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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

Authors:
Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW
Citation:
Dev Biol. 2014 Sep 11. pii: S0012-1606(14)00451-5. doi: 10.1016/j.ydbio.2014.09.008. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt signaling and ciliogenesis are core features of embryonic development in a range of metazoans. Chibby (Cby), a basal-body...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression. Dev Biol. 2014 Sep 11. pii: S0012-1606(14)00451-5. doi: 10.1016/j.ydbio.2014.09.008. [Epub ahead of print].

A sensitive assay system to test antisense oligonucleotides for splice suppression therapy in the mouse liver

Authors:
Gallego-Villar L, Viecelli HM, Pérez B, Harding CO, Ugarte M, Thöny B, Desviat LR
Citation:
Mol Ther Nucleic Acids. 2014 Sep 16;3:e193. doi: 10.1038/mtna.2014.44
Epub:
Not Epub
Abstract:
We have previously demonstrated the efficacy of antisense therapy for splicing defects in cellular models of metabolic diseases...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Gallego-Villar L, Viecelli HM, Pérez B, Harding CO, Ugarte M, Thöny B, Desviat LR. A sensitive assay system to test antisense oligonucleotides for splice suppression therapy in the mouse liver. Mol Ther Nucleic Acids. 2014 Sep 16;3:e193. doi: 10.1038/mtna.2014.44.

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character

Authors:
Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM
Citation:
Dev Biol. 2014 Sep 12. pii: S0012-1606(14)00447-3. doi: 10.1016/j.ydbio.2014.09.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The retinal anterior homeobox (rax) gene encodes a transcription factor necessary for vertebrate eye development. rax...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM. Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character. Dev Biol. 2014 Sep 12. pii: S0012-1606(14)00447-3. doi: 10.1016/j.ydbio.2014.09.004. [Epub ahead of print].

Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells

Authors:
Wen L, Yang Y, Wang Y, Xu A, Wu D, Chen Y
Citation:
Dev Dyn. 2010 Aug;239(8):2198-207. doi: 10.1002/dvdy.22356
Epub:
Not Epub
Abstract:
An understanding of the molecular mechanisms governing the survival of organ progenitor cells in vivo is crucial for in vitro...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wen L, Yang Y, Wang Y, Xu A, Wu D, Chen Y. Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. Dev Dyn. 2010 Aug;239(8):2198-207. doi: 10.1002/dvdy.22356.

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells

Authors:
Lam EY, Hall CJ, Crosier PS, Crosier KE, Flores MV
Citation:
Blood. 2010 Aug 12;116(6):909-14. doi: 10.1182/blood-2010-01-264382. Epub 2010 May 7
Epub:
Not Epub
Abstract:
Blood cells of an adult vertebrate are continuously generated by hematopoietic stem cells (HSCs) that originate during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lam EY, Hall CJ, Crosier PS, Crosier KE, Flores MV. Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells. Blood. 2010 Aug 12;116(6):909-14. doi: 10.1182/blood-2010-01-264382. Epub 2010 May 7.

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties

Authors:
Flores MV, Crawford KC, Pullin LM, Hall CJ, Crosier KE, Crosier PS
Citation:
Biochem Biophys Res Commun. 2010 Sep 10;400(1):164-8. doi: 10.1016/j.bbrc.2010.08.037. Epub 2010 Aug 13
Epub:
Not Epub
Abstract:
Reactive oxygen species (ROS) function in a range of physiological processes such as growth, metabolism and signaling, and also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flores MV, Crawford KC, Pullin LM, Hall CJ, Crosier KE, Crosier PS . Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties. Biochem Biophys Res Commun. 2010 Sep 10;400(1):164-8. doi: 10.1016/j.bbrc.2010.08.037. Epub 2010 Aug 13.

KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation

Authors:
Alves MM, Burzynski G, Delalande JM, Osinga J, van der Goot A, Dolga AM, de Graaff E, Brooks AS, Metzger M, Eisel UL, Shepherd I, Eggen BJ, Hofstra RM
Citation:
Hum Mol Genet. 2010 Sep 15;19(18):3642-51. doi: 10.1093/hmg/ddq280. Epub 2010 Jul 9
Epub:
Not Epub
Abstract:
Goldberg-Shprintzen syndrome (GOSHS) is a rare clinical disorder characterized by central and enteric nervous system defects....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alves MM, Burzynski G, Delalande JM, Osinga J, van der Goot A, Dolga AM, de Graaff E, Brooks AS, Metzger M, Eisel UL, Shepherd I, Eggen BJ, Hofstra RM. KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation. Hum Mol Genet. 2010 Sep 15;19(18):3642-51. doi: 10.1093/hmg/ddq280. Epub 2010 Jul 9.

Depletion of the IKBKAP ortholog in zebrafish leads to Hirschsprung disease-like phenotype

Authors:
Cheng WW-C, Tang CS-M, Gui H-S, So M-T, Lui VC-H, Tam PK-H, Garcia-Barcelo M-M
Citation:
World J Gastroenterol. 2015; 21(7): 2040-6. doi:10.3748/wjg.v21.i7.2040
Epub:
Not Epub
Abstract:
AIM: To investigate the role of IKBKAP (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng WW-C, Tang CS-M, Gui H-S, So M-T, Lui VC-H, Tam PK-H, Garcia-Barcelo M-M. Depletion of the IKBKAP ortholog in zebrafish leads to Hirschsprung disease-like phenotype. World J Gastroenterol. 2015; 21(7): 2040-6. doi:10.3748/wjg.v21.i7.2040.

Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4)

Authors:
Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI
Citation:
Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku805
Epub:
Yes
Abstract:
Recent small RNA sequencing data has uncovered 3′ end modification of mature microRNAs (miRNAs). This non-templated nucleotide...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku805.

Myomaker mediates fusion of fast myocytes in zebrafish embryos

Authors:
Landemaine A, Rescan PY, Gabillard JC
Citation:
Biochem Biophys Res Commun. 2014 Sep 5;451(4):480-484. doi: 10.1016/j.bbrc.2014.07.093. Epub 2014 Jul 28
Epub:
Not Epub
Abstract:
Myomaker (also called Tmem8c), a new membrane activator of myocyte fusion was recently discovered in mice. Using whole mount in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landemaine A, Rescan PY, Gabillard JC. Myomaker mediates fusion of fast myocytes in zebrafish embryos. Biochem Biophys Res Commun. 2014 Sep 5;451(4):480-484. doi: 10.1016/j.bbrc.2014.07.093. Epub 2014 Jul 28.

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