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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12175 scientific papers returned from the database with the search filters currently being used below.
There are 12175 scientific papers returned from the database with the search filters currently being used below.
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans
Citation:
Am J Hum Genet. 2013 Nov 7;93(5):915-25. doi: 10.1016/j.ajhg.2013.09.012. Epub 2013 Oct 17 Epub:
Not Epub Abstract:
Intraflagellar transport (IFT) depends on two evolutionarily conserved modules, subcomplexes A (IFT-A) and B (IFT-B), to drive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Halbritter J, Bizet AA, Schmidts M, Porath JD, Braun DA, Gee HY, McInerney-Leo AM, Krug P, Filhol E, Davis EE, Airik R, Czarnecki PG, Lehman AM, Trnka P, Nitschké P, Bole-Feysot C, Schueler M, Knebelmann B, Burtey S, Szabó AJ, Tory K, Leo PJ, Gardiner B, McKenzie FA, Zankl A, Brown MA, Hartley JL, Maher ER, Li C, Leroux MR, Scambler PJ, Zhan SH, Jones SJ, Kayserili H, Tuysuz B, Moorani KN, Constantinescu A, Krantz ID, Kaplan BS, Shah JV; UK10K Consortium, Hurd TW, Doherty D, Katsanis N, Duncan EL, Otto EA, Beales PL, Mitchison HM, Saunier S, Hildebrandt F. Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. Am J Hum Genet. 2013 Nov 7;93(5):915-25. doi: 10.1016/j.ajhg.2013.09.012. Epub 2013 Oct 17. |
SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant
Citation:
Am J Hum Genet. 2013 Nov 7;93(5):798-811. doi: 10.1016/j.ajhg.2013.09.010. Epub 2013 Oct 17. Erratum in: Am J Hum Genet. 2013 Nov 7;93(5):994 Epub:
Not Epub Abstract:
Copy-number variants (CNVs) represent a significant interpretative challenge, given that each CNV typically affects the dosage... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dauber A, Golzio C, Guenot C, Jodelka FM, Kibaek M, Kjaergaard S, Leheup B, Martinet D, Nowaczyk MJ, Rosenfeld JA, Zeesman S, Zunich J, Beckmann JS, Hirschhorn JN, Hastings ML, Jacquemont S, Katsanis N. SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant. Am J Hum Genet. 2013 Nov 7;93(5):798-811. doi: 10.1016/j.ajhg.2013.09.010. Epub 2013 Oct 17. Erratum in: Am J Hum Genet. 2013 Nov 7;93(5):994. |
Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway
Citation:
Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19921-6. doi: 10.1073/pnas.1007256107. Epub 2010 Oct 27 Epub:
Not Epub Abstract:
Inositol phosphate (IP) kinases constitute an emerging class of cellular kinases linked to multiple cellular activities. Here,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sarmah B, Wente SR. Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19921-6. doi: 10.1073/pnas.1007256107. Epub 2010 Oct 27. |
Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2
Citation:
J Biol Chem. 2011 Apr 8;286(14):12093-100. doi: 10.1074/jbc.M110.185280. Epub 2011 Feb 1 Epub:
Not Epub Abstract:
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Hikasa H, Sokol SY. Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2. J Biol Chem. 2011 Apr 8;286(14):12093-100. doi: 10.1074/jbc.M110.185280. Epub 2011 Feb 1. |
Adenosine Prevents TNFα-Induced Decrease in Endothelial Mitochondrial Mass via Activation of eNOS-PGC-1α Regulatory Axis
Citation:
PLoS ONE. 2014;9(6):e98459. doi:10.1371/journal.pone.0098459 Epub:
Not Epub Abstract:
We tested whether adenosine, a cytoprotective mediator and trigger of preconditioning, could protect endothelial cells from... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human dermal microvascular endothelial cells (HMEC-1) Citation Extract: Kalogeris TJ, Baines C, Korthuis RJ. Adenosine Prevents TNFα-Induced Decrease in Endothelial Mitochondrial Mass via Activation of eNOS-PGC-1α Regulatory Axis. PLoS ONE. 2014;9(6):e98459. doi:10.1371/journal.pone.0098459. |
The apoptotic regulator Nrz controls cytoskeletal dynamics via the regulation of Ca2+ trafficking in the zebrafish blastula
Citation:
Dev Cell. 2011 May 17;20(5):663-76. doi: 10.1016/j.devcel.2011.03.016 Epub:
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Bcl-2 family members are key regulators of apoptosis. Their involvement in other cellular processes has been so far overlooked... Organism or Cell Type:
zebrafish Citation Extract: Popgeorgiev N, Bonneau B, Ferri KF, Prudent J, Thibaut J, Gillet G. The apoptotic regulator Nrz controls cytoskeletal dynamics via the regulation of Ca2+ trafficking in the zebrafish blastula. Dev Cell. 2011 May 17;20(5):663-76. doi: 10.1016/j.devcel.2011.03.016. |
Transcription factor COUP-TFII is indispensable for venous and lymphatic development in zebrafish and Xenopus laevis
Citation:
Biochem Biophys Res Commun. 2011 Jun 24;410(1):121-6. doi: 10.1016/j.bbrc.2011.05.117. Epub 2011 May 27 Epub:
Not Epub Abstract:
Transcription factors play a central role in cell fate determination. Gene targeting in mice revealed that Chicken Ovalbumin... Citation Extract: Aranguren XL, Beerens M, Vandevelde W, Dewerchin M, Carmeliet P, Luttun A. Transcription factor COUP-TFII is indispensable for venous and lymphatic development in zebrafish and Xenopus laevis. Biochem Biophys Res Commun. 2011 Jun 24;410(1):121-6. doi: 10.1016/j.bbrc.2011.05.117. Epub 2011 May 27. |
Protein tyrosine phosphatase σ regulates the synapse number of zebrafish olfactory sensory neurons
Citation:
J Neurochem. 2011 Nov;119(3):532-43. doi: 10.1111/j.1471-4159.2011.07411.x. Epub 2011 Aug 29 Epub:
Not Epub Abstract:
The formation and refinement of synaptic connections are key steps of neural development to establish elaborate brain networks... Organism or Cell Type:
zebrafish Citation Extract: Chen X, Yoshida T, Sagara H, Mikami Y, Mishina M. Protein tyrosine phosphatase σ regulates the synapse number of zebrafish olfactory sensory neurons. J Neurochem. 2011 Nov;119(3):532-43. doi: 10.1111/j.1471-4159.2011.07411.x. Epub 2011 Aug 29. |
Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37
Citation:
Chem Biol. 2011 Oct 28;18(10):1300-11. doi: 10.1016/j.chembiol.2011.07.020 Epub:
Not Epub Abstract:
Identification of methionine aminopeptidase-2 (MetAP-2) as the molecular target of the antiangiogenic compound TNP-470 has... Organism or Cell Type:
zebrafish Citation Extract: Sundberg TB, Darricarrere N, Cirone P, Li X, McDonald L, Mei X, Westlake CJ, Slusarski DC, Beynon RJ, Crews CM. Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37. Chem Biol. 2011 Oct 28;18(10):1300-11. doi: 10.1016/j.chembiol.2011.07.020. |
Essential role of Fbxl14 ubiquitin ligase in regulation of vertebrate axis formation through modulating Mkp3 level
Citation:
Cell Res. 2012 May;22(5):936-40. doi: 10.1038/cr.2012.37. Epub 2012 Mar 13. No abstract available Epub:
Not Epub Abstract:
The F-box family of proteins (FBPs), the substrate-recognition components of the Skp1-Cul1-F-box-protein (SCF) ubiquitin ligase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zheng H, Du Y, Hua Y, Wu Z, Yan Y, Li Y. Essential role of Fbxl14 ubiquitin ligase in regulation of vertebrate axis formation through modulating Mkp3 level. Cell Res. 2012 May;22(5):936-40. doi: 10.1038/cr.2012.37. Epub 2012 Mar 13. No abstract available. |