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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development

Authors:
Tu T, Zhang C, Yan H, Luo Y, Kong R, Wen P, Ye Z, Chen J, Feng J, Liu F, Wu JY, Yan X
Citation:
Cell Res. 2015 Feb 6. doi: 10.1038/cr.2015.15. [Epub ahead of print]
Epub:
Yes
Abstract:
Angiogenesis, a process that newly-formed blood vessels sprout from pre-existing ones, is vital for vertebrate development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tu T, Zhang C, Yan H, Luo Y, Kong R, Wen P, Ye Z, Chen J, Feng J, Liu F, Wu JY, Yan X. CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development. Cell Res. 2015 Feb 6. doi: 10.1038/cr.2015.15. [Epub ahead of print].

Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis

Authors:
Liu Y, Wang C, Destin G, Szaro BG
Citation:
Eur J Neurosci. 2015 Feb 6. doi: 10.1111/ejn.12848. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Compared with its roles in neurodegeneration, much less is known about microtubule-associated protein tau's normal...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu Y, Wang C, Destin G, Szaro BG. Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis. Eur J Neurosci. 2015 Feb 6. doi: 10.1111/ejn.12848. [Epub ahead of print].

A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis

Authors:
Ristori E, Lopez-Ramirez MA, Narayanan A, Hill-Teran G, Moro A, Calvo C-F, Thomas J-L, Nicoli S
Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.013
Epub:
Yes
Abstract:
Dicer controls the biogenesis of microRNAs (miRNAs) and is essential for neurogenesis. Recent reports show that the levels and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ristori E, Lopez-Ramirez MA, Narayanan A, Hill-Teran G, Moro A, Calvo C-F, Thomas J-L, Nicoli S. A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.013.

High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides

Authors:
Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL
Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060
Epub:
Yes
Abstract:
The therapeutic use of antisense and siRNA oligonucleotides has been constrained by the limited ability of these membrane-...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: A375 melanoma cells
Citation Extract:
Yang B, Ming X, Cao C, Laing B, Yuan A, Porter MA, Hull-Ryde EA, Maddry J, Suto M, Janzen WP, Juliano RL. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv060 .

PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation

Authors:
Nath AK, Ryu JH, Jin YN, Roberts LD, Dejam A, Gerszten RE, Peterson RT
Citation:
Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010
Epub:
Yes
Abstract:
Virtually all organisms seek to maximize fitness by matching fuel availability with energy expenditure. In vertebrates, glucose...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nath AK, Ryu JH, Jin YN, Roberts LD, Dejam A, Gerszten RE, Peterson RT. PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation. Cell Rep. 2015;[Epub ahead of print] doi:/10.1016/j.celrep.2015.01.010.

cnrip1 is a regulator of eye and neural development in Xenopus laevis

Authors:
Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M
Citation:
Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print]
Epub:
Yes
Abstract:
Cannabinoid receptor interacting protein 1 (CNRIP1), which has been originally identified as the binding partner of cannabinoid...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M. cnrip1 is a regulator of eye and neural development in Xenopus laevis. Genes Cells. 2015 Feb 5. doi: 10.1111/gtc.12225. [Epub ahead of print].

FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway

Authors:
Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R
Citation:
Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588
Epub:
Not Epub
Abstract:
Haematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R. FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588.

Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria

Authors:
Capo-Chichi JM, Boissel S, Brustein E, Pickles S, Fallet-Bianco C, Nassif C, Patry L, Dobrzeniecka S, Liao M, Labuda D, Samuels ME, Hamdan FF, Velde CV, Rouleau GA, Drapeau P, Michaud JL
Citation:
J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The heterogeneous group of 3-methylglutaconic aciduria disorders includes several inborn errors of metabolism that...
Organism or Cell Type:
zebrafish
Citation Extract:
Capo-Chichi JM, Boissel S, Brustein E, Pickles S, Fallet-Bianco C, Nassif C, Patry L, Dobrzeniecka S, Liao M, Labuda D, Samuels ME, Hamdan FF, Velde CV, Rouleau GA, Drapeau P, Michaud JL. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J Med Genet. 2015 Feb 3. pii: jmedgenet-2014-102952. doi: 10.1136/jmedgenet-2014-102952. [Epub ahead of print].

A comparison of two cellular delivery mechanisms for small interfering RNA

Authors:
Valiunas V, Wang HZ, Li L, Gordon C, Valiuniene L, Cohen IS, Brink PR
Citation:
Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1
Epub:
Not Epub
Abstract:
Cellular delivery of small interfering RNAs to target cells of a tissue has the potential to travel by two intercellular...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLaCx43 & HEK293
Citation Extract:
Valiunas V, Wang HZ, Li L, Gordon C, Valiuniene L, Cohen IS, Brink PR. A comparison of two cellular delivery mechanisms for small interfering RNA. Physiol Rep. 2015 Feb 3;3(2). pii: e12286. doi: 10.14814/phy2.12286. Print 2015 Feb 1.

Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis

Authors:
Koganti SR, Zhu Z, Subbotina E, Gao Z, Sierra A, Proenza M, Yang L, Alekseev A, Hodgson-Zingman D, Zingman L
Citation:
Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4.
Epub:
Yes
Abstract:
Despite the medical, social and economic impact of obesity, only a few therapeutic options, focused largely on reducing caloric...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Koganti SR, Zhu Z, Subbotina E, Gao Z, Sierra A, Proenza M, Yang L, Alekseev A, Hodgson-Zingman D, Zingman L. Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis. Mol Ther. 2015 Apr;23(4):707-16. doi: 10.1038/mt.2015.21. Epub 2015 Feb 4..

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