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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Maternal thyroid hormones are essential for neural development in zebrafish

Authors:
Campinho MA, Saraiva J, Florindo C, Power DM
Citation:
Mol Endocrinol. 2014 May 30:me20141032. [Epub ahead of print]
Epub:
Yes
Abstract:
Teleost eggs contain an abundant store of maternal thyroid hormones (THs) and early in zebrafish embryonic development all the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campinho MA, Saraiva J, Florindo C, Power DM. Maternal thyroid hormones are essential for neural development in zebrafish. Mol Endocrinol. 2014 May 30:me20141032. [Epub ahead of print].

Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus

Authors:
Tahir R, Kennedy A, Elsea SH, Dickinson AJ
Citation:
Mech Dev. 2014 May 27. pii: S0925-4773(14)00028-8. doi: 10.1016/j.mod.2014.05.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid induced-1 (RAI1) is an important yet understudied histone code reader that when mutated in humans results in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tahir R, Kennedy A, Elsea SH, Dickinson AJ. Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus. Mech Dev. 2014 May 27. pii: S0925-4773(14)00028-8. doi: 10.1016/j.mod.2014.05.004. [Epub ahead of print].

Hedgehog-PKA Signaling and gnrh3 Regulate the Development of Zebrafish gnrh3 Neurons

Authors:
Kuo M-W, Lou S-W, Chung B-c
Citation:
PLoS ONE. 2014;9(5):e95545. doi:10.1371/journal.pone.0095545
Epub:
Not Epub
Abstract:
GnRH neurons secrete GnRH that controls the development of the reproduction system. Despite many studies, the signals...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuo M-W, Lou S-W, Chung B-c. Hedgehog-PKA Signaling and gnrh3 Regulate the Development of Zebrafish gnrh3 Neurons. PLoS ONE. 2014;9(5):e95545. doi:10.1371/journal.pone.0095545.

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro

Authors:
Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A
Citation:
Development 2014 141:2216-2224; posted ahead of print May 12, 2014, doi:10.1242/dev.106377
Epub:
Not Epub
Abstract:
Generation of neurons from patient fibroblasts using a combination of developmentally defined transcription factors has great...
Organism or Cell Type:
Xenopus
Citation Extract:
Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A. The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development 2014 141:2216-2224; posted ahead of print May 12, 2014, doi:10.1242/dev.106377.

Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish

Authors:
Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC
Citation:
PLoS Genet. 2014;10(5):e1004335
Epub:
Not Epub
Abstract:
Fatty liver disease (FLD) is characterized by lipid accumulation in hepatocytes and is accompanied by secretory pathway...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC. Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish. PLoS Genet. 2014;10(5):e1004335.

Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma

Authors:
Ulmer Carnes M, Liu YP, Allingham RR, Whigham BT, Havens S, Garrett ME, Qiao C, NEIGHBORHOOD Consortium Investigators, Katsanis N, Wiggs JL, Pasquale LR, Ashley-Koch A, Oh EC, Hauser MA
Citation:
PLoS Genet. 2014;10(5):e1004372. doi:10.1371/journal.pgen.1004372
Epub:
Not Epub
Abstract:
Glaucoma is a leading cause of blindness worldwide. Primary open-angle glaucoma (POAG) is the most common subtype and is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ulmer Carnes M, Liu YP, Allingham RR, Whigham BT, Havens S, Garrett ME, Qiao C, NEIGHBORHOOD Consortium Investigators, Katsanis N, Wiggs JL, Pasquale LR, Ashley-Koch A, Oh EC, Hauser MA. Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma. PLoS Genet. 2014;10(5):e1004372. doi:10.1371/journal.pgen.1004372.

Knockdown of mitogen-activated protein kinase (MAPK) signalling in the midgut of Anopheles stephensi mosquitoes using antisense morpholinos

Authors:
Pietri JE, Cheung KW, Luckhart S
Citation:
Insect Mol Biol. 2014 May 28. doi: 10.1111/imb.12103. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Arthropod-borne infectious diseases are responsible for nearly 1.5 million deaths annually across the globe, with malaria...
Delivery Method:
feeding
Organism or Cell Type:
Anopheles stephensi mosquito
Citation Extract:
Pietri JE, Cheung KW, Luckhart S. Knockdown of mitogen-activated protein kinase (MAPK) signalling in the midgut of Anopheles stephensi mosquitoes using antisense morpholinos. Insect Mol Biol. 2014 May 28. doi: 10.1111/imb.12103. [Epub ahead of print].

Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish

Authors:
Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL
Citation:
Aquat Toxicol. 2014 May 16;154C:71-79. doi: 10.1016/j.aquatox.2014.05.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Firemaster 550 (FM550) is an additive flame retardant mixture used within polyurethane foam and is increasingly found in house...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL. Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish. Aquat Toxicol. 2014 May 16;154C:71-79. doi: 10.1016/j.aquatox.2014.05.007. [Epub ahead of print].

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

Authors:
Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, Powell AE, Starchenko A, Ayers GD, Washington MK, Kamath V, Desai K, Gerdes MJ, Solnica-Krezel L, Coffey RJ
Citation:
J Clin Invest. 2014 Apr 1. pii: 71103. doi: 10.1172/JCI71103. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The epithelial-to-mesenchymal transition (EMT) transcriptional program is characterized by repression of E-cadherin (CDH1) and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, Powell AE, Starchenko A, Ayers GD, Washington MK, Kamath V, Desai K, Gerdes MJ, Solnica-Krezel L, Coffey RJ. Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J Clin Invest. 2014 Apr 1. pii: 71103. doi: 10.1172/JCI71103. [Epub ahead of print].

Intraperitoneal Injection is Not Always a Suitable Alternative to Intravenous Injection for Radiotherapy

Authors:
Dou S, Smith M, Wang Y, Rusckowski M, Liu G
Citation:
Cancer Biother Radiopharm. 2013;28(4):335-42. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Intraperitoneal (IP) injection is frequently reported to be as effective as intravenous (IV) injection. Because it allows...
Delivery Method:
injection
Organism or Cell Type:
mice
Citation Extract:
Dou S, Smith M, Wang Y, Rusckowski M, Liu G. Intraperitoneal Injection is Not Always a Suitable Alternative to Intravenous Injection for Radiotherapy. Cancer Biother Radiopharm. 2013;28(4):335-42. [Epub ahead of print].

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