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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration

Authors:
Rajaram K, Harding RL, Hyde DR, Patton JG
Citation:
Dev Biol. 2014 May 20. pii: S0012-1606(14)00260-7. doi: 10.1016/j.ydbio.2014.05.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Damage of the zebrafish retina triggers a spontaneous regeneration response that is initiated by Müller Glia (MG)...
Delivery Method:
injected then electroporated
Organism or Cell Type:
zebrafish
Citation Extract:
Rajaram K, Harding RL, Hyde DR, Patton JG. miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration. Dev Biol. 2014 May 20. pii: S0012-1606(14)00260-7. doi: 10.1016/j.ydbio.2014.05.005. [Epub ahead of print].

Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio

Authors:
Kumai Y, Porteus CS, Kwong RW, Perry SF
Citation:
Pflugers Arch. 2014 Jun 18. [Epub ahead of print]
Epub:
Yes
Abstract:
The present study investigated the role of hydrogen sulfide (H2S) in regulating Na+ uptake in larval zebrafish, Danio rerio....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Porteus CS, Kwong RW, Perry SF. Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio. Pflugers Arch. 2014 Jun 18. [Epub ahead of print].

Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms

Authors:
Mei X, Westfall TA, Zhang Q, Sheffield VC, Bassuk AG, Slusarski DC
Citation:
Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Ciliopathies are genetic disorders that are caused by dysfunctional cilia and affect multiple organs. One type of ciliopathy,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mei X, Westfall TA, Zhang Q, Sheffield VC, Bassuk AG, Slusarski DC. Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms. Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print].

RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

Authors:
Andrews OE, Cha DJ, Wei C, Patton JG
Citation:
Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222
Epub:
Not Epub
Abstract:
RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andrews OE, Cha DJ, Wei C, Patton JG. RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription. Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222.

Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia

Authors:
Zhang Z, Jia H, Zhang Q, Wan Y, Song B, Jia Q, Liu H, Zhu X, Fang A
Citation:
Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008
Epub:
Not Epub
Abstract:
To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Jia H, Zhang Q, Wan Y, Song B, Jia Q, Liu H, Zhu X, Fang A. Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia. Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008.

Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?

Authors:
Sampaio P, Ferreira RR, Guerrero A, Pintado P, Tavares B, Amaro J, Smith AA, Montenegro-Johnson T, Smith DJ, Lopes SS
Citation:
Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Internal organs are asymmetrically positioned inside the body. Embryonic motile cilia play an essential role in this process by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sampaio P, Ferreira RR, Guerrero A, Pintado P, Tavares B, Amaro J, Smith AA, Montenegro-Johnson T, Smith DJ, Lopes SS. Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?. Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print].

The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity

Authors:
Forn-Cuní G, Reis ES, Dios S, Posada D, Lambris JD, Figueras A, Novoa B
Citation:
PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673
Epub:
Not Epub
Abstract:
The complement system acts as a first line of defense and promotes organism homeostasis by modulating the fates of diverse...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Forn-Cuní G, Reis ES, Dios S, Posada D, Lambris JD, Figueras A, Novoa B. The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity. PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673.

tRNA synthetase counteracts c-Myc to develop functional vasculature

Authors:
Shi Y, Xu X, Zhang Q, Fu G, Mo Z, Wang GS, Kishi S, Yang X-L
Citation:
eLife. 2014;3:e02349 doi:10.7554/eLife.02349#sthash.RGoSMvJd.dpuf
Epub:
Not Epub
Abstract:
Recent studies suggested an essential role for seryl-tRNA synthetase (SerRS) in vascular development. This role is specific to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y, Xu X, Zhang Q, Fu G, Mo Z, Wang GS, Kishi S, Yang X-L. tRNA synthetase counteracts c-Myc to develop functional vasculature. eLife. 2014;3:e02349 doi:10.7554/eLife.02349#sthash.RGoSMvJd.dpuf.

Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates

Authors:
Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF.
Citation:
J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by the loss of survival of motor neuron (SMN)...
Delivery Method:
intracerebroventricular injection
Organism or Cell Type:
mice
Citation Extract:
Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF.. Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates. J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30.

Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish

Authors:
Liu D, Yu Y, Schachner M
Citation:
Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print]
Epub:
Yes
Abstract:
Based on the observation that the tumor suppressor gene PTEN (phosphatase and tensin homolog) reduces regeneration after spinal...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu D, Yu Y, Schachner M. Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish. Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print].

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