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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification

Authors:
Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M
Citation:
Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322
Epub:
Not Epub
Abstract:
Head specification by the head-selector gene, orthodenticle (otx), is highly conserved among bilaterian lineages. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification. Nat Commun. 2014 Jul 9;5:4322. doi: 10.1038/ncomms5322.

Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy

Authors:
Roosing S, Lamers IJC, de Vrieze E, van den Born LI, Lambertus S, Arts HH, POC1B Study Group, Peters TA, Hoyng CB, Kremer H, Hetterschijt L, Letteboer SJF, van Wijk E, Roepman R, den Hollander AI, Cremers FPM
Citation:
Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012
Epub:
Not Epub
Abstract:
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roosing S, Lamers IJC, de Vrieze E, van den Born LI, Lambertus S, Arts HH, POC1B Study Group, Peters TA, Hoyng CB, Kremer H, Hetterschijt L, Letteboer SJF, van Wijk E, Roepman R, den Hollander AI, Cremers FPM. Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy. Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.06.012.

A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis

Authors:
Bielczyk-Maczyńska E, Serbanovic-Canic J, Ferreira L, Soranzo N, Stemple DL, Ouwehand WH, Cvejic A
Citation:
PLoS Genet. 2014;10(7):e1004450. doi:10.1371/journal.pgen.1004450
Epub:
Not Epub
Abstract:
The formation of mature cells by blood stem cells is very well understood at the cellular level and we know many of the key...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bielczyk-Maczyńska E, Serbanovic-Canic J, Ferreira L, Soranzo N, Stemple DL, Ouwehand WH, Cvejic A. A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis. PLoS Genet. 2014;10(7):e1004450. doi:10.1371/journal.pgen.1004450.

Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis

Authors:
Pillai-Kastoori L, Wen W, Wilson SG, Strachan E, Lo-Castro A, Fichera M, Musumeci SA, Lehmann OJ, Morris AC
Citation:
PLoS Genet. 2014;10(7):e1004491. doi:10.1371/journal.pgen.1004491
Epub:
Not Epub
Abstract:
Ocular coloboma is a sight-threatening malformation caused by failure of the choroid fissure to close during morphogenesis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pillai-Kastoori L, Wen W, Wilson SG, Strachan E, Lo-Castro A, Fichera M, Musumeci SA, Lehmann OJ, Morris AC. Sox11 Is Required to Maintain Proper Levels of Hedgehog Signaling during Vertebrate Ocular Morphogenesis. PLoS Genet. 2014;10(7):e1004491. doi:10.1371/journal.pgen.1004491.

Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish

Authors:
Wei Y, Ma D, Gao Y, Zhang C, Wang L, Liu F
Citation:
Blood. 2014 Sep 4;124(10):1578-85. doi: 10.1182/blood-2013-11-541391. Epub 2014 Jul 8
Epub:
Not Epub
Abstract:
Nuclear receptor co-repressors (Ncor) are important for developmental and homeostatic processes in vertebrates, which exert...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei Y, Ma D, Gao Y, Zhang C, Wang L, Liu F. Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish. Blood. 2014 Sep 4;124(10):1578-85. doi: 10.1182/blood-2013-11-541391. Epub 2014 Jul 8.

WNK1/HSN2 isoform and the regulation of KCC2 activity

Authors:
Bercier V
Citation:
Rare Dis. 2013 Sep 19;1:e26537. doi: 10.4161/rdis.26537. eCollection 2013
Epub:
Not Epub
Abstract:
Hereditary sensory and autonomic neuropathy type 2 is a rare autosomal recessive pathology presenting with early onset...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bercier V. WNK1/HSN2 isoform and the regulation of KCC2 activity. Rare Dis. 2013 Sep 19;1:e26537. doi: 10.4161/rdis.26537. eCollection 2013.

aldh7a1 Regulates Eye and Limb Development in Zebrafish

Authors:
Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP
Citation:
PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014
Epub:
Not Epub
Abstract:
Uveal coloboma is a potentially blinding congenital ocular malformation caused by failure of the optic fissure to close during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP. aldh7a1 Regulates Eye and Limb Development in Zebrafish. PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014.

Smad signaling pathways regulate pancreatic endocrine development

Authors:
El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G
Citation:
Dev Biol. 2013 Jun 15;378(2):83-93. doi: 10.1016/j.ydbio.2013.04.003. Epub 2013 Apr 17
Epub:
Not Epub
Abstract:
Expansion of the pancreatic endocrine cell population occurs during both embryonic development and during post-natal pancreatic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
organ culture: mouse pancreas
Citation Extract:
El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G. Smad signaling pathways regulate pancreatic endocrine development. Dev Biol. 2013 Jun 15;378(2):83-93. doi: 10.1016/j.ydbio.2013.04.003. Epub 2013 Apr 17.

Calsyntenin-1 Regulates Axon Branching and Endosomal Trafficking during Sensory Neuron Development In Vivo

Authors:
Ponomareva OY, Holmen IC, Sperry AJ, Eliceiri KW, Halloran MC
Citation:
J Neurosci. 2014;34(28):9235-48 doi:10.1523/JNEUROSCI.0561-14.2014
Epub:
Not Epub
Abstract:
Precise regulation of axon branching is crucial for neuronal circuit formation, yet the mechanisms that control branch...
Organism or Cell Type:
zebrafish
Citation Extract:
Ponomareva OY, Holmen IC, Sperry AJ, Eliceiri KW, Halloran MC. Calsyntenin-1 Regulates Axon Branching and Endosomal Trafficking during Sensory Neuron Development In Vivo. J Neurosci. 2014;34(28):9235-48 doi:10.1523/JNEUROSCI.0561-14.2014.

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing

Authors:
Diaz-Horta O, Subasioglu-Uzak A, Grati M, DeSmidt A, Foster J 2nd, Cao L, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Abad C, Mittal R, Blanton S, Liu XZ, Farooq A, Walz K, Lu Z, Tekin M
Citation:
Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9864-8. doi: 10.1073/pnas.1401950111. Epub 2014 Jun 23
Epub:
Not Epub
Abstract:
In a large consanguineous Turkish kindred with recessive nonsyndromic, prelingual, profound hearing loss, we identified in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Diaz-Horta O, Subasioglu-Uzak A, Grati M, DeSmidt A, Foster J 2nd, Cao L, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Abad C, Mittal R, Blanton S, Liu XZ, Farooq A, Walz K, Lu Z, Tekin M. FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9864-8. doi: 10.1073/pnas.1401950111. Epub 2014 Jun 23.

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