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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish

Authors:
Wu BJ, Chiu CC, Chen CL, Wang WD, Wang JH, Wen ZH, Liu W, Chang HW, Wu CY
Citation:
PLoS One. 2014 Aug 26;9(8):e105939. doi: 10.1371/journal.pone.0105939. eCollection 2014
Epub:
Not Epub
Abstract:
Genetic regulators and signaling pathways are important for the formation of blood vessels. Transcription factors controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu BJ, Chiu CC, Chen CL, Wang WD, Wang JH, Wen ZH, Liu W, Chang HW, Wu CY. Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish. PLoS One. 2014 Aug 26;9(8):e105939. doi: 10.1371/journal.pone.0105939. eCollection 2014.

Ncor1 and Ncor2 Play essential but distinct roles in zebrafish primitive myelopoiesis

Authors:
Li J, Li K, Dong X, Liang D, Zhao Q
Citation:
Dev Dyn. 2014 Aug 26. doi: 10.1002/dvdy.24181. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Though Ncor1 and Ncor2, the co-repressors that can actively repress gene transcription through binding nuclear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Li K, Dong X, Liang D, Zhao Q. Ncor1 and Ncor2 Play essential but distinct roles in zebrafish primitive myelopoiesis. Dev Dyn. 2014 Aug 26. doi: 10.1002/dvdy.24181. [Epub ahead of print].

Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies

Authors:
Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E
Citation:
Antimicrob Agents Chemother. 2014 Nov;58(11):6639-47. doi: 10.1128/AAC.03442-14. Epub 2014 Aug 25. PMID: 25155593; PMCID: PMC4249403
Epub:
Yes
Abstract:
Two identical single ascending dose (SAD) studies evaluated the safety and pharmacokinetics (PK) of AVI-6002 and AVI-6003, two...
Delivery Method:
iv infusion
Organism or Cell Type:
human
Citation Extract:
Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E. Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies. Antimicrob Agents Chemother. 2014 Nov;58(11):6639-47. doi: 10.1128/AAC.03442-14. Epub 2014 Aug 25. PMID: 25155593; PMCID: PMC4249403.

miR-142-3p acts as an essential modulator of neutrophil development in zebrafish

Authors:
Fan HB, Liu YJ, Wang L, Du TT, Dong M, Gao L, Meng ZZ, Jin Y, Chen Y, Deng M, Yang HT, Jing Q, Gu AH, Liu TX, Zhou Y
Citation:
Blood. 2014 Aug 21;124(8):1320-30. doi: 10.1182/blood-2013-12-545012. Epub 2014 Jul 2
Epub:
Yes
Abstract:
Neutrophils play critical roles in vertebrate innate immune responses. As an emerging regulator in normal myelopoiesis, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fan HB, Liu YJ, Wang L, Du TT, Dong M, Gao L, Meng ZZ, Jin Y, Chen Y, Deng M, Yang HT, Jing Q, Gu AH, Liu TX, Zhou Y. miR-142-3p acts as an essential modulator of neutrophil development in zebrafish. Blood. 2014 Aug 21;124(8):1320-30. doi: 10.1182/blood-2013-12-545012. Epub 2014 Jul 2.

Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins

Authors:
Feng Y, Gross S, Wolf NM, Butenschön VM, Qiu Y, Devraj K, Liebner S, Kroll J, Skolnik EY, Hammes H-P, Wieland T
Citation:
Arterioscler Thromb Vasc Biol. 2014;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304239
Epub:
Yes
Abstract:
Objective: Nucleoside diphosphate kinase B (NDPKB) participates in the activation of heterotrimeric and monomeric G proteins,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng Y, Gross S, Wolf NM, Butenschön VM, Qiu Y, Devraj K, Liebner S, Kroll J, Skolnik EY, Hammes H-P, Wieland T. Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins. Arterioscler Thromb Vasc Biol. 2014;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304239 .

Shear Stress-Activated Wnt-Angiopoietin-2 Signaling Recapitulated Vascular Repair in Zebrafish Embryos

Authors:
Li R, Beebe T, Jen N, Yu F, Takabe W, Harrison M, Cao H, Lee J, Yang H, Han P, Wang K, Shimizu H, Chen J, Lien C-L, Chi NC, Hsiai TK
Citation:
Arterioscler Thromb Vasc Biol. 2014;[Epub ahead of print] doi:10.1161/ATVBAHA.114.303345
Epub:
Yes
Abstract:
Objective: Fluid shear stress intimately regulates vasculogenesis and endothelial homeostasis. The canonical Wnt/β-catenin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li R, Beebe T, Jen N, Yu F, Takabe W, Harrison M, Cao H, Lee J, Yang H, Han P, Wang K, Shimizu H, Chen J, Lien C-L, Chi NC, Hsiai TK. Shear Stress-Activated Wnt-Angiopoietin-2 Signaling Recapitulated Vascular Repair in Zebrafish Embryos. Arterioscler Thromb Vasc Biol. 2014;[Epub ahead of print] doi:10.1161/ATVBAHA.114.303345 .

The Par-PrkC Polarity Complex Is Required for Cilia Growth in Zebrafish Photoreceptors

Authors:
Krock BL, Perkins BD
Citation:
PLoS One. 2014 Aug 21;9(8):e104661. doi: 10.1371/journal.pone.0104661. eCollection 2014
Epub:
Not Epub
Abstract:
Specification and development of the apical membrane in epithelial cells requires the function of polarity proteins, including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krock BL, Perkins BD. The Par-PrkC Polarity Complex Is Required for Cilia Growth in Zebrafish Photoreceptors. PLoS One. 2014 Aug 21;9(8):e104661. doi: 10.1371/journal.pone.0104661. eCollection 2014.

Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling

Authors:
Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D
Citation:
Nature. 2014 Aug 13. doi: 10.1038/nature13623. [Epub ahead of print]
Epub:
Yes
Abstract:
Notch signalling plays a key role in the generation of haematopoietic stem cells (HSCs) during vertebrate development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D. Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 2014 Aug 13. doi: 10.1038/nature13623. [Epub ahead of print].

Impaired Development Of Neural-Crest Cell Derived Organs and Intellectual Disability Caused By MED13L Haploinsufficiency

Authors:
Utami KH, Winata CL, Hillmer AM, Aksoy I, Long HT, Liany H, Yan EC, Mathavan S, Hong ST, Korzh V, Sarda P, Davila S, Cacheux V
Citation:
Hum Mutat. 2014 Aug 18. doi: 10.1002/humu.22636. [Epub ahead of print]
Epub:
Yes
Abstract:
MED13L is a component subunit of the Mediator complex, an important regulator of transcription that is highly conserved across...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Utami KH, Winata CL, Hillmer AM, Aksoy I, Long HT, Liany H, Yan EC, Mathavan S, Hong ST, Korzh V, Sarda P, Davila S, Cacheux V. Impaired Development Of Neural-Crest Cell Derived Organs and Intellectual Disability Caused By MED13L Haploinsufficiency. Hum Mutat. 2014 Aug 18. doi: 10.1002/humu.22636. [Epub ahead of print].

The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells

Authors:
Yang Z, Augustin J, Chang C, Hu J, Shah K, Chang C-W, Townes T, Jiang H
Citation:
Blood. 2014 Sep 25;124(13):2025-33. doi: 10.1182/blood-2014-01-549220. Epub 2014 Aug 18.
Epub:
Not Epub
Abstract:
Epigenetic mechanisms, including histone modifications, have emerged as important factors influencing cell fate determination....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Z, Augustin J, Chang C, Hu J, Shah K, Chang C-W, Townes T, Jiang H. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells. Blood. 2014 Sep 25;124(13):2025-33. doi: 10.1182/blood-2014-01-549220. Epub 2014 Aug 18..

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