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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12175 scientific papers returned from the database with the search filters currently being used below.

Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model

Authors:
Elks PM, van der Vaart M, van Hensbergen V, Schutz E, Redd MJ, Murayama E, Spaink HP, Meijer AH
Citation:
PLoS One. 2014 Jun 26;9(6):e100928. doi: 10.1371/journal.pone.0100928. eCollection 2014
Epub:
Not Epub
Abstract:
Pulmonary tuberculosis (TB), caused by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb), is a major world...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elks PM, van der Vaart M, van Hensbergen V, Schutz E, Redd MJ, Murayama E, Spaink HP, Meijer AH. Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model. PLoS One. 2014 Jun 26;9(6):e100928. doi: 10.1371/journal.pone.0100928. eCollection 2014.

Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1

Authors:
Cook K, Clarke P, Warri A, Clarke R
Citation:
Cancer Metab. 2014;2(Suppl 1):P16. doi:10.1186/2049-3002-2-S1-P16
Epub:
Not Epub
Abstract:
Of the 230,000 new cases of invasive breast cancer diagnosed annually, 70% express the estrogen receptor-α and may be treated...
Organism or Cell Type:
cell culture, tumors: LCC1 cells
Citation Extract:
Cook K, Clarke P, Warri A, Clarke R. Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1. Cancer Metab. 2014;2(Suppl 1):P16. doi:10.1186/2049-3002-2-S1-P16.

A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain

Authors:
Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA, Knight R
Citation:
Development. 2014 Jan;141(1):63-72. doi: 10.1242/dev.099507. Epub 2013 Nov 27
Epub:
Not Epub
Abstract:
FGFs and Wnts are important morphogens during midbrain development, but their importance and potential interactions during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA, Knight R. A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain. Development. 2014 Jan;141(1):63-72. doi: 10.1242/dev.099507. Epub 2013 Nov 27.

Laminin β1a controls distinct steps during the establishment of digestive organ laterality

Authors:
Hochgreb-Hägele T, Yin C, Koo DE, Bronner ME, Stainier DY
Citation:
Development. 2013 Jul;140(13):2734-45. doi: 10.1242/dev.097618
Epub:
Not Epub
Abstract:
Visceral organs, including the liver and pancreas, adopt asymmetric positions to ensure proper function. Yet the molecular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hochgreb-Hägele T, Yin C, Koo DE, Bronner ME, Stainier DY. Laminin β1a controls distinct steps during the establishment of digestive organ laterality. Development. 2013 Jul;140(13):2734-45. doi: 10.1242/dev.097618.

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling

Authors:
Iwasaki Y, Thomsen GH
Citation:
Development. 2014;[Epub ahead of print] doi:10.1242/dev.106658
Epub:
Yes
Abstract:
Alternative splicing of pre-mRNAs is an important means of regulating developmental processes, yet the molecular mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Iwasaki Y, Thomsen GH. The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling. Development. 2014;[Epub ahead of print] doi:10.1242/dev.106658.

Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions

Authors:
Mazon Moya MJ, Colucci-Guyon E, Mostowy S
Citation:
JoVE. 2014;(91):e51601. doi:10.3791/51601
Epub:
Not Epub
Abstract:
Shigella flexneri is an intracellular pathogen that can escape from phagosomes to reach the cytosol, and polymerize the host...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazon Moya MJ, Colucci-Guyon E, Mostowy S. Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions. JoVE. 2014;(91):e51601. doi:10.3791/51601.

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

Authors:
Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, Schuetz JD, Malicki J, Zhong TP
Citation:
Nat Cell Biol. 2014 Sep;16(9):841-51. doi: 10.1038/ncb3029. Epub 2014 Aug 31
Epub:
Not Epub
Abstract:
Cilia are microtubule-based organelles that mediate signal transduction in a variety of tissues. Despite their importance, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, Schuetz JD, Malicki J, Zhong TP. Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nat Cell Biol. 2014 Sep;16(9):841-51. doi: 10.1038/ncb3029. Epub 2014 Aug 31.

Disruption of ldlr causes increased LDL-cholesterol and vascular lipid accumulation in a zebrafish model of hypercholesterolemia

Authors:
O'Hare EA, Wang X, Montasser ME, Chang YP, Mitchell BD, Zaghloul NA
Citation:
J Lipid Res. 2014 Sep 8. pii: jlr.M046540. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O'Hare EA, Wang X, Montasser ME, Chang YP, Mitchell BD, Zaghloul NA. Disruption of ldlr causes increased LDL-cholesterol and vascular lipid accumulation in a zebrafish model of hypercholesterolemia. J Lipid Res. 2014 Sep 8. pii: jlr.M046540. [Epub ahead of print].

Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment

Authors:
Bonello-Palot N, Simoncini S, Robert S, Bourgeois P, Sabatier F, Levy N, Dignat-George F, Badens C
Citation:
Atherosclerosis. 2014 Aug 28;237(1):45-52. doi: 10.1016/j.atherosclerosis.2014.08.036. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Defects in lamin A maturation result in premature aging syndromes and severe atherosclerosis as observed in the...
Organism or Cell Type:
cell culture: human primary endothelial cells
Citation Extract:
Bonello-Palot N, Simoncini S, Robert S, Bourgeois P, Sabatier F, Levy N, Dignat-George F, Badens C. Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment. Atherosclerosis. 2014 Aug 28;237(1):45-52. doi: 10.1016/j.atherosclerosis.2014.08.036. [Epub ahead of print].

Characterization of zebrafish pax1b and pax9 in fin bud development

Authors:
Chen X, Huang H, Wang H, Guo F, Du X, Ma L, Zhao L, Pan Z, Gui H, Yuan T, Liu X, Song L, Wang Y, He J, Lei H, Gao R
Citation:
Biomed Res Int. 2014;2014:309385. doi: 10.1155/2014/309385. Epub 2014 Aug 13
Epub:
Not Epub
Abstract:
Both Pax1 and Pax9 belong to the important paired box gene family (PAX), which mainly participates in animal development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Huang H, Wang H, Guo F, Du X, Ma L, Zhao L, Pan Z, Gui H, Yuan T, Liu X, Song L, Wang Y, He J, Lei H, Gao R. Characterization of zebrafish pax1b and pax9 in fin bud development. Biomed Res Int. 2014;2014:309385. doi: 10.1155/2014/309385. Epub 2014 Aug 13.

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