. [Epub ahead of print].

Cardiac responses to hypercapnia in larval zebrafish (Danio rerio): The links between CO2 chemoreception, catecholamines and carbonic anhydrase

Authors:
Miller S, Pollack J, Bradshaw J, Kumai Y, Perry SF
Citation:
J Exp Biol. 2014 Jul 25. pii: jeb.107987. [Epub ahead of print]
Epub:
Yes
Abstract:
The ontogeny of carbon dioxide (CO2) sensing in zebrafish (Danio rerio) has not been examined. In this study, CO2-mediated...
Link:
http://jeb.biologists.org/content/early/2014/07/23/jeb.107987.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miller S, Pollack J, Bradshaw J, Kumai Y, Perry SF. Cardiac responses to hypercapnia in larval zebrafish (Danio rerio): The links between CO2 chemoreception, catecholamines and carbonic anhydrase. J Exp Biol. 2014 Jul 25. pii: jeb.107987. [Epub ahead of print].

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