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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency
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Citation:
Haemophilia. 2014 Dec 3. doi: 10.1111/hae.12554. [Epub ahead of print] Epub:
Yes Abstract:
Coagulation factor V (FV) deficiency is a rare autosomal recessive bleeding disorder. We investigated a patient with severe FV... Citation Extract: Nuzzo F, Bulato C, Nielsen BI, Lee K, Wielders SJ, Simioni P, Key NS, Castoldi E. Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency. Haemophilia. 2014 Dec 3. doi: 10.1111/hae.12554. [Epub ahead of print]. |
Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts
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Citation:
FASEB J. 2014 Dec 2. pii: fj.14-261131. [Epub ahead of print] Epub:
Yes Abstract:
The embryonic pattern of global DNA methylation is first established in the inner cell mass (ICM) of the mouse blastocyst. The... Delivery Method:
Lipofectin Organism or Cell Type:
Eight-cell stage mouse embryos Citation Extract: Zhang B, Denomme MM, White CR, Leung KY, Lee MB, Greene ND, Mann MR, Trasler JM, Baltz JM. Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts. FASEB J. 2014 Dec 2. pii: fj.14-261131. [Epub ahead of print]. |
DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10
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Citation:
Proc Natl Acad Sci U S A. 2014 Dec 1. pii: 201318408. [Epub ahead of print] Epub:
Yes Abstract:
Neural crest stem cells arise within the central nervous system but then undergo an epithelial-to-mesenchymal transition to... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hu N, Strobl-Mazzulla PH, Simoes-Costa M, Sánchez-Vásquez E, Bronner ME. DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10. Proc Natl Acad Sci U S A. 2014 Dec 1. pii: 201318408. [Epub ahead of print]. |
Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta
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Citation:
Dev Biol. 2014 Oct 14. pii: S0012-1606(14)00502-8. doi: 10.1016/j.ydbio.2014.08.038. [Epub ahead of print] Epub:
Yes Abstract:
The zebrafish pronephros provides an excellent in vivo system to study the mechanisms of vertebrate nephron development. When... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gerlach GF, Wingert RA. Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta. Dev Biol. 2014 Oct 14. pii: S0012-1606(14)00502-8. doi: 10.1016/j.ydbio.2014.08.038. [Epub ahead of print]. |
Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development
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Citation:
Dev Biol. 2014 Nov 8. pii: S0012-1606(14)00563-6. doi: 10.1016/j.ydbio.2014.10.022. [Epub ahead of print] Epub:
Yes Abstract:
The respective role of Pax2 and Pax8 in early kidney development in vertebrates is poorly understood. In this report, we have... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Buisson I, le Bouffant R, Futel M, Riou JF, Umbhauer M. Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development. Dev Biol. 2014 Nov 8. pii: S0012-1606(14)00563-6. doi: 10.1016/j.ydbio.2014.10.022. [Epub ahead of print]. |
The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis
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Citation:
Dev Biol. 2014 Nov 1. pii: S0012-1606(14)00559-4. doi: 10.1016/j.ydbio.2014.10.018. [Epub ahead of print] Epub:
Yes Abstract:
The study of molecular regulation in neural development provides information to understand how diverse neural cells are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng YC, Chiang MC, Shih HY, Ma TL, Yeh TH, Huang YC, Lin CY, Lin SJ. The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis. Dev Biol. 2014 Nov 1. pii: S0012-1606(14)00559-4. doi: 10.1016/j.ydbio.2014.10.018. [Epub ahead of print]. |
Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis
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Citation:
Dev Biol. 2014 Oct 31. pii: S0012-1606(14)00558-2. doi: 10.1016/j.ydbio.2014.10.017. [Epub ahead of print] Epub:
Yes Abstract:
During brain morphogenesis, the neuroepithelium must fold in specific regions to delineate functional units, and give rise to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gutzman JH, Sahu SU, Kwas C. Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis. Dev Biol. 2014 Oct 31. pii: S0012-1606(14)00558-2. doi: 10.1016/j.ydbio.2014.10.017. [Epub ahead of print]. |
Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development
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Citation:
Development. 2014;141:4794-805. doi:10.1242/dev.115691 Epub:
Not Epub Abstract:
Brain regionalisation, neuronal subtype diversification and circuit connectivity are crucial events in the establishment of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Zhang S, Li J, Lea R, Vleminckx K, Amaya E. Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development. Development. 2014;141:4794-805. doi:10.1242/dev.115691. |
A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys
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Citation:
J Vis Exp. 2014;94:e52156. doi:10.3791/52156 Epub:
Not Epub Abstract:
Polycystic kidney disease (PKD) is one of the most common causes of end-stage kidney disease, a devastating disease for which... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang L, Xiao A, Wecker A, McBride DA, Choi SY, Zhou W, Lipschutz JH. A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys. J Vis Exp. 2014;94:e52156. doi:10.3791/52156. |
Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy
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Citation:
Nucl Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2 Epub:
Not Epub Abstract:
The potential for therapeutic application of splice-switching oligonucleotides (SSOs) to modulate pre-mRNA splicing is... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: mouse H2K/mdx myotubes, mice (mdx) Citation Extract: Shabanpoor F, McClorey G, Saleh AF, Järver P, Wood MJA, Gait MJ. Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy. Nucl Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2. |