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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Formin-2 regulates stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo

Authors:
Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A
Citation:
Development. 2016. 143:449-60. doi:10.1242/dev.130104
Epub:
Not Epub
Abstract:
Growth cone filopodia are actin-based mechanosensory structures that are essential for chemoreception and the generation of...
Delivery Method:
electroporation
Citation Extract:
Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A. Formin-2 regulates stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo. Development. 2016. 143:449-60. doi:10.1242/dev.130104.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling

Authors:
Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW
Citation:
Genes Dev. 2002 Apr 1;16(7):820-35
Epub:
Not Epub
Abstract:
We investigated the regulation of the activin/nodal-inducible distal element (DE) of the Xenopus goosecoid (gsc) promoter. On...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW. The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev. 2002 Apr 1;16(7):820-35.

Histone deacetylase 1 is required for the development of the zebrafish inner ear

Authors:
He Y, Tang D, Li W, Chai R, Li H
Citation:
Sci Rep. 2016;6:16535. doi:10.1038/srep16535
Epub:
Not Epub
Abstract:
Histone deacetylase 1 (HDAC1) has been reported to be important for multiple aspects of normal embryonic development, but...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He Y, Tang D, Li W, Chai R, Li H. Histone deacetylase 1 is required for the development of the zebrafish inner ear. Sci Rep. 2016;6:16535. doi:10.1038/srep16535.

MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis

Authors:
Wang X, Ling CC, Li L, Qin Y, Qi J, Liu X, You B, Shi Y, Zhang J, Jiang Q, Xu H, Sun C, You Y, Chai R, Liu D
Citation:
Cardiovasc Res. 2016 Jan 29. pii: cvw023. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNA-10 (miR-10) was originally shown to regulate angiogenesis by directly modulating the levels of membrane-bound fms-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Ling CC, Li L, Qin Y, Qi J, Liu X, You B, Shi Y, Zhang J, Jiang Q, Xu H, Sun C, You Y, Chai R, Liu D. MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovasc Res. 2016 Jan 29. pii: cvw023. [Epub ahead of print].

The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells

Authors:
Rodrigues-Diez RR, Garcia-Redondo AB, Orejudo M, Rodrigues-Diez R, Briones AM, Bosch-Panadero E, Kery G, Pato J, Ortiz A, Salaices M, Egido J, Ruiz-Ortega M
Citation:
Antioxid Redox Signal. 2015 Jan 1;22(1):29-47. doi: 10.1089/ars.2013.5500
Epub:
Not Epub
Abstract:
AIMS: Connective tissue growth factor (CTGF/CCN2) is a developmental gene upregulated in pathological conditions, including...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Rodrigues-Diez RR, Garcia-Redondo AB, Orejudo M, Rodrigues-Diez R, Briones AM, Bosch-Panadero E, Kery G, Pato J, Ortiz A, Salaices M, Egido J, Ruiz-Ortega M. The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells. Antioxid Redox Signal. 2015 Jan 1;22(1):29-47. doi: 10.1089/ars.2013.5500.

A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes

Authors:
Shahidi R, Williams EA, Conzelmann M, Asadulina A, Verasztó C, Jasek S, Bezares-Calderón LA, Jékely G
Citation:
Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Electron microscopy-based connectomics aims to comprehensively map synaptic connections in neural tissue. However, current...
Delivery Method:
microinjection
Organism or Cell Type:
Platynereis (annelid)
Citation Extract:
Shahidi R, Williams EA, Conzelmann M, Asadulina A, Verasztó C, Jasek S, Bezares-Calderón LA, Jékely G. A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes. Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print].

Gap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication

Authors:
Zong L, Zhu Y, Liang R, Zhao HB
Citation:
Sci Rep. 2016 Jan 27;6:19884. doi: 10.1038/srep19884
Epub:
Not Epub
Abstract:
Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and...
Delivery Method:
scrape loading
Organism or Cell Type:
cell culture HeLaCx43
Citation Extract:
Zong L, Zhu Y, Liang R, Zhao HB. Gap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication. Sci Rep. 2016 Jan 27;6:19884. doi: 10.1038/srep19884.

Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia

Authors:
Fernández-Murray JP, Prykhozhij SV, Dufay JN, Steele SL, Gaston D, Nasrallah GK, Coombs AJ, Liwski RS, Fernandez CV, Berman JN, McMaster CR
Citation:
PLoS Genet. 2016;12(1):e1005783. doi:10.1371/journal.pgen.1005783
Epub:
Not Epub
Abstract:
Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fernández-Murray JP, Prykhozhij SV, Dufay JN, Steele SL, Gaston D, Nasrallah GK, Coombs AJ, Liwski RS, Fernandez CV, Berman JN, McMaster CR. Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia. PLoS Genet. 2016;12(1):e1005783. doi:10.1371/journal.pgen.1005783.

Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability

Authors:
Kasher PR, Schertz KE, Thomas M, Jackson A, Annunziata S, Ballesta-Martinez MJ, Campeau PM, Clayton PE, Eaton J, Granata T, Guillén-Navarro E, Hernando C, Laverriere CE, Liedén A, Villa-Marcos O, McEntagart M, Nordgren A, Pantaleoni C, Pebrel-Richard C, Sarret C, Sciacca FL, Wright R, Kerr B, Glasgow E, Banka S
Citation:
Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2015.12.014
Epub:
Yes
Abstract:
Genetic studies of intellectual disability and identification of monogenic causes of obesity in humans have made immense...
Organism or Cell Type:
zebrafish
Citation Extract:
Kasher PR, Schertz KE, Thomas M, Jackson A, Annunziata S, Ballesta-Martinez MJ, Campeau PM, Clayton PE, Eaton J, Granata T, Guillén-Navarro E, Hernando C, Laverriere CE, Liedén A, Villa-Marcos O, McEntagart M, Nordgren A, Pantaleoni C, Pebrel-Richard C, Sarret C, Sciacca FL, Wright R, Kerr B, Glasgow E, Banka S. Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability. Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2015.12.014.

Epigenetic regulation of hematopoiesis by DNA methylation

Authors:
Gore AV, Athans B, Iben JR, Johnson K, Russanova V, Castranova D, Pham VN, Butler MG, Williams-Simons L, Nichols JT, Bresciani E, Feldman B, Kimmel CB, Liu PP, Weinstein BM
Citation:
Elife. 2016 Jan 27;5. pii: e11813. doi: 10.7554/eLife.11813.
Epub:
Not Epub
Abstract:
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gore AV, Athans B, Iben JR, Johnson K, Russanova V, Castranova D, Pham VN, Butler MG, Williams-Simons L, Nichols JT, Bresciani E, Feldman B, Kimmel CB, Liu PP, Weinstein BM. Epigenetic regulation of hematopoiesis by DNA methylation. Elife. 2016 Jan 27;5. pii: e11813. doi: 10.7554/eLife.11813..

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