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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
An Otx/Nodal Regulatory Signature for Posterior Neural Development in Ascidians
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Citation:
PLoS Genet. 2014;10(8):e1004548. doi:10.1371/journal.pgen.1004548 Epub:
Not Epub Abstract:
In chordates, neural induction is the first step of a complex developmental process through which ectodermal cells acquire a... Link:
Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis Citation Extract: Roure A, Lemaire P, Darras S. An Otx/Nodal Regulatory Signature for Posterior Neural Development in Ascidians. PLoS Genet. 2014;10(8):e1004548. doi:10.1371/journal.pgen.1004548. |
CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration
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Citation:
Stem Cell Rep. 2014 Sep 9;3(3):444-59. doi: 10.1016/j.stemcr.2014.06.018. Epub 2014 Aug 7. Epub:
Not Epub Abstract:
The salamander is the only tetrapod that functionally regenerates all cell types of the limb and spinal cord (SC) and thus... Delivery Method:
microinjection Organism or Cell Type:
Ambystoma mexicanum (axolotl) Citation Extract: Fei J-F, Schuez M, Tazaki A, Taniguchi Y, Roensch K, Tanaka EM. CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration. Stem Cell Rep. 2014 Sep 9;3(3):444-59. doi: 10.1016/j.stemcr.2014.06.018. Epub 2014 Aug 7.. |
A Heroin Addiction Severity-Associated Intronic Single Nucleotide Polymorphism Modulates Alternative Pre-mRNA Splicing of the μ Opioid Receptor Gene OPRM1 via hnRNPH Interactions
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Citation:
J Neurosci. 2014;34(33):11048-66. doi:10.1523/JNEUROSCI.3986-13.2014 Epub:
Not Epub Abstract:
Single nucleotide polymorphisms (SNPs) in the OPRM1 gene have been associated with vulnerability to opioid dependence. The... Organism or Cell Type:
cell culture Citation Extract: Xu J, Lu Z, Xu M, Pan L, Deng Y, Xie X, Liu H, Ding S, Hurd YL, Pasternak GW, Klein RJ, Cartegni L, Zhou W, Pan Y-X. A Heroin Addiction Severity-Associated Intronic Single Nucleotide Polymorphism Modulates Alternative Pre-mRNA Splicing of the μ Opioid Receptor Gene OPRM1 via hnRNPH Interactions. J Neurosci. 2014;34(33):11048-66. doi:10.1523/JNEUROSCI.3986-13.2014. |
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model
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Citation:
J Clin Invest. 2014 Aug 8. pii: 76175. doi: 10.1172/JCI76175. [Epub ahead of print] Epub:
Yes Abstract:
X-linked agammaglobulinemia (XLA) is an inherited immunodeficiency that results from mutations within the gene encoding Bruton... Delivery Method:
Peptide-linked or bare oligo Organism or Cell Type:
mice, cell culture: U2OS reporter cell line Citation Extract: Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Piątosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin KE, El Andaloussi S, Månsson R, Berglöf A, Wengel J, Smith CI. Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. J Clin Invest. 2014 Aug 8. pii: 76175. doi: 10.1172/JCI76175. [Epub ahead of print]. |
Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1
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Citation:
Nature. 2014;[Epub ahead of print] doi:10.1038/nature13678 Epub:
Yes Abstract:
Haematopoietic stem cells (HSCs) are self-renewing stem cells capable of replenishing all blood lineages. In all vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nguyen PD, Hollway GE, Sonntag C, Miles LB, Hall TE, Berger S, Fernandez KJ, Gurevich DB, Cole NJ, Alaei S, Ramialison M, Sutherland RL, Polo JM, Lieschke GJ, Currie PD. Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1. Nature. 2014;[Epub ahead of print] doi:10.1038/nature13678. |
L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way
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Citation:
Brit J Haematol. 2014;[Epub ahead of print] doi:10.1111/bjh.13069 Epub:
Yes Abstract:
Haploinsufficiency of ribosomal proteins (RPs) and upregulation of the tumour suppressor TP53 have been shown to be the common... Organism or Cell Type:
zebrafish Citation Extract: Narla A, Payne EM, Abayasekara N, Hurst SN, Raiser DM, Look AT, Berliner N, Ebert BL Khanna-Gupta A. L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way. Brit J Haematol. 2014;[Epub ahead of print] doi:10.1111/bjh.13069. |
Deadenylase depletion protects inherited mRNAs in primordial germ cells
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Citation:
Development. 2014;141:3134-42. doi:10.1242/dev.110395 Epub:
Not Epub Abstract:
A crucial event in animal development is the specification of primordial germ cells (PGCs), which become the stem cells that... Delivery Method:
microinjection Organism or Cell Type:
Sea urchin Strongylocentrotus purpuratus Citation Extract: Swartz SZ, Reich AM, Oulhen N, Raz T, Milos PM, Campanale JP, Hamdoun A, Wessel GM. Deadenylase depletion protects inherited mRNAs in primordial germ cells. Development. 2014;141:3134-42. doi:10.1242/dev.110395. |
Kremen1 restricts Dkk activity during posterior lateral line development in zebrafish
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Citation:
Development. 2014 Jul 18. pii: dev.102541. [Epub ahead of print] Epub:
Yes Abstract:
Canonical Wnt signaling plays crucial roles during development and disease. How Wnt signaling is modulated in different in vivo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: McGraw HF, Culbertson MD, Nechiporuk AV. Kremen1 restricts Dkk activity during posterior lateral line development in zebrafish. Development. 2014 Jul 18. pii: dev.102541. [Epub ahead of print]. |
Temporal control over the initiation of cell motility by a regulator of G-protein signaling
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Citation:
Proc Natl Acad Sci U S A. 2014 Jul 21. pii: 201400043. [Epub ahead of print] Epub:
Yes Abstract:
The control over the acquisition of cell motility is central for a variety of biological processes in development, homeostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hartwig J, Tarbashevich K, Seggewiß J, Stehling M, Bandemer J, Grimaldi C, Paksa A, Groß-Thebing T, Meyen D, Raz E. Temporal control over the initiation of cell motility by a regulator of G-protein signaling. Proc Natl Acad Sci U S A. 2014 Jul 21. pii: 201400043. [Epub ahead of print]. |
Whitesnake/sfpq is required for cell survival and neuronal development in the zebrafish
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Citation:
Dev Dyn. 2007 May;236(5):1347-57. Erratum in: Dev Dyn. 2008 Mar;237(3):859 Epub:
Not Epub Abstract:
Organogenesis involves both the development of specific cell types and their organization into a functional three-dimensional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lowery LA, Rubin J, Sive H. Whitesnake/sfpq is required for cell survival and neuronal development in the zebrafish. Dev Dyn. 2007 May;236(5):1347-57. Erratum in: Dev Dyn. 2008 Mar;237(3):859. |