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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
CNS myelination requires cytoplasmic dynein function
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Citation:
Dev Dyn. 2015 Feb;244(2):134-45 Epub:
Not Epub Abstract:
BACKGROUND: Cytoplasmic dynein provides the main motor force for minus-end-directed transport of cargo on microtubules. Within... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang ML, Shin J, Kearns CA, Langworthy MM, Snell H, Walker MB, Appel B. CNS myelination requires cytoplasmic dynein function. Dev Dyn. 2015 Feb;244(2):134-45. |
Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish
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Citation:
Biol Open. 2015 Oct 30;4(11):1576-82. doi: 10.1242/bio.014225 Epub:
Not Epub Abstract:
The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mikami S, Nakaura M, Kawahara A, Mizoguchi T, Itoh M. Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish. Biol Open. 2015 Oct 30;4(11):1576-82. doi: 10.1242/bio.014225. |
Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis
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Citation:
J Biol Chem. 2015 Feb 6;290(6):3405-17. doi: 10.1074/jbc.M114.618611. Epub 2014 Nov 10 Epub:
Not Epub Abstract:
The formation of new vessels in the tumor, termed angiogenesis, is essential for primary tumor growth and facilitates tumor... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Delcourt N, Quevedo C, Nonne C, Fons P, O'Brien D, Loyaux D, Diez M, Autelitano F, Guillemot JC, Ferrara P, Muriana A, Callol C, Hérault JP, Herbert JM, Favre G, Bono F. Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis. J Biol Chem. 2015 Feb 6;290(6):3405-17. doi: 10.1074/jbc.M114.618611. Epub 2014 Nov 10. |
Extracellular Thiol Isomerases and Their Role in Thrombus Formation
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Citation:
Antioxid Redox Signal. 2016 Jan 1;24(1):1-15. doi: 10.1089/ars.2015.6530. Epub 2015 Nov 18 Epub:
Not Epub Abstract:
SIGNIFICANCE: The mammalian endoplasmic reticulum (ER) houses a large family of twenty thioredoxin-like proteins of which... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal. 2016 Jan 1;24(1):1-15. doi: 10.1089/ars.2015.6530. Epub 2015 Nov 18. |
Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission
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Citation:
J Neuromuscul Dis. 2014;1(1):75-90 Epub:
Not Epub Abstract:
BACKGROUND AND OBJECTIVE: Congenital myasthenic syndromes are rare inherited disorders characterized by fatigable weakness... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chaouch A, Porcelli V, Cox D, Edvardson S, Scarcia P, De Grassi A, Pierri CL, Cossins J, Laval SH, Griffin H, Müller JS, Evangelista T, Töpf A, Abicht A, Huebner A, von der Hagen M, Bushby K, Straub V, Horvath R, Elpeleg O, Palace J, Senderek J, Beeson D, Palmieri L, Lochmüller H. Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission. J Neuromuscul Dis. 2014;1(1):75-90. |
Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm
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Citation:
Sci Rep. 2016;6:21538 doi:10.1038/srep21538 Epub:
Not Epub Abstract:
MOG1 was initially identified as a protein that interacts with the small GTPase Ran involved in transport of macromolecules... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou J, Wang L, Zuo M, Wang X, Ahmed ASI, Chen Q, Wang QK. Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm. Sci Rep. 2016;6:21538 doi:10.1038/srep21538. |
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
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Citation:
Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112 Epub:
Yes Abstract:
Phosphorothioate (PS)-modified antisense oligonucleotides (ASOs) have been extensively investigated over the past three decades... Delivery Method:
cell bathing Organism or Cell Type:
cell culture: Stabilin cell lines Citation Extract: Miller CM, Donner AJ, Blank EE, Egger AW, Kellar BM, Østergaard ME, Seth PP, Harris EN. Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver. Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112. |
Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish
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Citation:
PLoS Genet. 2016;12(2):e1005881. doi:10.1371/journal.pgen.1005881 Epub:
Not Epub Abstract:
Unlike mammals and birds, teleost fish undergo external embryogenesis, and therefore their embryos are constantly challenged by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu M, Bai Y, Zhang C, Liu F, Cui Z, Chen J, Peng J. Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genet. 2016;12(2):e1005881. doi:10.1371/journal.pgen.1005881. |
Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques
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Citation:
PLoS Negl Trop Dis. 2016;10(2):e0004456. doi:10.1371/journal.pntd.0004456 Epub:
Not Epub Abstract:
Marburg virus (MARV) is an Ebola-like virus in the family Filovirdae that causes sporadic outbreaks of severe hemorrhagic fever... Delivery Method:
bolus iv injection Organism or Cell Type:
Macaca fascicularis (cynomolgus macaques) Citation Extract: Warren TK, Whitehouse CA, Wells J, Welch L, Charleston JS, Heald A, Nichols DK, Mattix ME, Palacios G, Kugleman JR, Iversen PI, Bavari S. Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques. PLoS Negl Trop Dis. 2016;10(2):e0004456. doi:10.1371/journal.pntd.0004456. |
Dynamin Binding Protein (Tuba) deficiency inhibits ciliogenesis and nephrogenesis in vitro and in vivo
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Citation:
J Biol Chem. 2016 Feb 19. pii: jbc.M115.688663. [Epub ahead of print] Epub:
Not Epub Abstract:
Dysfunction of renal primary cilia leads to polycystic kidney disease (PKD). We previously showed that the exocyst, a protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baek JI, Kwon SH, Zuo X, Kwon SY, Kim SH, Lipschutz JH. Dynamin Binding Protein (Tuba) deficiency inhibits ciliogenesis and nephrogenesis in vitro and in vivo. J Biol Chem. 2016 Feb 19. pii: jbc.M115.688663. [Epub ahead of print]. |