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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Formin-Mediated Actin Polymerization at Endothelial Junctions Is Required for Vessel Lumen Formation and Stabilization

Authors:
Phng L-K, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting H-G, Affolter M, Gerhardt H
Citation:
Dev Cell. 2015;32(1):123-32. doi:10.1016/j.devcel.2014.11.017
Epub:
Not Epub
Abstract:
During blood vessel formation, endothelial cells (ECs) establish cell-cell junctions and rearrange to form multicellular tubes...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900734-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Phng L-K, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting H-G, Affolter M, Gerhardt H. Formin-Mediated Actin Polymerization at Endothelial Junctions Is Required for Vessel Lumen Formation and Stabilization. Dev Cell. 2015;32(1):123-32. doi:10.1016/j.devcel.2014.11.017.

Making Sense of Anti-Sense Data

Authors:
Stainier DYR, Kontarakis Z, Rossi A
Citation:
Dev Cell. 2015;32(1)7-8. doi:10.1016/j.devcel.2014.12.012
Epub:
Not Epub
Abstract:
The morpholino anti-sense technology has been used extensively to test gene function. The zebrafish model allows a detailed...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900833-8
Citation Extract:
Stainier DYR, Kontarakis Z, Rossi A. Making Sense of Anti-Sense Data. Dev Cell. 2015;32(1)7-8. doi:10.1016/j.devcel.2014.12.012.

miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins

Authors:
Hudish LI, Blasky AJ, Appel B
Citation:
Dev Cell. 2013 Nov 25;27(4):387-98. doi: 10.1016/j.devcel.2013.10.015. Epub 2013 Nov 14
Epub:
Not Epub
Abstract:
Asymmetric self-renewing division of neural precursors is essential for brain development. Partitioning-defective (Par)...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862977/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hudish LI, Blasky AJ, Appel B. miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins. Dev Cell. 2013 Nov 25;27(4):387-98. doi: 10.1016/j.devcel.2013.10.015. Epub 2013 Nov 14.

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A

Authors:
Ingold E, vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SCF, Gesemann M
Citation:
Bio Open. 2015;[Epub] doi:10.1242/bio.20148482
Epub:
Not Epub
Abstract:
The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors....
Link:
http://bio.biologists.org/content/early/2015/01/04/bio.20148482.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ingold E, vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SCF, Gesemann M. Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A. Bio Open. 2015;[Epub] doi:10.1242/bio.20148482 .

Fgf-Signaling-Dependent Sox9a and Atoh1a Regulate Otic Neural Development in Zebrafish

Authors:
Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, Zhu Z, Liu D
Citation:
J Neurosci. 2015;35(1):234-244. doi:10.1523/JNEUROSCI.3353-14.2015
Epub:
Not Epub
Abstract:
Fibroblast growth factors (Fgfs) play important roles in developmental processes of the inner ear, including the ontogeny of...
Link:
http://www.jneurosci.org/content/35/1/234.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, Zhu Z, Liu D. Fgf-Signaling-Dependent Sox9a and Atoh1a Regulate Otic Neural Development in Zebrafish. J Neurosci. 2015;35(1):234-244. doi:10.1523/JNEUROSCI.3353-14.2015.

Myoinhibitory peptide regulates feeding in the marine annelid Platynereis

Authors:
Williams EA, Conzelmann M, Jékely G
Citation:
Front Zool. 2015;[Epub ahead of print] doi:10.1186/s12983-014-0093-6
Epub:
Yes
Abstract:
Background: During larval settlement and metamorphosis, marine invertebrates undergo changes in habitat, morphology, behavior...
Link:
http://www.frontiersinzoology.com/content/12/1/1/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Platyneris dumerilii (annelid)
Citation Extract:
Williams EA, Conzelmann M, Jékely G. Myoinhibitory peptide regulates feeding in the marine annelid Platynereis. Front Zool. 2015;[Epub ahead of print] doi:10.1186/s12983-014-0093-6.

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

Authors:
Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O’ Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL
Citation:
J Med Genet. 2015 Mar;52(3):147-56. doi: 10.1136/jmedgenet-2014-102691. Epub 2015 Jan 6
Epub:
Not Epub
Abstract:
Background: Mutations in microtubule-regulating genes are associated with disorders of neuronal migration and microcephaly....
Link:
http://jmg.bmj.com/content/early/2015/01/06/jmedgenet-2014-102691.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O’ Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL. The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes. J Med Genet. 2015 Mar;52(3):147-56. doi: 10.1136/jmedgenet-2014-102691. Epub 2015 Jan 6.

Mutations in RAD21 Disrupt Regulation of APOB in Patients with Chronic Intestinal Pseudo-obstruction

Authors:
Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, Stanghellini V, Cogliandro RF, Lindberg G, Mungan Z, Cefle K, Ozcelik T, Palanduz S, Ozturk S, Gedikbasi A, Gori A, Pippucci T, Graziano C, Volta U, Caio G, Barbara G, D'Amato M, Seri M, Katsanis N, Romeo G, De Giorgio R
Citation:
Gastroenterology. 2014;[Epub ahead of print] doi:10.1053/j.gastro.2014.12.034
Epub:
Yes
Abstract:
Background & Aims: Chronic intestinal pseudo-obstruction (CIPO) is characterized by severe intestinal dysmotility that...
Link:
http://www.gastrojournal.org/article/S0016-5085%2815%2900010-4/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, Stanghellini V, Cogliandro RF, Lindberg G, Mungan Z, Cefle K, Ozcelik T, Palanduz S, Ozturk S, Gedikbasi A, Gori A, Pippucci T, Graziano C, Volta U, Caio G, Barbara G, D'Amato M, Seri M, Katsanis N, Romeo G, De Giorgio R. Mutations in RAD21 Disrupt Regulation of APOB in Patients with Chronic Intestinal Pseudo-obstruction. Gastroenterology. 2014;[Epub ahead of print] doi:10.1053/j.gastro.2014.12.034.

Sox4 regulates choroid fissure closure by limiting hedgehog signaling during ocular morphogenesis

Authors:
Wen W, Pillai-Kastoori L, Wilson SG, Morris AC
Citation:
Dev Biol. 2014 Dec 31. pii: S0012-1606(14)00667-8. doi: 10.1016/j.ydbio.2014.12.026. [Epub ahead of print]
Epub:
Yes
Abstract:
SoxC transcription factors play critical roles in many developmental processes, including neurogenesis, cardiac formation, and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614006678
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wen W, Pillai-Kastoori L, Wilson SG, Morris AC. Sox4 regulates choroid fissure closure by limiting hedgehog signaling during ocular morphogenesis. Dev Biol. 2014 Dec 31. pii: S0012-1606(14)00667-8. doi: 10.1016/j.ydbio.2014.12.026. [Epub ahead of print].

Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages

Authors:
Nagendran M, Arora P, Gori P, Mulay A, Ray S, Jacob T, Sonawane M
Citation:
Development. 2015;142:320-330. doi:10.1242/dev.118703
Epub:
Not Epub
Abstract:
Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. The...
Link:
http://dev.biologists.org/content/142/2/320
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nagendran M, Arora P, Gori P, Mulay A, Ray S, Jacob T, Sonawane M. Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development. 2015;142:320-330. doi:10.1242/dev.118703 .

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