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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Molecular model for force production and transmission during vertebrate gastrulation

Authors:
Pfister K, Shook DR, Chang C, Keller R, Skoglund P.
Citation:
Development. 2016;143:715-727. doi:10.1242/dev.128090
Epub:
Not Epub
Abstract:
Vertebrate embryos undergo dramatic shape changes at gastrulation that require locally produced and anisotropically applied...
Link:
http://dev.biologists.org/content/143/4/715
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pfister K, Shook DR, Chang C, Keller R, Skoglund P.. Molecular model for force production and transmission during vertebrate gastrulation. Development. 2016;143:715-727. doi:10.1242/dev.128090.

Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype

Authors:
Nizzardo M, Simone C, Rizzo F, Ulzi G, Ramirez A, Rizzuti M, Bordoni A, Bucchia M, Gatti S, Bresolin N, Comi GP, Corti S
Citation:
Sci Rep. 2016;6:21301. doi:10.1038/srep21301
Epub:
Not Epub
Abstract:
Neurotoxicity due to the accumulation of mutant proteins is thought to drive pathogenesis in neurodegenerative diseases....
Link:
https://www.nature.com/articles/srep21301
Delivery Method:
electroporation, Vivo-Morpholino, ICV & ip injected bare Morpholino
Organism or Cell Type:
cell culture: HeLa, iPSC-derived motor neurons. mice.
Citation Extract:
Nizzardo M, Simone C, Rizzo F, Ulzi G, Ramirez A, Rizzuti M, Bordoni A, Bucchia M, Gatti S, Bresolin N, Comi GP, Corti S. Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype. Sci Rep. 2016;6:21301. doi:10.1038/srep21301.

Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development

Authors:
Marra AN, Wingert RA
Citation:
Dev Biol. 2016 Jan 29. pii: S0012-1606(15)30106-8. doi: 10.1016/j.ydbio.2016.01.035. [Epub ahead of print]
Epub:
Yes
Abstract:
Kidney development requires the differentiation and organization of discrete nephron epithelial lineages, yet the genetic and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615301068
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Wingert RA. Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development. Dev Biol. 2016 Jan 29. pii: S0012-1606(15)30106-8. doi: 10.1016/j.ydbio.2016.01.035. [Epub ahead of print].

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins

Authors:
Piacentino ML, Zuch DT, Fishman J, Rose S, Speranza EE, Li C, Yu J, Chung O, Ramachandran J, Ferrell P, Patel V, Reyna A, Hameeduddin H, Chaves J, Hewitt FB, Bardot E, Lee D, Core AB, Hogan JD, Keenan JL, Luo L, Coulombe-Huntington J, Blute TA, Oleinik E, Ibn-Salem J, Poustka AJ, Bradham CA
Citation:
Development. 2016 Jan 11. pii: dev.129312. [Epub ahead of print]
Epub:
Yes
Abstract:
The sea urchin larval skeleton offers a simple model for developmental pattern formation. The calcium carbonate skeleton is...
Link:
http://dev.biologists.org/content/143/4/703
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Piacentino ML, Zuch DT, Fishman J, Rose S, Speranza EE, Li C, Yu J, Chung O, Ramachandran J, Ferrell P, Patel V, Reyna A, Hameeduddin H, Chaves J, Hewitt FB, Bardot E, Lee D, Core AB, Hogan JD, Keenan JL, Luo L, Coulombe-Huntington J, Blute TA, Oleinik E, Ibn-Salem J, Poustka AJ, Bradham CA. RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins. Development. 2016 Jan 11. pii: dev.129312. [Epub ahead of print].

Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability

Authors:
Moreno RL, Ribera AB
Citation:
Neural Dev. 2014 Aug 22;9:19. doi: 10.1186/1749-8104-9-19
Epub:
Not Epub
Abstract:
BACKGROUND: In the spinal cord, stereotypic patterns of transcription factor expression uniquely identify neuronal subtypes....
Link:
http://neuraldevelopment.biomedcentral.com/articles/10.1186/1749-8104-9-19
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreno RL, Ribera AB. Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability. Neural Dev. 2014 Aug 22;9:19. doi: 10.1186/1749-8104-9-19.

In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus

Authors:
Barrett GL, Naim T, Trieu J, Huang M
Citation:
J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print]
Epub:
Yes
Abstract:
This study seeks to determine whether knockdown of basal forebrain p75 neurotrophin receptor (p75NTR ) expression elicits...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/jnr.23717/abstract
Delivery Method:
medial septa infusion
Organism or Cell Type:
Rat
Citation Extract:
Barrett GL, Naim T, Trieu J, Huang M. In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus. J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print].

Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation

Authors:
Yoshizaki G, Takashiba K, Shimamori S, Fujinuma K, Shikina S, Okutsu T, Kume S, Hayashi M
Citation:
Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print]
Epub:
Yes
Abstract:
We previously established a spermatogonial transplantation model in fish using triploid recipients. Although triploid salmonids...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mrd.22625/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Oncorhynchus mykiss (rainbow trout)
Citation Extract:
Yoshizaki G, Takashiba K, Shimamori S, Fujinuma K, Shikina S, Okutsu T, Kume S, Hayashi M. Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation. Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print].

DNA duplex-quadruplex exchange as the basis for a nanomolecular machine

Authors:
Alberti P, Mergny JL
Citation:
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 6
Epub:
Not Epub
Abstract:
There is currently great interest in the design of nanodevices that are capable of performing linear or rotary movements....
Link:
http://www.pnas.org/content/100/4/1569.long
Citation Extract:
Alberti P, Mergny JL. DNA duplex-quadruplex exchange as the basis for a nanomolecular machine. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 6.

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo

Authors:
Sempou E, Biasini E, Pinzón-Olejua A, Harris DA, Málaga-Trillo E
Citation:
Mol Neurodegener. 2016;11:18. doi:10.1186/s13024-016-0076-5
Epub:
Not Epub
Abstract:
Background: Prions and amyloid-β (Aβ) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal...
Link:
http://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-016-0076-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sempou E, Biasini E, Pinzón-Olejua A, Harris DA, Málaga-Trillo E. Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo. Mol Neurodegener. 2016;11:18. doi:10.1186/s13024-016-0076-5.

FOXE3 mutations predispose to thoracic aortic aneurysms and dissections

Authors:
Kuang SQ, Medina-Martinez O, Guo DC, Gong L, Regalado ES, Reynolds CL, Boileau C, Jondeau G, Prakash SK, Kwartler CS, Zhu LY, Peters AM, Duan XY, Bamshad MJ, Shendure J, Nickerson DA, Santos-Cortez RL, Dong X, Leal SM, Majesky MW, Swindell EC, Jamrich M, Milewicz DM
Citation:
J Clin Invest. 2016 Feb 8. pii: 83778. doi: 10.1172/JCI83778. [Epub ahead of print]
Epub:
Yes
Abstract:
The ascending thoracic aorta is designed to withstand biomechanical forces from pulsatile blood. Thoracic aortic aneurysms and...
Link:
http://jci.org/articles/view/83778
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuang SQ, Medina-Martinez O, Guo DC, Gong L, Regalado ES, Reynolds CL, Boileau C, Jondeau G, Prakash SK, Kwartler CS, Zhu LY, Peters AM, Duan XY, Bamshad MJ, Shendure J, Nickerson DA, Santos-Cortez RL, Dong X, Leal SM, Majesky MW, Swindell EC, Jamrich M, Milewicz DM. FOXE3 mutations predispose to thoracic aortic aneurysms and dissections. J Clin Invest. 2016 Feb 8. pii: 83778. doi: 10.1172/JCI83778. [Epub ahead of print].

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