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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Blood flow and bmp signaling control endocardial chamber morphogenesis

Authors:
Dietrich AC, Lombardo VA, Abdelilah-Seyfried S
Citation:
Dev Cell. 2014 Aug 25;30(4):367-77. doi: 10.1016/j.devcel.2014.06.020
Epub:
Not Epub
Abstract:
During heart development, the onset of heartbeat and blood flow coincides with a ballooning of the cardiac chambers. Here, we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dietrich AC, Lombardo VA, Abdelilah-Seyfried S. Blood flow and bmp signaling control endocardial chamber morphogenesis. Dev Cell. 2014 Aug 25;30(4):367-77. doi: 10.1016/j.devcel.2014.06.020.

The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish

Authors:
Young T, Poobalan Y, Tan EK, Tao S, Ong S, Wehner P, Schwenty-Lara J, Lim CY, Sadasivam A, Lovatt M, Wang ST, Ali Y, Borchers A, Sampath K, Dunn NR
Citation:
Development. 2014;141:3505-16; doi:10.1242/dev.114033
Epub:
Not Epub
Abstract:
During vertebrate gastrulation, a complex set of mass cellular rearrangements shapes the embryonic body plan and appropriately...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young T, Poobalan Y, Tan EK, Tao S, Ong S, Wehner P, Schwenty-Lara J, Lim CY, Sadasivam A, Lovatt M, Wang ST, Ali Y, Borchers A, Sampath K, Dunn NR. The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish. Development. 2014;141:3505-16; doi:10.1242/dev.114033.

DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia

Authors:
Markham NO, Doll CA, Dohn MR, Miller RK, Yu H, Coffey RJ, McCrea PD, Gamse JT, Reynolds AB
Citation:
Mol Biol Cell. 2014 Sep 1;25(17):2592-603. doi: 10.1091/mbc.E13-08-0492. Epub 2014 Jul 9
Epub:
Not Epub
Abstract:
p120-catenin (p120) modulates adherens junction (AJ) dynamics by controlling the stability of classical cadherins. Among all...
Organism or Cell Type:
zebrafish
Citation Extract:
Markham NO, Doll CA, Dohn MR, Miller RK, Yu H, Coffey RJ, McCrea PD, Gamse JT, Reynolds AB. DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Mol Biol Cell. 2014 Sep 1;25(17):2592-603. doi: 10.1091/mbc.E13-08-0492. Epub 2014 Jul 9.

Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization

Authors:
Kizil C, Küchler B, Yan J-J, Özhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL
Citation:
Development. 2014;141:3529-39. doi:10.1242/dev.108415
Epub:
Not Epub
Abstract:
Canonical β-catenin-dependent Wnt signal transduction is important for several biological phenomena, such as cell fate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kizil C, Küchler B, Yan J-J, Özhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL. Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development. 2014;141:3529-39. doi:10.1242/dev.108415.

Zebrafish WNK Lysine Deficient Protein Kinase 1 (wnk1) Affects Angiogenesis Associated with VEGF Signaling

Authors:
Lai JG, Tsai SM, Tu HC, Chen WC, Kou FJ, Lu JW, Wang HD, Huang CL, Yuh CH
Citation:
PLoS One. 2014 Aug 29;9(8):e106129. doi: 10.1371/journal.pone.0106129. eCollection 2014
Epub:
Not Epub
Abstract:
The WNK1 (WNK lysine deficient protein kinase 1) protein is a serine/threonine protein kinase with emerging roles in cancer....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JG, Tsai SM, Tu HC, Chen WC, Kou FJ, Lu JW, Wang HD, Huang CL, Yuh CH. Zebrafish WNK Lysine Deficient Protein Kinase 1 (wnk1) Affects Angiogenesis Associated with VEGF Signaling. PLoS One. 2014 Aug 29;9(8):e106129. doi: 10.1371/journal.pone.0106129. eCollection 2014.

Rbm24a and Rbm24b Are Required for Normal Somitogenesis

Authors:
Maragh S, Miller RA, Bessling SL, Wang G, Hook PW, McCallion AS
Citation:
PLoS One. 2014 Aug 29;9(8):e105460. doi: 10.1371/journal.pone.0105460. eCollection 2014
Epub:
Not Epub
Abstract:
We recently demonstrated that the gene encoding the RNA binding motif protein 24 (RBM24) is expressed during mouse...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maragh S, Miller RA, Bessling SL, Wang G, Hook PW, McCallion AS. Rbm24a and Rbm24b Are Required for Normal Somitogenesis. PLoS One. 2014 Aug 29;9(8):e105460. doi: 10.1371/journal.pone.0105460. eCollection 2014.

Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish

Authors:
Ogai K, Kuwana A, Hisano S, Nagashima M, Koriyama Y, Sugitani K, Mawatari K, Nakashima H, Kato S
Citation:
PLoS One. 2014 Aug 27;9(8):e106010. doi: 10.1371/journal.pone.0106010. eCollection 2014
Epub:
Not Epub
Abstract:
Fish retinal ganglion cells (RGCs) can regenerate their axons after optic nerve injury, whereas mammalian RGCs normally fail to...
Delivery Method:
gelatin foam at injury site
Organism or Cell Type:
zebrafish
Citation Extract:
Ogai K, Kuwana A, Hisano S, Nagashima M, Koriyama Y, Sugitani K, Mawatari K, Nakashima H, Kato S. Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish. PLoS One. 2014 Aug 27;9(8):e106010. doi: 10.1371/journal.pone.0106010. eCollection 2014.

Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish

Authors:
Wu BJ, Chiu CC, Chen CL, Wang WD, Wang JH, Wen ZH, Liu W, Chang HW, Wu CY
Citation:
PLoS One. 2014 Aug 26;9(8):e105939. doi: 10.1371/journal.pone.0105939. eCollection 2014
Epub:
Not Epub
Abstract:
Genetic regulators and signaling pathways are important for the formation of blood vessels. Transcription factors controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu BJ, Chiu CC, Chen CL, Wang WD, Wang JH, Wen ZH, Liu W, Chang HW, Wu CY. Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish. PLoS One. 2014 Aug 26;9(8):e105939. doi: 10.1371/journal.pone.0105939. eCollection 2014.

Ncor1 and Ncor2 Play essential but distinct roles in zebrafish primitive myelopoiesis

Authors:
Li J, Li K, Dong X, Liang D, Zhao Q
Citation:
Dev Dyn. 2014 Aug 26. doi: 10.1002/dvdy.24181. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Though Ncor1 and Ncor2, the co-repressors that can actively repress gene transcription through binding nuclear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Li K, Dong X, Liang D, Zhao Q. Ncor1 and Ncor2 Play essential but distinct roles in zebrafish primitive myelopoiesis. Dev Dyn. 2014 Aug 26. doi: 10.1002/dvdy.24181. [Epub ahead of print].

Safety and Pharmacokinetic Profiles of Phosphorodiamidate Morpholino Oligomers with Activity against Ebola Virus and Marburg Virus: Results of Two Single Ascending Dose Studies

Authors:
Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E
Citation:
Antimicrob Agents Chemother. 2014 Aug 25. pii: AAC.03442-14. [Epub ahead of print]
Epub:
Yes
Abstract:
Two identical single ascending dose (SAD) studies evaluated the safety and pharmacokinetics (PK) of AVI-6002 and AVI-6003, two...
Delivery Method:
iv infusion
Organism or Cell Type:
human
Citation Extract:
Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E. Safety and Pharmacokinetic Profiles of Phosphorodiamidate Morpholino Oligomers with Activity against Ebola Virus and Marburg Virus: Results of Two Single Ascending Dose Studies. Antimicrob Agents Chemother. 2014 Aug 25. pii: AAC.03442-14. [Epub ahead of print].

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