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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation

Authors:
Heinke J, Juschkat M, Charlet A, Mnich L, Helbing T, Bode C, Patterson C, Moser M
Citation:
J Cell Sci. 2013 Jul 15;126(Pt 14):3082-94. doi: 10.1242/jcs.122333. Epub 2013 May 2
Epub:
Not Epub
Abstract:
Growth and regeneration of blood vessels are crucial processes during embryonic development and in adult disease. Members of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heinke J, Juschkat M, Charlet A, Mnich L, Helbing T, Bode C, Patterson C, Moser M. Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation. J Cell Sci. 2013 Jul 15;126(Pt 14):3082-94. doi: 10.1242/jcs.122333. Epub 2013 May 2.

DAX1 regulatory networks unveil conserved and potentially new functions

Authors:
Martins RS, Power DM, Fuentes J, Deloffre LA, Canário AV
Citation:
Gene. 2013 Nov 1;530(1):66-74. doi: 10.1016/j.gene.2013.07.052. Epub 2013 Aug 14
Epub:
Not Epub
Abstract:
DAX1 is an orphan nuclear receptor with actions in mammalian sex determination, regulation of steroidogenesis, embryonic...
Citation Extract:
Martins RS, Power DM, Fuentes J, Deloffre LA, Canário AV. DAX1 regulatory networks unveil conserved and potentially new functions. Gene. 2013 Nov 1;530(1):66-74. doi: 10.1016/j.gene.2013.07.052. Epub 2013 Aug 14.

Zebrafish as a model to study PTPs during development

Authors:
Paardekooper Overman J, den Hertog J
Citation:
Methods. 2014 Jan 15;65(2):247-53. doi: 10.1016/j.ymeth.2013.08.018. Epub 2013 Aug 22
Epub:
Not Epub
Abstract:
Protein-tyrosine phosphatases (PTPs) have important roles in signaling, but relatively little is known about their function in...
Organism or Cell Type:
zebrafish
Citation Extract:
Paardekooper Overman J, den Hertog J. Zebrafish as a model to study PTPs during development. Methods. 2014 Jan 15;65(2):247-53. doi: 10.1016/j.ymeth.2013.08.018. Epub 2013 Aug 22.

LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys

Authors:
Burghardt T, Kastner J, Suleiman H, Rivera-Milla E, Stepanova N, Lottaz C, Kubitza M, Böger CA, Schmidt S, Gorski M, de Vries U, Schmidt H, Hertting I, Kopp J, Rascle A, Moser M, Heid IM, Warth R, Spang R, Wegener J, Mierke CT, Englert C, Witzgall R
Citation:
J Am Soc Nephrol. 2013 Nov;24(11):1830-48. doi: 10.1681/ASN.2012080788. Epub 2013 Aug 29
Epub:
Not Epub
Abstract:
Mutations of the LMX1B gene cause nail-patella syndrome, a rare autosomal-dominant disorder affecting the development of the...
Organism or Cell Type:
zebrafish
Citation Extract:
Burghardt T, Kastner J, Suleiman H, Rivera-Milla E, Stepanova N, Lottaz C, Kubitza M, Böger CA, Schmidt S, Gorski M, de Vries U, Schmidt H, Hertting I, Kopp J, Rascle A, Moser M, Heid IM, Warth R, Spang R, Wegener J, Mierke CT, Englert C, Witzgall R. LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. J Am Soc Nephrol. 2013 Nov;24(11):1830-48. doi: 10.1681/ASN.2012080788. Epub 2013 Aug 29.

IL-22 is a key player in the regulation of inflammation in fish and involves innate immune cells and PI3K signaling

Authors:
Costa MM, Saraceni PR, Forn-Cuní G, Dios S, Romero A, Figueras A, Novoa B
Citation:
Dev Comp Immunol. 2013 Dec;41(4):746-55. doi: 10.1016/j.dci.2013.08.021. Epub 2013 Aug 30
Epub:
Not Epub
Abstract:
IL-22 plays a role in various disorders in mammals, including mucosal-associated infections and inflammatory diseases. No...
Organism or Cell Type:
zebrafish
Citation Extract:
Costa MM, Saraceni PR, Forn-Cuní G, Dios S, Romero A, Figueras A, Novoa B. IL-22 is a key player in the regulation of inflammation in fish and involves innate immune cells and PI3K signaling. Dev Comp Immunol. 2013 Dec;41(4):746-55. doi: 10.1016/j.dci.2013.08.021. Epub 2013 Aug 30.

Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion

Authors:
Ebert AM, Childs SJ, Hehr CL, Cechmanek PB, McFarlane S
Citation:
Development. 2014;141:2473-2482. doi:10.1242/dev.103499
Epub:
Not Epub
Abstract:
Organs are generated from collections of cells that coalesce and remain together as they undergo a series of choreographed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ebert AM, Childs SJ, Hehr CL, Cechmanek PB, McFarlane S. Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion. Development. 2014;141:2473-2482. doi:10.1242/dev.103499 .

A dynamic regulatory network explains ParaHox gene control of gut patterning in the sea urchin

Authors:
Annunziata R, Arnone MI
Citation:
Development. 2014 May 21. pii: dev.105775. [Epub ahead of print]
Epub:
Yes
Abstract:
The anteroposterior patterning of the embryonic gut represents one of the most intriguing biological processes in development....
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Annunziata R, Arnone MI. A dynamic regulatory network explains ParaHox gene control of gut patterning in the sea urchin. Development. 2014 May 21. pii: dev.105775. [Epub ahead of print].

Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition

Authors:
Clay MR, Halloran MC
Citation:
Development 2014 141:2506-2515; doi:10.1242/dev.105551
Epub:
Not Epub
Abstract:
The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Clay MR, Halloran MC. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. Development 2014 141:2506-2515; doi:10.1242/dev.105551.

Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+‐CaMKII‐Regulated Induction of HDAC3

Authors:
Sharifi‐Sanjani M, Shoushtari AH, Quiroz M, Baust J, Sestito SF, Mosher M, Ross M, McTiernan CF, St. Croix CM, Bilonick RA, Champion HC, Isenberg JS
Citation:
J Am Heart Assoc. 2014;3:e000670, originally published June 10, 2014, doi:10.1161/JAHA.113.000670
Epub:
Yes
Abstract:
Background: Left ventricular heart failure (LVHF) remains progressive and fatal and is a formidable health problem because ever...
Delivery Method:
cell bathing in culture, injection in vivo
Organism or Cell Type:
cell culture: rat neonatal cardiac myocytes (RNMC), mice C57BL/6
Citation Extract:
Sharifi‐Sanjani M, Shoushtari AH, Quiroz M, Baust J, Sestito SF, Mosher M, Ross M, McTiernan CF, St. Croix CM, Bilonick RA, Champion HC, Isenberg JS. Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+‐CaMKII‐Regulated Induction of HDAC3. J Am Heart Assoc. 2014;3:e000670, originally published June 10, 2014, doi:10.1161/JAHA.113.000670 .

TLR7 is a key regulator of innate immunity against Japanese Encephalitis Virus infection

Authors:
Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A
Citation:
Neurobiol Dis. 2014 Sep;69:235-47. doi: 10.1016/j.nbd.2014.05.036. Epub 2014 Jun 5.
Epub:
Not Epub
Abstract:
Toll-like receptor 7 (TLR7) known to recognize guanidine-rich ssRNA has been shown to mount vital host defense mechanism...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A. TLR7 is a key regulator of innate immunity against Japanese Encephalitis Virus infection. Neurobiol Dis. 2014 Sep;69:235-47. doi: 10.1016/j.nbd.2014.05.036. Epub 2014 Jun 5..

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