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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12175 scientific papers returned from the database with the search filters currently being used below.

FoxA4 Favours Notochord Formation by Inhibiting Contiguous Mesodermal Fates and Restricts Anterior Neural Development in Xenopus Embryos

Authors:
Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL
Citation:
PLoS ONE. 2014;9(10):e110559. doi:10.1371/journal.pone.0110559
Epub:
Not Epub
Abstract:
In vertebrates, the embryonic dorsal midline is a crucial signalling centre that patterns the surrounding tissues during...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL. FoxA4 Favours Notochord Formation by Inhibiting Contiguous Mesodermal Fates and Restricts Anterior Neural Development in Xenopus Embryos. PLoS ONE. 2014;9(10):e110559. doi:10.1371/journal.pone.0110559.

Lysine-specific demethylase 1 expression in zebrafish during the early stages of neuronal development

Authors:
Li A, Sun Y, Dou C, Chen J, Zhang J
Citation:
Neural Regen Res. 2012 Dec 5;7(34):2719-26. doi: 10.3969/j.issn.1673-5374.2012.34.010
Epub:
Not Epub
Abstract:
Lysine-specific demethylase 1 (Lsd1) is associated with transcriptional coregulation via the modulation of histone methylation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li A, Sun Y, Dou C, Chen J, Zhang J. Lysine-specific demethylase 1 expression in zebrafish during the early stages of neuronal development. Neural Regen Res. 2012 Dec 5;7(34):2719-26. doi: 10.3969/j.issn.1673-5374.2012.34.010.

Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development

Authors:
Le Pabic P, Ng C, Schilling TF
Citation:
PLoS Genet. 2014;10(10):e1004726. doi:10.1371/journal.pgen.1004726
Epub:
Not Epub
Abstract:
Organogenesis requires coordinated regulation of cellular differentiation and morphogenesis. Cartilage cells in the vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le Pabic P, Ng C, Schilling TF. Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development. PLoS Genet. 2014;10(10):e1004726. doi:10.1371/journal.pgen.1004726.

Nephronophthisis-Associated CEP164 Regulates Cell Cycle Progression, Apoptosis and Epithelial-to-Mesenchymal Transition

Authors:
Slaats GG, Ghosh AK, Falke LL, Le Corre S, Shaltiel IA, van de Hoek G Klasson TD, Stokman MF, Logister I, Verhaar MC, Goldschmeding R, Nguyen TQ, Drummond IA, Hildebrandt F, Giles RH
Citation:
PLoS Genet. 2014;10(10):e1004594. doi:10.1371/journal.pgen.1004594
Epub:
Not Epub
Abstract:
We recently reported that centrosomal protein 164 (CEP164) regulates both cilia and the DNA damage response in the autosomal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Slaats GG, Ghosh AK, Falke LL, Le Corre S, Shaltiel IA, van de Hoek G Klasson TD, Stokman MF, Logister I, Verhaar MC, Goldschmeding R, Nguyen TQ, Drummond IA, Hildebrandt F, Giles RH. Nephronophthisis-Associated CEP164 Regulates Cell Cycle Progression, Apoptosis and Epithelial-to-Mesenchymal Transition. PLoS Genet. 2014;10(10):e1004594. doi:10.1371/journal.pgen.1004594.

Interferon Regulatory Factor-1 (IRF-1) Is Involved in the Induction of Phosphatidylserine Receptor (PSR) in Response to dsRNA Virus Infection and Contributes to Apoptotic Cell Clearance in CHSE-214 Cell

Authors:
Kung H-C, Evensen Ø, Hong J-R, Kuo C-Y, Tso C-H, Ngou F-H, Lu M-W, Wu J-L
Citation:
Int. J. Mol. Sci. 2014;15(10):19281-19306. doi:10.3390/ijms151019281
Epub:
Not Epub
Abstract:
The phosphatidylserine receptor (PSR) recognizes a surface marker on apoptotic cells and initiates engulfment. This receptor is...
Delivery Method:
electroporation, Endo-Porter
Organism or Cell Type:
cell culture: CHSE-214 (salmon)
Citation Extract:
Kung H-C, Evensen Ø, Hong J-R, Kuo C-Y, Tso C-H, Ngou F-H, Lu M-W, Wu J-L. Interferon Regulatory Factor-1 (IRF-1) Is Involved in the Induction of Phosphatidylserine Receptor (PSR) in Response to dsRNA Virus Infection and Contributes to Apoptotic Cell Clearance in CHSE-214 Cell. Int. J. Mol. Sci. 2014;15(10):19281-19306. doi:10.3390/ijms151019281.

Roles of retinoic acid and Tbx1/10 in pharyngeal segmentation: amphioxus and the ancestral chordate condition

Authors:
Koop D, Chen J, Theodosiou M, Carvalho JE, Alvarez S, de Lera AR, Holland LZ, Schubert M
Citation:
Evodevo. 2014 Oct 9;5(1):36. doi: 10.1186/2041-9139-5-36. eCollection 2014.
Epub:
Not Epub
Abstract:
Background: Although chordates descend from a segmented ancestor, the evolution of head segmentation has been very...
Delivery Method:
microinjection
Organism or Cell Type:
Florida amphioxus (Branchiostoma floridae)
Citation Extract:
Koop D, Chen J, Theodosiou M, Carvalho JE, Alvarez S, de Lera AR, Holland LZ, Schubert M. Roles of retinoic acid and Tbx1/10 in pharyngeal segmentation: amphioxus and the ancestral chordate condition. Evodevo. 2014 Oct 9;5(1):36. doi: 10.1186/2041-9139-5-36. eCollection 2014..

Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells

Authors:
Conner C, Ackerman KM, Lahne M, Hobgood JS, Hyde DR
Citation:
J Neurosci. 2014;34(43):14403-14419. doi:10.1523/JNEUROSCI.0498-14.2014
Epub:
Not Epub
Abstract:
Retinal damage in teleosts, unlike mammals, induces robust Müller glia-mediated regeneration of lost neurons. We examined...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Conner C, Ackerman KM, Lahne M, Hobgood JS, Hyde DR. Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells. J Neurosci. 2014;34(43):14403-14419. doi:10.1523/JNEUROSCI.0498-14.2014.

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

Authors:
Sugathan A, Biagioli M, Golzio C, Erdin S, Blumenthal I, Manavalan P, Ragavendran A, Brand H, Lucente D, Miles J, Sheridan SD, Stortchevoi A, Kellis M, Haggarty SJ, Katsanis N, Gusella JF, Talkowski ME
Citation:
PNAS. 2014;111(42):E4468-E4477. published ahead of print October 7, 2014, doi:10.1073/pnas.1405266111
Epub:
Yes
Abstract:
Truncating mutations of chromodomain helicase DNA-binding protein 8 (CHD8), and of many other genes with diverse functions, are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sugathan A, Biagioli M, Golzio C, Erdin S, Blumenthal I, Manavalan P, Ragavendran A, Brand H, Lucente D, Miles J, Sheridan SD, Stortchevoi A, Kellis M, Haggarty SJ, Katsanis N, Gusella JF, Talkowski ME. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors. PNAS. 2014;111(42):E4468-E4477. published ahead of print October 7, 2014, doi:10.1073/pnas.1405266111.

Whole-exome Sequencing Identifies a Variant in TMEM132E Causing Autosomal-Recessive Nonsyndromic Hearing Loss DFNB99

Authors:
Li J, Zhao X, Xin Q, Shan S, Jiang B, Jin Y, Yuan H, Dai P, Xiao R, Zhang Q, Xiao J, Shao C, Gong Y, Liu Q
Citation:
Hum Mutat. 2014 Oct 21. doi: 10.1002/humu.22712. [Epub ahead of print]
Epub:
Yes
Abstract:
Autosomal recessive non-syndromic hearing loss (ARNSHL) features a high degree of genetic heterogeneity. Many genes responsible...
Organism or Cell Type:
zebrafish, Xenopus
Citation Extract:
Li J, Zhao X, Xin Q, Shan S, Jiang B, Jin Y, Yuan H, Dai P, Xiao R, Zhang Q, Xiao J, Shao C, Gong Y, Liu Q. Whole-exome Sequencing Identifies a Variant in TMEM132E Causing Autosomal-Recessive Nonsyndromic Hearing Loss DFNB99. Hum Mutat. 2014 Oct 21. doi: 10.1002/humu.22712. [Epub ahead of print].

Orphan G-Protein Coupled Receptor 22 (Gpr22) Regulates Cilia Length and Structure in the Zebrafish Kupffer’s Vesicle

Authors:
Verleyen D, Luyten FP, Tylzanowski P
Citation:
PLoS ONE. 2014;9(10):e110484. doi:10.1371/journal.pone.0110484
Epub:
Not Epub
Abstract:
GPR22 is an orphan G protein-coupled receptor (GPCR). Since the ligand of the receptor is currently unknown, its biological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Verleyen D, Luyten FP, Tylzanowski P. Orphan G-Protein Coupled Receptor 22 (Gpr22) Regulates Cilia Length and Structure in the Zebrafish Kupffer’s Vesicle. PLoS ONE. 2014;9(10):e110484. doi:10.1371/journal.pone.0110484.

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