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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Proinflammatory Signaling Regulates Hematopoietic Stem Cell Emergence

Authors:
Espín-Palazón R, Stachura DL, Campbell CA, García-Moreno D, Del Cid N, Kim AD, Candel S, Meseguer J, Mulero V, Traver D
Citation:
Cell. 2014;[Epub ahead of print] doi:10.1016/j.cell.2014.10.031
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) underlie the production of blood and immune cells for the lifetime of an organism. In...
Link:
http://www.sciencedirect.com/science/article/pii/S0092867414013191
Delivery Method:
microinjection
Citation Extract:
Espín-Palazón R, Stachura DL, Campbell CA, García-Moreno D, Del Cid N, Kim AD, Candel S, Meseguer J, Mulero V, Traver D. Proinflammatory Signaling Regulates Hematopoietic Stem Cell Emergence. Cell. 2014;[Epub ahead of print] doi:10.1016/j.cell.2014.10.031.

Dosage Changes of a Segment at 17p13.1 Lead to Intellectual Disability and Microcephaly as a Result of Complex Genetic Interaction of Multiple Genes

Authors:
Carvalho CMB, Vasanth S, Shinawi M, Russell C, Ramocki MB, Brown CW, Graakjaer J, Skytte A-B, Vianna-Morgante AM, Krepischi ACV, Patel GS, Immken L, Aleck K, Lim C, Cheung SW, Rosenberg C, Katsanis N, Lupskiemail JR
Citation:
Am J Hum Genet. 2014;95(5):565-78. doi:/10.1016/j.ajhg.2014.10.006
Epub:
Not Epub
Abstract:
The 17p13.1 microdeletion syndrome is a recently described genomic disorder with a core clinical phenotype of intellectual...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(14)00428-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carvalho CMB, Vasanth S, Shinawi M, Russell C, Ramocki MB, Brown CW, Graakjaer J, Skytte A-B, Vianna-Morgante AM, Krepischi ACV, Patel GS, Immken L, Aleck K, Lim C, Cheung SW, Rosenberg C, Katsanis N, Lupskiemail JR. Dosage Changes of a Segment at 17p13.1 Lead to Intellectual Disability and Microcephaly as a Result of Complex Genetic Interaction of Multiple Genes. Am J Hum Genet. 2014;95(5):565-78. doi:/10.1016/j.ajhg.2014.10.006.

Novel Matrix Proteins of Pteria penguin Pearl Oyster Shell Nacre Homologous to the Jacalin-Related β-Prism Fold Lectins

Authors:
Naganuma T, Hoshino W, Shikanai Y, Sato R, Liu K, Sato S, Muramoto K, Osada M, Yoshima K, Ogawa T
Citation:
PLoS ONE. 2014;9(11):e112326. doi:10.1371/journal.pone.0112326
Epub:
Not Epub
Abstract:
Nacreous layers of pearl oyster are one of the major functional biominerals. By participating in organic compound-crystal...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0112326
Delivery Method:
Endo-Porter
Organism or Cell Type:
Pteria penguin (oyster)
Citation Extract:
Naganuma T, Hoshino W, Shikanai Y, Sato R, Liu K, Sato S, Muramoto K, Osada M, Yoshima K, Ogawa T. Novel Matrix Proteins of Pteria penguin Pearl Oyster Shell Nacre Homologous to the Jacalin-Related β-Prism Fold Lectins. PLoS ONE. 2014;9(11):e112326. doi:10.1371/journal.pone.0112326.

Two-pore channels function in calcium regulation in sea star oocytes and embryos

Authors:
Ramos I, Reich A, Wessel GM
Citation:
Development. 2014;[Epub ahead of print] doi:10.1242/dev.113563
Epub:
Not Epub
Abstract:
Egg activation at fertilization is an excellent process for studying calcium regulation. Nicotinic acid adenine dinucleotide-...
Link:
http://dev.biologists.org/content/early/2014/11/05/dev.113563.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Ramos I, Reich A, Wessel GM. Two-pore channels function in calcium regulation in sea star oocytes and embryos. Development. 2014;[Epub ahead of print] doi:10.1242/dev.113563.

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity

Authors:
Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R
Citation:
Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28
Epub:
Not Epub
Abstract:
Immunoglobulin light chain (LC) amyloidosis (AL) results from overproduction of circulating amyloidogenic LC proteins and...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914405/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R. Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity. Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28.

Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c

Authors:
Toyama R, Kim MH, Rebbert ML, Gonzales J, Burgess H, Dawid IB
Citation:
Dev Dyn. 2013 Sep;242(9):1033-42. doi: 10.1002/dvdy.23994. Epub 2013 Jun 27
Epub:
Not Epub
Abstract:
Background: The zebrafish pineal gland (epiphysis) is a site of melatonin production, contains photoreceptor cells, and...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757502/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toyama R, Kim MH, Rebbert ML, Gonzales J, Burgess H, Dawid IB. Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c. Dev Dyn. 2013 Sep;242(9):1033-42. doi: 10.1002/dvdy.23994. Epub 2013 Jun 27.

Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development

Authors:
Lin CJ, Conti M, Ramalho-Santos M
Citation:
Development. 2013 Sep;140(17):3624-34. doi: 10.1242/dev.095513. Epub 2013 Jul 31
Epub:
Not Epub
Abstract:
Histone variants can replace canonical histones in the nucleosome and modify chromatin structure and gene expression. The...
Link:
http://dev.biologists.org/content/140/17/3624.long
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Lin CJ, Conti M, Ramalho-Santos M. Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development. Development. 2013 Sep;140(17):3624-34. doi: 10.1242/dev.095513. Epub 2013 Jul 31.

A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates

Authors:
Bessa J, Luengo M, Rivero-Gil S, Ariza-Cosano A, Maia AH, Ruiz-Ruano FJ, Caballero P, Naranjo S, Carvajal JJ, Gómez-Skarmeta JL
Citation:
Genome Res. 2014 Mar;24(3):487-95. doi: 10.1101/gr.165654.113. Epub 2013 Nov 25
Epub:
Not Epub
Abstract:
In multicellular organisms, cis-regulation controls gene expression in space and time. Despite the essential implication of cis...
Link:
http://genome.cshlp.org/content/24/3/487.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bessa J, Luengo M, Rivero-Gil S, Ariza-Cosano A, Maia AH, Ruiz-Ruano FJ, Caballero P, Naranjo S, Carvajal JJ, Gómez-Skarmeta JL. A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates. Genome Res. 2014 Mar;24(3):487-95. doi: 10.1101/gr.165654.113. Epub 2013 Nov 25.

Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata

Authors:
Lee J, Lee BK, Gross JM
Citation:
Hum Mol Genet. 2013 Sep 1;22(17):3568-82. doi: 10.1093/hmg/ddt211. Epub 2013 May 12
Epub:
Not Epub
Abstract:
Mutations in BCOR (Bcl6 corepressor) are found in patients with oculo-facio-cardio-dental (OFCD) syndrome, a congenital...
Link:
http://hmg.oxfordjournals.org/content/22/17/3568.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Lee BK, Gross JM. Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata. Hum Mol Genet. 2013 Sep 1;22(17):3568-82. doi: 10.1093/hmg/ddt211. Epub 2013 May 12.

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites

Authors:
Kim Y-J, Bahn M, Kim YH, Shin J-Y, Cheong S-W, Ju B-G, Kim W-S, Yeo C-Y
Citation:
Dev Biol. 2014 Nov 4. pii: S0012-1606(14)00560-0. doi: 10.1016/j.ydbio.2014.10.019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Members of the fibroblast growth factor (FGF) family play important roles during various developmental processes including eye...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614005600
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim Y-J, Bahn M, Kim YH, Shin J-Y, Cheong S-W, Ju B-G, Kim W-S, Yeo C-Y. Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites. Dev Biol. 2014 Nov 4. pii: S0012-1606(14)00560-0. doi: 10.1016/j.ydbio.2014.10.019. [Epub ahead of print].

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