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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

AHR2-mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs

Authors:
Jayasundara N, Van Tiem Garner L, Meyer JN, Erwin K, Di Giulio RT
Citation:
Toxicol Sci. 2014 Nov 19. pii: kfu245. [Epub ahead of print]
Epub:
Yes
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) induce developmental defects including cardiac deformities in fish. The aryl...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jayasundara N, Van Tiem Garner L, Meyer JN, Erwin K, Di Giulio RT. AHR2-mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs. Toxicol Sci. 2014 Nov 19. pii: kfu245. [Epub ahead of print].

Molecular cloning and functional characterization of chicken Atonal homologue 1: a comparison with human Atoh1

Authors:
Mulvaney JF, Amemiya Y, Freeman SD, Ladher RK, Dabdoub A
Citation:
Biol Cell. 2014 Nov 21. doi: 10.1111/boc.201400078. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND INFORMATION: The vertebrate basic helix-loop-helix transcription factor Atoh1 is essential for maturation and...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Mulvaney JF, Amemiya Y, Freeman SD, Ladher RK, Dabdoub A. Molecular cloning and functional characterization of chicken Atonal homologue 1: a comparison with human Atoh1. Biol Cell. 2014 Nov 21. doi: 10.1111/boc.201400078. [Epub ahead of print].

Protocadherin-9 involvement in retinal development in Xenopus laevis

Authors:
Izuta Y, Taira T, Asayama A, Machigashira M, Kinoshita T, Fujiwara M, Suzuki ST
Citation:
J Biochem. 2014;[Epub ahead of print] doi:10.1093/jb/mvu070
Epub:
Yes
Abstract:
Biological roles of most protocadherins are a largely unsolved problem. Therefore, we cloned cDNA for Xenopus laevis...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Izuta Y, Taira T, Asayama A, Machigashira M, Kinoshita T, Fujiwara M, Suzuki ST. Protocadherin-9 involvement in retinal development in Xenopus laevis. J Biochem. 2014;[Epub ahead of print] doi:10.1093/jb/mvu070 .

Parallel Synthesis of Cell-Penetrating Peptide Conjugates of PMO Toward Exon Skipping Enhancement in Duchenne Muscular Dystrophy

Authors:
O'Donovan L, Okamoto I, Arzumanov AA, Williams DL, Deuss P, Gait MJ
Citation:
Nucleic Acid Ther. 2014 Nov 20. [Epub ahead of print]
Epub:
Yes
Abstract:
We describe two new methods of parallel chemical synthesis of libraries of peptide conjugates of phosphorodiamidate morpholino...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: murine H2k mdx myoblast
Citation Extract:
O'Donovan L, Okamoto I, Arzumanov AA, Williams DL, Deuss P, Gait MJ. Parallel Synthesis of Cell-Penetrating Peptide Conjugates of PMO Toward Exon Skipping Enhancement in Duchenne Muscular Dystrophy. Nucleic Acid Ther. 2014 Nov 20. [Epub ahead of print].

Live Imaging and Gene Expression Analysis in Zebrafish Identifies a Link between Neutrophils and Epithelial to Mesenchymal Transition

Authors:
Freisinger CM, Huttenlocher A
Citation:
PLoS One. 2014 Nov 5;9(11):e112183. doi: 10.1371/journal.pone.0112183. eCollection 2014
Epub:
Not Epub
Abstract:
Chronic inflammation is associated with epithelial to mesenchymal transition (EMT) and cancer progression however the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Freisinger CM, Huttenlocher A. Live Imaging and Gene Expression Analysis in Zebrafish Identifies a Link between Neutrophils and Epithelial to Mesenchymal Transition. PLoS One. 2014 Nov 5;9(11):e112183. doi: 10.1371/journal.pone.0112183. eCollection 2014.

Wild-type mouse models to screen antisense oligonucleotides for exon-skipping efficacy in duchenne muscular dystrophy

Authors:
Cao L, Han G, Gu B, Yin H
Citation:
PLoS One. 2014 Nov 3;9(11):e111079. doi: 10.1371/journal.pone.0111079. eCollection 2014
Epub:
Not Epub
Abstract:
A readily available animal model is essential for rapidly identifying effective treatments for Duchenne muscular dystrophy (DMD...
Delivery Method:
injection and peptide-coupled
Organism or Cell Type:
mice
Citation Extract:
Cao L, Han G, Gu B, Yin H. Wild-type mouse models to screen antisense oligonucleotides for exon-skipping efficacy in duchenne muscular dystrophy. PLoS One. 2014 Nov 3;9(11):e111079. doi: 10.1371/journal.pone.0111079. eCollection 2014.

miR-210 inhibits trophoblast invasion and is a serum biomarker for preeclampsia

Authors:
Anton L, Olarerin-George AO, Schwartz N, Srinivas S, Bastek J, Hogenesch JB, Elovitz MA
Citation:
Am J Pathol. 2013 Nov;183(5):1437-45. doi: 10.1016/j.ajpath.2013.07.021. Epub 2013 Sep 10
Epub:
Not Epub
Abstract:
Preeclampsia is characterized by hypertension and proteinuria in pregnant women. Its exact cause is unknown. Preeclampsia...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human extravillous trophoblast
Citation Extract:
Anton L, Olarerin-George AO, Schwartz N, Srinivas S, Bastek J, Hogenesch JB, Elovitz MA. miR-210 inhibits trophoblast invasion and is a serum biomarker for preeclampsia. Am J Pathol. 2013 Nov;183(5):1437-45. doi: 10.1016/j.ajpath.2013.07.021. Epub 2013 Sep 10.

Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity

Authors:
Warga RM, Mueller RL, Ho RK, Kane DA
Citation:
Dev Biol. 2013 Nov 1;383(1):75-89. doi: 10.1016/j.ydbio.2013.08.018. Epub 2013 Sep 2
Epub:
Not Epub
Abstract:
Progenitors of the zebrafish pronephros, red blood and trunk endothelium all originate from the ventral mesoderm and often...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Warga RM, Mueller RL, Ho RK, Kane DA. Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity. Dev Biol. 2013 Nov 1;383(1):75-89. doi: 10.1016/j.ydbio.2013.08.018. Epub 2013 Sep 2.

Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression

Authors:
Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce A, Wardle FC
Citation:
BMC Biol. 2014 Oct 3;12(1):81. doi: 10.1186/s12915-014-0081-5
Epub:
Not Epub
Abstract:
Background: Nodal signalling is an absolute requirement for normal mesoderm and endoderm formation in vertebrate embryos, yet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce A, Wardle FC. Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression. BMC Biol. 2014 Oct 3;12(1):81. doi: 10.1186/s12915-014-0081-5.

Sp8 regulates inner ear development

Authors:
Chung HA, Medina-Ruiz S, Harland RM
Citation:
Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6329-34. doi: 10.1073/pnas.1319301111. Epub 2014 Apr 10
Epub:
Not Epub
Abstract:
A forward genetic screen of N-ethyl-N-nitrosourea mutagenized Xenopus tropicalis has identified an inner ear mutant named...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Chung HA, Medina-Ruiz S, Harland RM. Sp8 regulates inner ear development. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6329-34. doi: 10.1073/pnas.1319301111. Epub 2014 Apr 10.

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