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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Reducing synuclein accumulation improves neuronal survival after spinal cord injury

Authors:
Fogerson SM, van Brummen AJ, Busch DJ, Allen SR, Roychaudhuri R, Banks SM, Klärner FG, Schrader T, Bitan G, Morgan JR
Citation:
Exp Neurol. 2016 Feb 5. pii: S0014-4886(16)30026-7. doi: 10.1016/j.expneurol.2016.02.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Spinal cord injury causes neuronal death, limiting subsequent regeneration and recovery. Thus, there is a need to develop...
Organism or Cell Type:
lamprey
Citation Extract:
Fogerson SM, van Brummen AJ, Busch DJ, Allen SR, Roychaudhuri R, Banks SM, Klärner FG, Schrader T, Bitan G, Morgan JR. Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Exp Neurol. 2016 Feb 5. pii: S0014-4886(16)30026-7. doi: 10.1016/j.expneurol.2016.02.004. [Epub ahead of print].

Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders

Authors:
Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ
Citation:
Toxicol Appl Pharmacol. 2016 Feb 4. pii: S0041-008X(16)30024-2. doi: 10.1016/j.taap.2016.02.001. [Epub ahead of print]
Epub:
Yes
Abstract:
Cytochrome P450 (CYP) enzymes for which there is no functional information are considered "orphan" CYPs. Previous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ. Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. Toxicol Appl Pharmacol. 2016 Feb 4. pii: S0041-008X(16)30024-2. doi: 10.1016/j.taap.2016.02.001. [Epub ahead of print].

L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1 contributes to spinal cord regeneration in adult zebrafish

Authors:
Chen T, Yu Y, Hu C, Schachner M
Citation:
Restor Neurol Neurosci. 2016;[Epub ahead pf print] doi:10.3233/RNN-150602
Epub:
Yes
Abstract:
Purpose:The aim of the study was to investigate the functional role of L1.2, the zebrafish paralog of L1.1 and ortholog of...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen T, Yu Y, Hu C, Schachner M. L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1 contributes to spinal cord regeneration in adult zebrafish. Restor Neurol Neurosci. 2016;[Epub ahead pf print] doi:10.3233/RNN-150602.

Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes

Authors:
Luo Y, Lee I-W, Jo Y-J, Namgoong S, Kim N-H
Citation:
Sci Rep. 2016;6:20408. doi:10.1038/srep20408
Epub:
Not Epub
Abstract:
The SUN (Sad-1/UNC-84) and KASH (Klarsicht/ANC-1/Syne/homology) proteins constitute the linker of nucleoskeleton and...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Luo Y, Lee I-W, Jo Y-J, Namgoong S, Kim N-H. Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes. Sci Rep. 2016;6:20408. doi:10.1038/srep20408.

Zebrafish as a Model to Investigate Dynamin 2-Related Diseases

Authors:
Bragato B, Gaudenzi G, Blasevich F, Pavesi G, Maggi L, Giunta M, Cotelli F, Mora M
Citation:
Sci Rep. 2016;6:20466. doi:10.1038/srep20466
Epub:
Not Epub
Abstract:
Mutations in the dynamin-2 gene (DNM2) cause autosomal dominant centronuclear myopathy (CNM) and dominant intermediate Charcot-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bragato B, Gaudenzi G, Blasevich F, Pavesi G, Maggi L, Giunta M, Cotelli F, Mora M. Zebrafish as a Model to Investigate Dynamin 2-Related Diseases. Sci Rep. 2016;6:20466. doi:10.1038/srep20466.

Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation

Authors:
Zheng W, Shen F, Hu R, Roy B, Yang J, Wang Q, Zhang F, King JC, Sergi C, Liu SM, Cordat E, Tang J, Cao Y, Ali D, Chen XZ
Citation:
J Am Soc Nephrol. 2016 Feb 2. pii: ASN.2015070836. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Autosomal dominant polycystic kidney disease pathogenesis can be recapitulated in animal models by gene mutations in or dosage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng W, Shen F, Hu R, Roy B, Yang J, Wang Q, Zhang F, King JC, Sergi C, Liu SM, Cordat E, Tang J, Cao Y, Ali D, Chen XZ. Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. J Am Soc Nephrol. 2016 Feb 2. pii: ASN.2015070836. [Epub ahead of print].

Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin

Authors:
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C
Citation:
Nat Comm. 2016;7:10354. doi:10.1038/ncomms10354
Epub:
Not Epub
Abstract:
Development of the cerebral cortex requires regulation of proliferation and differentiation of neural stem cells and a diverse...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C. Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin. Nat Comm. 2016;7:10354. doi:10.1038/ncomms10354.

Detection of Klebsiella pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA

Authors:
Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M
Citation:
Mol Imaging Biol. 2016 Feb 1. [Epub ahead of print]
Epub:
Yes
Abstract:
PURPOSE: Previously, we demonstrated specific accumulation into bacteria of a 12-mer phosphorodiamidate morpholino (MORF)...
Organism or Cell Type:
mice
Citation Extract:
Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M. Detection of Klebsiella pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA. Mol Imaging Biol. 2016 Feb 1. [Epub ahead of print].

Two macrophage migration inhibitory factors regulate starfish larval immune cell chemotaxis

Authors:
Furukawa R, Tamaki K, Kaneko H
Citation:
Immunol Cell Biol. 2016 Apr;94(4):315-21. doi: 10.1038/icb.2016.6. Epub 2016 Feb 2.
Epub:
Yes
Abstract:
Immune cell recruitment is critical step in the inflammatory response and associated diseases. However, the underlying...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria pectinifera (sea star)
Citation Extract:
Furukawa R, Tamaki K, Kaneko H. Two macrophage migration inhibitory factors regulate starfish larval immune cell chemotaxis. Immunol Cell Biol. 2016 Apr;94(4):315-21. doi: 10.1038/icb.2016.6. Epub 2016 Feb 2..

Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration

Authors:
Govindan J, Tun KM, Iovine MK
Citation:
PLoS One. 2016 Feb 1;11(2):e0148202. doi: 10.1371/journal.pone.0148202. eCollection 2016
Epub:
Not Epub
Abstract:
Skeletal development is a tightly regulated process and requires proper communication between the cells for efficient exchange...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Govindan J, Tun KM, Iovine MK. Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration. PLoS One. 2016 Feb 1;11(2):e0148202. doi: 10.1371/journal.pone.0148202. eCollection 2016.

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