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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells
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Citation:
BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x Epub:
Not Epub Abstract:
Background: The three members of the human heterochromatin protein 1 (HP1) family of proteins, HP1α, HP1β, and HPγ, are... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MDA-MB-231 Citation Extract: Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL. Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x. |
Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling
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Citation:
Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print] Epub:
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EFHC1 encodes a ciliary protein that has been linked to Juvenile Myoclonic Epilepsy. In ectodermal explants, derived from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Zhao Y, Shi J, Winey M, Klymkowsky MW. Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling. Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print]. |
Microtubule-associated protein 1b is required for shaping the neural tube
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Citation:
Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4 Epub:
Not Epub Abstract:
BACKGROUND: Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jayachandran P, Olmo VN, Sanchez SP, McFarland RJ, Vital E, Werner JM, Hong E, Sanchez-Alberola N, Molodstov A, Brewster RM. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4. |
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development
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Citation:
BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5 Epub:
Not Epub Abstract:
Background: Bone morphogenetic proteins regulate multiple processes in embryonic development, including early dorso-ventral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schille C, Heller J, Schambony A. Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development. BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5. |
Evolution of the fish heart by sub/neofunctionalization of an elastin gene
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Citation:
Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397 Epub:
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The evolution of phenotypic traits is a key process in diversification of life. However, the mechanisms underlying the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moriyama Y, Ito F, Takeda H, Yano T, Okabe M, Kuraku S, Keeley FW, Koshiba-Takeuchi K. Evolution of the fish heart by sub/neofunctionalization of an elastin gene. Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397. |
The morpholino molecular beacon for specific RNA visualization in vivo.
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Citation:
Chem Commun (Camb). 2016 Feb 21;52(15):3191-4. doi: 10.1039/c5cc07124k Epub:
Yes Abstract:
A non-invasive fluorescent probe, morpholino molecular beacon (MO-MB), was designed for RNA visualization in vivo. Featuring... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Chen J, Wu J, Hong Y. The morpholino molecular beacon for specific RNA visualization in vivo.. Chem Commun (Camb). 2016 Feb 21;52(15):3191-4. doi: 10.1039/c5cc07124k. |
A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions
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Citation:
Ophthalmol. 2016;[Epub ahead of print] doi:10.1016/j.ophtha.2015.12.008 Epub:
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Purpose: Corneal dystrophies are a genetically heterogeneous group of disorders. We previously described a family with an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oliver VF, van Bysterveldt KA, Cadzow M, Steger B, Romano V, Markie D, Hewitt AW, Mackey DA, Willoughby CE, Sherwin T, Crosier PS, McGhee CN, Vincent AL. A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions. Ophthalmol. 2016;[Epub ahead of print] doi:10.1016/j.ophtha.2015.12.008. |
An oxygen-insensitive Hif-3a isoform inhibits Wnt signaling by destabilizing the nuclear b-catenin complex
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Citation:
eLife. 2016;10.7554/eLife.08996 doi:10.7554/eLife.08996 Epub:
Not Epub Abstract:
Hypoxia-inducible factors (HIFs), while best known for their roles in the hypoxic response, have oxygen-independent roles in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang P, Bai Y, Lu L, Li Y, Duan C. An oxygen-insensitive Hif-3a isoform inhibits Wnt signaling by destabilizing the nuclear b-catenin complex. eLife. 2016;10.7554/eLife.08996 doi:10.7554/eLife.08996. |
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes
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Citation:
Nucleic Acids Res. 1997 Nov 15;25(22):4429-43 Epub:
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In an effort to discover novel oligonucleotide modifications for antisense therapeutics, we have prepared... Citation Extract: Freier SM, Altmann KH . The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes. Nucleic Acids Res. 1997 Nov 15;25(22):4429-43. |
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
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Citation:
Nat Comm. 2016;7:10310. doi:10.1038/ncomms10318 Epub:
Not Epub Abstract:
The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial role in embryonic development. Recent work has... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg J-P. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer. Nat Comm. 2016;7:10310. doi:10.1038/ncomms10318. |