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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish

Authors:
Bai Y, Tan X, Zhang H, Liu C, Zhao B, Li Y, Lu L, Liu Y, Zhou J
Citation:
J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The receptor tyrosine kinase Ror2 acts as an alternative receptor or coreceptor for Wnt5a and mediates Wnt5a-induced convergent...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bai Y, Tan X, Zhang H, Liu C, Zhao B, Li Y, Lu L, Liu Y, Zhou J. Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish. J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print].

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Authors:
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, (authors deleted - database limit exceeded) Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ
Citation:
Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14
Epub:
Not Epub
Abstract:
Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, (authors deleted - database limit exceeded) Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14.

Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development

Authors:
Skobo T, Benato F, Grumati P, Meneghetti G, Cianfanelli V, Castagnaro S, Chrisam M, Di Bartolomeo S, Bonaldo P, Cecconi F, Valle LD
Citation:
PLoS One. 2014 Jun 12;9(6):e99210. doi: 10.1371/journal.pone.0099210. eCollection 2014
Epub:
Not Epub
Abstract:
The essential role of autophagy in muscle homeostasis has been clearly demonstrated by phenotype analysis of mice with muscle-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Skobo T, Benato F, Grumati P, Meneghetti G, Cianfanelli V, Castagnaro S, Chrisam M, Di Bartolomeo S, Bonaldo P, Cecconi F, Valle LD. Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development. PLoS One. 2014 Jun 12;9(6):e99210. doi: 10.1371/journal.pone.0099210. eCollection 2014.

Interferon-gamma directly mediates developmental biliary defects

Authors:
Cui S, Eauclaire SF, Matthews RP
Citation:
Zebrafish. 2013 Jun;10(2):177-83. doi: 10.1089/zeb.2012.0815. Epub 2013 Feb 28
Epub:
Not Epub
Abstract:
Biliary atresia (BA) is the most common identifiable hepatobiliary disease affecting infants, in which there are defects in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cui S, Eauclaire SF, Matthews RP. Interferon-gamma directly mediates developmental biliary defects. Zebrafish. 2013 Jun;10(2):177-83. doi: 10.1089/zeb.2012.0815. Epub 2013 Feb 28.

Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo

Authors:
Law AL, Vehlow A, Kotini M, Dodgson L, Soong D, Theveneau E, Bodo C, Taylor E, Navarro C, Perera U, Michael M, Dunn GA, Bennett D, Mayor R, Krause M
Citation:
J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18
Epub:
Not Epub
Abstract:
Cell migration is essential for development, but its deregulation causes metastasis. The Scar/WAVE complex is absolutely...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Law AL, Vehlow A, Kotini M, Dodgson L, Soong D, Theveneau E, Bodo C, Taylor E, Navarro C, Perera U, Michael M, Dunn GA, Bennett D, Mayor R, Krause M. Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo. J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18.

Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR

Authors:
Zhang Z, Feng J, Pan C, Lv X, Wu W, Zhou Z, Liu F, Zhang L, Zhao Y
Citation:
J Cell Biol. 2013 Nov 25;203(4):575-83. doi: 10.1083/jcb.201306012
Epub:
Not Epub
Abstract:
The evolutionarily conserved Hedgehog (Hh) signaling pathway is transduced by the Cubitus interruptus (Ci)/Gli family of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Feng J, Pan C, Lv X, Wu W, Zhou Z, Liu F, Zhang L, Zhao Y. Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR. J Cell Biol. 2013 Nov 25;203(4):575-83. doi: 10.1083/jcb.201306012.

Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization

Authors:
Campbell DS, Okamoto H
Citation:
J Cell Biol. 2013 Nov 25;203(4):657-72. doi: 10.1083/jcb.201303072
Epub:
Not Epub
Abstract:
In addition to being critical for apoptosis, components of the apoptotic pathway, such as caspases, are involved in other...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campbell DS, Okamoto H. Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization. J Cell Biol. 2013 Nov 25;203(4):657-72. doi: 10.1083/jcb.201303072.

Reverse engineering validation using a benchmark synthetic gene circuit in human cells

Authors:
Kang T, White JT, Xie Z, Benenson Y, Sontag E, Bleris L
Citation:
ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28
Epub:
Not Epub
Abstract:
Multicomponent biological networks are often understood incompletely, in large part due to the lack of reliable and robust...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Kang T, White JT, Xie Z, Benenson Y, Sontag E, Bleris L. Reverse engineering validation using a benchmark synthetic gene circuit in human cells. ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28.

Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation

Authors:
Streets AJ, Wessely O, Peters DJ, Ong AC
Citation:
Hum Mol Genet. 2013 May 15;22(10):1924-39. doi: 10.1093/hmg/ddt031. Epub 2013 Feb 5
Epub:
Not Epub
Abstract:
Mutations in PKD1 (85%) or PKD2 (15%) account for almost all cases of autosomal dominant polycystic kidney disease (ADPKD). The...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Streets AJ, Wessely O, Peters DJ, Ong AC. Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. Hum Mol Genet. 2013 May 15;22(10):1924-39. doi: 10.1093/hmg/ddt031. Epub 2013 Feb 5.

The Giardia cell cycle progresses independently of the anaphase-promoting complex

Authors:
Gourguechon S, Holt LJ, Cande WZ
Citation:
J Cell Sci. 2013 May 15;126(Pt 10):2246-55. doi: 10.1242/jcs.121632. Epub 2013 Mar 22
Epub:
Not Epub
Abstract:
Most cell cycle regulation research has been conducted in model organisms representing a very small part of the eukaryotic...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia intestinalis
Citation Extract:
Gourguechon S, Holt LJ, Cande WZ. The Giardia cell cycle progresses independently of the anaphase-promoting complex. J Cell Sci. 2013 May 15;126(Pt 10):2246-55. doi: 10.1242/jcs.121632. Epub 2013 Mar 22.

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