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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice

Authors:
Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T
Citation:
Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76
Epub:
Not Epub
Abstract:
Antisense-mediated exon skipping, which can restore the reading frame, is a most promising therapeutic approach for Duchenne...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mdx52 mice
Citation Extract:
Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T. Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45-55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice. Mol Ther Nucleic Acids. 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76.

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms

Authors:
Love NR, Pollak N, Dölle C, Niere M, Chen Y, Oliveri P, Amaya E, Patel S, Ziegler M
Citation:
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print]
Epub:
Yes
Abstract:
Nicotinamide adenine dinucleotide phosphate (NADP) is a critical cofactor during metabolism, calcium signaling, and oxidative...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Love NR, Pollak N, Dölle C, Niere M, Chen Y, Oliveri P, Amaya E, Patel S, Ziegler M. NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201417290. [Epub ahead of print].

Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics

Authors:
Tsuruwaka Y, Konishi M, Shimada E
Citation:
PeerJ. 2015;3:e727 doi:10.7717/peerj.727
Epub:
Not Epub
Abstract:
We investigated the role of the WW domain-containing oxidoreductase (wwox) gene in the embryonic development of zebrafish, with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsuruwaka Y, Konishi M, Shimada E. Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics. PeerJ. 2015;3:e727 doi:10.7717/peerj.727.

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

Authors:
Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201424576. [Epub ahead of print]
Epub:
Yes
Abstract:
Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201424576. [Epub ahead of print].

Functional variants of POC5 identified in patients with idiopathic scoliosis

Authors:
Patten SA, Margaritte-Jeannin P, Bernard JC, Alix E, Labalme A, Besson A, Girard SL, Fendri K, Fraisse N, Biot B, Poizat C, Campan-Fournier A, Abelin-Genevois K, Cunin V, Zaouter C, Liao M, Lamy R, Lesca G, Menassa R, Marcaillou C, Letexier M, Sanlaville D, Berard J, Rouleau GA, Clerget-Darpoux F, Drapeau P, Moldovan F, Edery P
Citation:
J Clin Invest. 2015 Feb 2. pii: 77262. doi: 10.1172/JCI77262. [Epub ahead of print]
Epub:
Yes
Abstract:
Idiopathic scoliosis (IS) is a spine deformity that affects approximately 3% of the population. The underlying causes of IS are...
Organism or Cell Type:
zebrafish
Citation Extract:
Patten SA, Margaritte-Jeannin P, Bernard JC, Alix E, Labalme A, Besson A, Girard SL, Fendri K, Fraisse N, Biot B, Poizat C, Campan-Fournier A, Abelin-Genevois K, Cunin V, Zaouter C, Liao M, Lamy R, Lesca G, Menassa R, Marcaillou C, Letexier M, Sanlaville D, Berard J, Rouleau GA, Clerget-Darpoux F, Drapeau P, Moldovan F, Edery P. Functional variants of POC5 identified in patients with idiopathic scoliosis. J Clin Invest. 2015 Feb 2. pii: 77262. doi: 10.1172/JCI77262. [Epub ahead of print].

Interception of host angiogenic signalling limits mycobacterial growth

Authors:
Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM
Citation:
Nature. 2015 Jan 29;517(7536):612-5. doi: 10.1038/nature13967. Epub 2014 Nov 24
Epub:
Not Epub
Abstract:
Pathogenic mycobacteria induce the formation of complex cellular aggregates called granulomas that are the hallmark of...
Organism or Cell Type:
zebrafish
Citation Extract:
Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM. Interception of host angiogenic signalling limits mycobacterial growth. Nature. 2015 Jan 29;517(7536):612-5. doi: 10.1038/nature13967. Epub 2014 Nov 24.

Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins

Authors:
Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupé S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S
Citation:
Dev Cell. 2015 Jan 26;32(2):181-90. doi: 10.1016/j.devcel.2014.12.016
Epub:
Not Epub
Abstract:
Mechanotransduction pathways are activated in response to biophysical stimuli during the development or homeostasis of organs...
Organism or Cell Type:
zebrafish
Citation Extract:
Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupé S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S. Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Dev Cell. 2015 Jan 26;32(2):181-90. doi: 10.1016/j.devcel.2014.12.016.

The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression

Authors:
Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML
Citation:
Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009
Epub:
Not Epub
Abstract:
The cerebral cavernous malformation (CCM) pathway is required in endothelial cells for normal cardiovascular development and to...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression. Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009.

Detection of sequence-specific DNA with morpholino-functionalized silicon chip

Authors:
Hu W, Hu Q, Li L, Kong J, Zhang X
Citation:
Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C4AY02780A
Epub:
Yes
Abstract:
In this work, an efficient method for the sequence-specific detection of DNA based on a morpholino-functionalized silicon chip...
Citation Extract:
Hu W, Hu Q, Li L, Kong J, Zhang X. Detection of sequence-specific DNA with morpholino-functionalized silicon chip. Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C4AY02780A.

Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State

Authors:
Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N
Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.024
Epub:
Yes
Abstract:
Hox transcription factors (TFs) are essential for vertebrate development, but how these evolutionary conserved proteins...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N. Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.024.

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