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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

Authors:
Rasighaemi P, Onnebo SM, Liongue C, Ward AC
Citation:
Haematologica. 2015 Jan; 100(1): 23–31.
Epub:
Yes
Abstract:
Chromosomal translocations involving fusions of the human ETV6 (TEL1) gene occur frequently in hematological malignancies....
Link:
http://www.haematologica.org/content/early/2014/09/29/haematol.2014.104091
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rasighaemi P, Onnebo SM, Liongue C, Ward AC. ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish. Haematologica. 2015 Jan; 100(1): 23–31. .

RING finger protein RNF207, a novel regulator of cardiac excitation

Authors:
Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G
Citation:
J Biol Chem. 2014 Dec 5;289(49):33730-40. doi: 10.1074/jbc.M114.592295. Epub 2014 Oct 3. PMID: 25281747; PMCID: PMC4256309
Epub:
Yes
Abstract:
Two recent studies [Newton-Cheh et al., Nature Genetics 41, 399-406 (2009); Pfeufer et al., Nature Genetics 41, 407-414 (2009...
Link:
https://www.jbc.org/article/S0021-9258(20)47325-9/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G. RING finger protein RNF207, a novel regulator of cardiac excitation. J Biol Chem. 2014 Dec 5;289(49):33730-40. doi: 10.1074/jbc.M114.592295. Epub 2014 Oct 3. PMID: 25281747; PMCID: PMC4256309.

Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency

Authors:
Ruparelia AA, Oorschot V, Vaz R, Ramm G, Bryson-Richardson RJ
Citation:
Acta Neuropathol. 2014 Oct 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in the co-chaperone Bcl2-associated athanogene 3 (BAG3) can cause myofibrillar myopathy (MFM), a childhood-onset...
Link:
http://link.springer.com/article/10.1007%2Fs00401-014-1344-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ruparelia AA, Oorschot V, Vaz R, Ramm G, Bryson-Richardson RJ. Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency. Acta Neuropathol. 2014 Oct 2. [Epub ahead of print].

Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress

Authors:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF
Citation:
Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25
Epub:
Not Epub
Abstract:
Alcoholism induces folate deficiency and increases the risk for embryonic anomalies. However, the interplay between ethanol...
Link:
http://mcb.asm.org/content/34/3/498.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF. Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress. Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25.

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases

Authors:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G
Citation:
F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014
Epub:
Not Epub
Abstract:
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks...
Link:
http://f1000research.com/articles/3-121/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G. Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases. F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014.

Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics

Authors:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA
Citation:
Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27
Epub:
Not Epub
Abstract:
During embryonic development and tissue homeostasis, cells produce and remodel the extracellular matrix (ECM). The ECM...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725194/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA. Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics. Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27.

IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis

Authors:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X
Citation:
J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15
Epub:
Not Epub
Abstract:
Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon endoplasmic reticulum (ER) stress, IRE1...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102841/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X. IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis. J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15.

Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks

Authors:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF
Citation:
Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12
Epub:
Not Epub
Abstract:
Gene regulatory networks (GRNs) describe the progression of transcriptional states that take a single-celled zygote to a...
Link:
http://mbe.oxfordjournals.org/content/31/10/2672.long
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks. Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12.

Cholestenoic acids regulate motor neuron survival via liver X receptors

Authors:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y
Citation:
J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cholestenoic acids are formed as intermediates in metabolism of cholesterol to bile acids, and the biosynthetic enzymes that...
Link:
http://www.jci.org/articles/view/68506
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y. Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print].

Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression

Authors:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503
Epub:
Not Epub
Abstract:
CUL4A and CUL4B are closely related cullin family members and can each assemble a Cullin-RING E3 ligase complex (CRL) and...
Link:
http://hmg.oxfordjournals.org/content/early/2014/09/30/hmg.ddu503.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y. Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503.

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