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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain

Authors:
Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N
Citation:
PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014
Epub:
Not Epub
Abstract:
Fibroblast growth factor (Fgf) signaling plays crucial roles in various developmental processes including those in the brain....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N. Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain. PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014.

Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice

Authors:
Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G
Citation:
Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014
Epub:
Not Epub
Abstract:
Although an increasing number of antibody conjugates are being used in the clinic, there remain many unmet needs in antibody...
Delivery Method:
pretargeting
Organism or Cell Type:
mice
Citation Extract:
Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G. Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice. Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014.

Interaction of Infectious Spleen and Kidney Necrosis Virus ORF119L with PINCH Leads to Dominant-Negative Inhibition of ILK and Cardiovascular Defects in Zebrafish

Authors:
Yuan J-M, He B-L, Yang L-Y, Guo C-J, Weng S-P, Li SC, He J-G
Citation:
J Virol. 2014. [Epub ahead of print] doi:10.1128/JVI.01955-14
Epub:
Yes
Abstract:
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus, Iridoviridae family,...
Delivery Method:
injection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan J-M, He B-L, Yang L-Y, Guo C-J, Weng S-P, Li SC, He J-G. Interaction of Infectious Spleen and Kidney Necrosis Virus ORF119L with PINCH Leads to Dominant-Negative Inhibition of ILK and Cardiovascular Defects in Zebrafish. J Virol. 2014. [Epub ahead of print] doi:10.1128/JVI.01955-14.

Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease

Authors:
Clayton NP, Nelson CA, Weeden T, Taylor KM, Moreland RJ, Scheule RK, Phillips L, Leger AJ, Cheng SH, Wentworth BM
Citation:
Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57
Epub:
Not Epub
Abstract:
Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA; EC 3.2.1.20) and the...
Delivery Method:
injection & electroporation or peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Clayton NP, Nelson CA, Weeden T, Taylor KM, Moreland RJ, Scheule RK, Phillips L, Leger AJ, Cheng SH, Wentworth BM. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease. Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57.

FIH-1, a Novel Interactor of Mindbomb, Functions as an Essential Anti-Angiogenic Factor during Zebrafish Vascular Development

Authors:
So J-H, Kim J-D, Yoo K-W, Kim H-T, Jung S-H, Choi J-H, Lee M-S, Jin S-W
Citation:
PLoS ONE. 2014;9(10):e109517. doi:10.1371/journal.pone.0109517
Epub:
Not Epub
Abstract:
Objective: It has been shown that Mindbomb (Mib), an E3 Ubiquitin ligase, is an essential modulator of Notch signaling during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
So J-H, Kim J-D, Yoo K-W, Kim H-T, Jung S-H, Choi J-H, Lee M-S, Jin S-W. FIH-1, a Novel Interactor of Mindbomb, Functions as an Essential Anti-Angiogenic Factor during Zebrafish Vascular Development. PLoS ONE. 2014;9(10):e109517. doi:10.1371/journal.pone.0109517.

FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis

Authors:
Petridou NI, Skourides PA
Citation:
Nat Commun. 2014 Oct 24;5:5240. doi: 10.1038/ncomms6240
Epub:
Not Epub
Abstract:
Spindle orientation is critical for proper morphogenesis of organs and tissues as well as for the maintenance of tissue...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Petridou NI, Skourides PA. FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. Nat Commun. 2014 Oct 24;5:5240. doi: 10.1038/ncomms6240.

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

Authors:
Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Daire VC, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP
Citation:
Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3122. [Epub ahead of print]
Epub:
Yes
Abstract:
Centrioles are essential for ciliogenesis. However, mutations in centriole biogenesis genes have been reported in primary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Daire VC, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3122. [Epub ahead of print].

Deleterious mutations in the essential mRNA metabolism factor, hGle1, in Amyotrophic Lateral Sclerosis

Authors:
Kaneb HM, Folkmann AW, Belzil VV, Jao LE, Leblond CS, Girard SL, Daoud H, Noreau A, Rochefort D, Hince P, Szuto A, Levert A, Vidal S, André-Guimont C, Camu W, Bouchard JP, Dupré N, Rouleau GA, Wente SR, Dion PA
Citation:
Hum Mol Genet. 2014 Oct 24. pii: ddu545. [Epub ahead of print]
Epub:
Yes
Abstract:
ALS is a fatal neurodegenerative disorder characterised by the selective death of motor neurons. Causative mutations in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kaneb HM, Folkmann AW, Belzil VV, Jao LE, Leblond CS, Girard SL, Daoud H, Noreau A, Rochefort D, Hince P, Szuto A, Levert A, Vidal S, André-Guimont C, Camu W, Bouchard JP, Dupré N, Rouleau GA, Wente SR, Dion PA. Deleterious mutations in the essential mRNA metabolism factor, hGle1, in Amyotrophic Lateral Sclerosis. Hum Mol Genet. 2014 Oct 24. pii: ddu545. [Epub ahead of print].

FoxA4 Favours Notochord Formation by Inhibiting Contiguous Mesodermal Fates and Restricts Anterior Neural Development in Xenopus Embryos

Authors:
Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL
Citation:
PLoS ONE. 2014;9(10):e110559. doi:10.1371/journal.pone.0110559
Epub:
Not Epub
Abstract:
In vertebrates, the embryonic dorsal midline is a crucial signalling centre that patterns the surrounding tissues during...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL. FoxA4 Favours Notochord Formation by Inhibiting Contiguous Mesodermal Fates and Restricts Anterior Neural Development in Xenopus Embryos. PLoS ONE. 2014;9(10):e110559. doi:10.1371/journal.pone.0110559.

Lysine-specific demethylase 1 expression in zebrafish during the early stages of neuronal development

Authors:
Li A, Sun Y, Dou C, Chen J, Zhang J
Citation:
Neural Regen Res. 2012 Dec 5;7(34):2719-26. doi: 10.3969/j.issn.1673-5374.2012.34.010
Epub:
Not Epub
Abstract:
Lysine-specific demethylase 1 (Lsd1) is associated with transcriptional coregulation via the modulation of histone methylation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li A, Sun Y, Dou C, Chen J, Zhang J. Lysine-specific demethylase 1 expression in zebrafish during the early stages of neuronal development. Neural Regen Res. 2012 Dec 5;7(34):2719-26. doi: 10.3969/j.issn.1673-5374.2012.34.010.

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