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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development

Authors:
Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF
Citation:
PLoS Genet. 2014;10(9):e1004671. doi:10.1371/journal.pgen.1004671
Epub:
Not Epub
Abstract:
Haploinsufficiency for Nipbl, a cohesin loading protein, causes Cornelia de Lange Syndrome (CdLS), the most common “...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF. Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development. PLoS Genet. 2014;10(9):e1004671. doi:10.1371/journal.pgen.1004671.

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

Authors:
Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C
Citation:
Nat Genet. 2014;[Epub ahead of print] doi:10.1038/ng.3103
Epub:
Yes
Abstract:
Age-related degenerative and malignant diseases represent major challenges for health care systems. Elucidation of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C. Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features. Nat Genet. 2014;[Epub ahead of print] doi:10.1038/ng.3103.

Tbx Protein Level Critical for Clock-Mediated Somite Positioning Is Regulated through Interaction between Tbx and Ripply

Authors:
Wanglar C, Takahashi J, Yabe T, Takada S
Citation:
PLoS ONE. 2014;9(9):e107928. doi:10.1371/journal.pone.0107928
Epub:
Not Epub
Abstract:
Somitogenesis in vertebrates is a complex and dynamic process involving many sequences of events generated from the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wanglar C, Takahashi J, Yabe T, Takada S. Tbx Protein Level Critical for Clock-Mediated Somite Positioning Is Regulated through Interaction between Tbx and Ripply. PLoS ONE. 2014;9(9):e107928. doi:10.1371/journal.pone.0107928.

Variable Combinations of Specific Ephrin Ligand/Eph Receptor Pairs Control Embryonic Tissue Separation

Authors:
Rohani N, Parmeggiani A, Winklbauer R, Fagotto F
Citation:
PLoS Biol. 2014:12(9):e1001955. doi:10.1371/journal.pbio.1001955
Epub:
Not Epub
Abstract:
Ephrins and Eph receptors are involved in the establishment of vertebrate tissue boundaries. The complexity of the system is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Rohani N, Parmeggiani A, Winklbauer R, Fagotto F. Variable Combinations of Specific Ephrin Ligand/Eph Receptor Pairs Control Embryonic Tissue Separation. PLoS Biol. 2014:12(9):e1001955. doi:10.1371/journal.pbio.1001955.

Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration

Authors:
Wan J, Zhao X-F, Vojtek A, Goldman D
Citation:
Cell Rep. 2014 Oct 9;9(1):285-97. doi: 10.1016/j.celrep.2014.08.048. Epub 2014 Sep 25.
Epub:
Not Epub
Abstract:
Müller glia (MG) in the zebrafish retina respond to retinal injury by generating multipotent progenitors for retinal repair....
Delivery Method:
retinal injury & electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Wan J, Zhao X-F, Vojtek A, Goldman D. Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration. Cell Rep. 2014 Oct 9;9(1):285-97. doi: 10.1016/j.celrep.2014.08.048. Epub 2014 Sep 25..

Functional Analysis of SPECC1L in Craniofacial Development and Oblique Facial Cleft Pathogenesis

Authors:
Gfrerer L, Shubinets V, Hoyos T, Kong Y, Nguyen C, Pietschmann P, Morton CC, Maas RL, Liao E
Citation:
Plastic & Reconstruc Surgery. 2014;134(4):748-59. doi: 10.1097/PRS.0000000000000517
Epub:
Not Epub
Abstract:
Background: Oblique facial clefts, also known as Tessier clefts, are severe orofacial clefts, the genetic basis of which is...
Organism or Cell Type:
zebrafish
Citation Extract:
Gfrerer L, Shubinets V, Hoyos T, Kong Y, Nguyen C, Pietschmann P, Morton CC, Maas RL, Liao E. Functional Analysis of SPECC1L in Craniofacial Development and Oblique Facial Cleft Pathogenesis. Plastic & Reconstruc Surgery. 2014;134(4):748-59. doi: 10.1097/PRS.0000000000000517.

The Hemodynamically-Regulated Vascular Microenvironment Promotes Migration of the Steroidogenic Tissue during Its Interaction with Chromaffin Cells in the Zebrafish Embryo

Authors:
Chou CW, Zhuo YL, Jiang ZY, Liu YW
Citation:
PLoS One. 2014 Sep 23;9(9):e107997. doi: 10.1371/journal.pone.0107997. eCollection 2014
Epub:
Not Epub
Abstract:
BACKGROUND: While the endothelium-organ interaction is critical for regulating cellular behaviors during development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou CW, Zhuo YL, Jiang ZY, Liu YW. The Hemodynamically-Regulated Vascular Microenvironment Promotes Migration of the Steroidogenic Tissue during Its Interaction with Chromaffin Cells in the Zebrafish Embryo. PLoS One. 2014 Sep 23;9(9):e107997. doi: 10.1371/journal.pone.0107997. eCollection 2014.

Macrophage-Expressed Perforins Mpeg1 and Mpeg1.2 Have an Anti-Bacterial Function in Zebrafish

Authors:
Benard EL, Racz PI, Rougeot J, Nezhinsky AE, Verbeek FJ, Spaink HP, Meijer AH
Citation:
J Innate Immun. 2015;7(2):136-52. doi: 10.1159/000366103. Epub 2014 Sep 19.
Epub:
Not Epub
Abstract:
Macrophage-expressed gene 1 (MPEG1) encodes an evolutionarily conserved protein with a predicted membrane attack complex/...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Benard EL, Racz PI, Rougeot J, Nezhinsky AE, Verbeek FJ, Spaink HP, Meijer AH. Macrophage-Expressed Perforins Mpeg1 and Mpeg1.2 Have an Anti-Bacterial Function in Zebrafish. J Innate Immun. 2015;7(2):136-52. doi: 10.1159/000366103. Epub 2014 Sep 19..

Manipulating Galectin Expression in Zebrafish (Danio rerio)

Authors:
Feng C, Nita-Lazar M, González-Montalbán N, Wang J, Mancini J, Ravindran C, Ahmed H, Vasta GR
Citation:
Methods Mol Biol. 2015;1207:327-41. doi: 10.1007/978-1-4939-1396-1_22
Epub:
Not Epub
Abstract:
Techniques for disrupting gene expression are invaluable tools for the analysis of the biological role(s) of a gene product....
Organism or Cell Type:
zebrafish
Citation Extract:
Feng C, Nita-Lazar M, González-Montalbán N, Wang J, Mancini J, Ravindran C, Ahmed H, Vasta GR. Manipulating Galectin Expression in Zebrafish (Danio rerio). Methods Mol Biol. 2015;1207:327-41. doi: 10.1007/978-1-4939-1396-1_22.

Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

Authors:
French CR, Seshadri S, Destefano AL, Fornage M, Arnold CR, Gage PJ, Skarie JM, Dobyns WB, Millen KJ, Liu T, Dietz W, Kume T, Hofker M, Emery DJ, Childs SJ, Waskiewicz AJ, Lehmann OJ
Citation:
J Clin Invest. 2014 Sep 24. pii: 75109. doi: 10.1172/JCI75109. [Epub ahead of print]
Epub:
Yes
Abstract:
Patients with cerebral small-vessel disease (CSVD) exhibit perturbed end-artery function and have an increased risk for stroke...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
French CR, Seshadri S, Destefano AL, Fornage M, Arnold CR, Gage PJ, Skarie JM, Dobyns WB, Millen KJ, Liu T, Dietz W, Kume T, Hofker M, Emery DJ, Childs SJ, Waskiewicz AJ, Lehmann OJ. Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease. J Clin Invest. 2014 Sep 24. pii: 75109. doi: 10.1172/JCI75109. [Epub ahead of print].

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